ViewGene
Locus Name:
GeneID:
Location:

GeneID:2964
TrivialName: PA14_08390
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_08390
PAO1 Ortholog Locus:PA0654
Sequence Length:795
Protein Length:264
Start: 718670
Stop: 719464
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04043.1|AE004500_9 (AE004500) S-adenosylmethionine decarboxylase proenzyme [Pseudomonas aeruginosa PAO1]
Identities = 263/264 (99%), Positives = 263/264 (99%)
Sequence:
GTGAAAAGCAAACTCAAGCTCCACGGGTTCAACAACCTGACGAAGACCTTGAGCTTCAACATCTACGACATC
TGCTACGCCGAGACGCCCGAAGACCTCCAGGCCTACGTGCAGTACATCGACGAAGAGTATGACGCGGAGCGT
CTGACGCAGATTCTTACCGATGTTGTCGACATCATCGGCGCCAATATCCTGAACATCGCGCGTCAGGACTAC
GACCCCCAGGGCGCCAGCGTGACCATCCTGATCTCCGAGCAGCCGGTCACTCCGACCGACAGCCAGATCGAA
GAGTCCCCGGGCCCGCTGCCGGACACCATCCTGGCGCACCTGGACAAGAGCCACATCACCGTGCATACCTAC
CCGGAAATCCATCCGGTGGACGGCATCGCGACCTTCCGCGTGGACATCGATGTGTCCACCTGCGGAGTGATC
TCCCCGCTGAAGGCCCTGAACTACCTGATCCACCAGTTCGACTCGGACATCGTCACGGTCGACTATCGGGTC
CGCGGCTTCACCCGCGACATTGAGGGGCGCAAGCATTTCATCGACCACGAGATCAACTCGATCCAGAACTAT
CTCTCCGACGACACGCGCGAGGCCTACCAGATGACCGACGTGAACGTGTACCAGGAGAACCTGTTCCACACC
AAGATGCTGCTCAAGGACTTCGAACTGGAGAACTACCTGTTCGGCGACGCTACCCGGACGCTCTCGACGGAG
CAGCGCGAGCAGGTCACGGAACGGCTCAAGCACGAAATGCTGGAGATCTTCTACGCGCGCAACATGCCGCGC
TGA
Translation:
MKSKLKLHGFNNLTKTLSFNIYDICYAETPEDLQAYVQYIDEEYDAERLTQILTDVVDIIGANILNIARQDY
DPQGASVTILISEQPVTPTDSQIEESPGPLPDTILAHLDKSHITVHTYPEIHPVDGIATFRVDIDVSTCGVI
SPLKALNYLIHQFDSDIVTVDYRVRGFTRDIEGRKHFIDHEINSIQNYLSDDTREAYQMTDVNVYQENLFHT
KMLLKDFELENYLFGDATRTLSTEQREQVTERLKHEMLEIFYARNMPR*
AnnotationID:2972GeneID:2964
AnnotatorUID: diggins
Modification Date/Time: 2005-03-29 18:06:28
Gene Name:speD
Confidence Code:2
GeneProduct:S-adenosylmethionine decarboxylase proenzyme
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(8) Central intermediary metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam02675
Secondary Functional Category(ies):biosynthesis of cofactors, prosthetic groups and carriers
EC Number:4.1.1.50
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO54140.1| (AE016858) S-adenosylmethionine decarboxylase proenzyme
           [Pseudomonas syringae pv. tomato str. DC3000]
          Length = 264

 Score =  486 bits (1251), Expect = e-137
 Identities = 236/262 (90%), Positives = 251/262 (95%)

>gb|AAM84361.1|AE013680_3 (AE013680) S-adenosylmethionine decarboxylase [Yersinia pestis KIM]
          Length = 264

 Score =  389 bits (998), Expect = e-107
 Identities = 184/261 (70%), Positives = 215/261 (82%)

>gb|AAP15661.1| (AE016978) S-adenosylmethionine decarboxylase [Shigella flexneri 2a
           str. 2457T]
          Length = 264

 Score =  379 bits (973), Expect = e-104
 Identities = 180/260 (69%), Positives = 213/260 (81%)






 
Structural Features:
pfam02675, AdoMet_dc, S-adenosylmethionine decarboxylase.
CD-Length = 107 residues,  89.7% aligned
Score =  117 bits (295), Expect = 1e-27
Identities = 81/180 (45%), Positives = 90/180 (50%), Gaps = 46/180 (25%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14709




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:23073




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34613




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2964_cdd.html


    		




 
URL:

















    ReferenceID:35249




  
Author/Investigator(s):
        Tabor CW, Tabor H.





  
Title:
        The speEspeD operon of Escherichia coli. Formation and processing of a proenzyme form of S-adenosylmethionine decarboxylase.




  
PubMed:
        3316212


MedLine:
        




    
Source:
J Biol Chem. 1987 Nov 25;262(33):16037-40.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3316212









           
Homologs By Global Alignment 

           

       



     
Gene ID:2964
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
4803
                           PA0654_tr
                           translation of PA0654
                           264
                           99.62
                           99.62
                           0
                           1368.0
     

     
     
137274
                           gb|AAG04043.1|AE004500_9
                           (AE004500) S-adenosylmethionine decarboxylase proenzyme [Pseudomonas aeruginosa PAO1]
                           264
                           99.24
                           99.62
                           0
                           1365.0
     

     
     
137275
                           gb|AAO54140.1|
                           (AE016858) S-adenosylmethionine decarboxylase proenzyme [Pseudomonas syringae pv. tomato str. DC3000]
                           264
                           89.01
                           95.07
                           0
                           1243.0
     

     
     
137276
                           gb|AAM84361.1|AE013680_3
                           (AE013680) S-adenosylmethionine decarboxylase [Yersinia pestis KIM]
                           265
                           69.43
                           81.13
                           2
                           997.0
     

     
     
137277
                           emb|CAC92642.1|
                           (AJ414157) S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis CO92]
                           265
                           69.43
                           81.13
                           2
                           997.0
     

     






      

          
GC ORFID: 45966How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0654Glimmer Score: 

          
Start: 6520013Stop: 6520807

          
Length: 795


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA0654 translation of PA0654Homolog Bit Score 531.0

          
Other Homologs:  psyr_15may02_Scaffold14_revised_gene2362 (ORF: BLASTX 485.0), t_PA0654 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGAAAAGCAAACTCAAGCTCCACGGGTTCAACAACCTGACGAAGACCTTGAGCTTCAACATCTACGACATC 
TGCTACGCCGAGACGCCCGAAGACCTCCAGGCCTACGTGCAGTACATCGACGAAGAGTATGACGCGGAGCGT 
CTGACGCAGATTCTTACCGATGTTGTCGACATCATCGGCGCCAATATCCTGAACATCGCGCGTCAGGACTAC 
GACCCCCAGGGCGCCAGCGTGACCATCCTGATCTCCGAGCAGCCGGTCACTCCGACCGACAGCCAGATCGAA 
GAGTCCCCGGGCCCGCTGCCGGACACCATCCTGGCGCACCTGGACAAGAGCCACATCACCGTGCATACCTAC 
CCGGAAATCCATCCGGTGGACGGCATCGCGACCTTCCGCGTGGACATCGATGTGTCCACCTGCGGAGTGATC 
TCCCCGCTGAAGGCCCTGAACTACCTGATCCACCAGTTCGACTCGGACATCGTCACGGTCGACTATCGGGTC 
CGCGGCTTCACCCGCGACATTGAGGGGCGCAAGCATTTCATCGACCACGAGATCAACTCGATCCAGAACTAT 
CTCTCCGACGACACGCGCGAGGCCTACCAGATGACCGACGTGAACGTGTACCAGGAGAACCTGTTCCACACC 
AAGATGCTGCTCAAGGACTTCGAACTGGAGAACTACCTGTTCGGCGACGCTACCCGGACGCTCTCGACGGAG 
CAGCGCGAGCAGGTCACGGAACGGCTCAAGCACGAAATGCTGGAGATCTTCTACGCGCGCAACATGCCGCGC 
TGA