ViewGene
Locus Name:
GeneID:
Location:

GeneID:284
TrivialName: PA14_42080
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_42080
PAO1 Ortholog Locus:PA1737
Sequence Length:2145
Protein Length:714
Start: 3754605
Stop: 3752461
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05126.1|AE004600_2 (AE004600) probable 3-hydroxyacyl-CoA dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 713/714 (99%), Positives = 714/714 (100%)
Sequence:
ATGACTGACGCTATCCGTTACGAAAAAGGCCAGGACAACGTCGTCGTCCTGACCATGGACATGCCCGGGCAG
AGCGCCAACACCATGAACGGTGTCTACCGCGAGGCGATGGCGAAGACCATCGCGCGGCTGGAGGCGGAGAAA
GAGGGGATCGCCGGCGTGGTGCTGACCTCGGCGAAGAAGACCTTCTTCGCCGGCGGCGATCTCAACGAGCTG
ATCAAGGTCACCAAGGCCGACGCCCCGGCCTTCTACCAGGGCATCCTCGAACTCAAGGGCCAACTGCGGCGC
CTGGAGACCCTCGGCAAGCCGGTGGTCGCCGCGATCAACGGCGCTGCGCTGGGCGGCGGCTGGGAGATCTGC
CTGGCCTGCCACCACCGCATCGCCCTGGACAATCCCGGCGTGCAGCTCGGCCTGCCGGAGGTGACTCTCGGC
CTGTTGCCGGGCGGCGGCGGGGTGGTACGTATGGTGCGCCTGCTTGGTCTGGAGAAAGCCCTGCCGTACCTC
GCCGAAGGCAAGAAGGTGCGTCCGGCGGAAGCGCTCAAGGCCGGGCTGATCCACGAACTGGCCGACAGCCCC
GAGGAAATGCTGGAGAAGGCCCGCGCCTGGATCCTCGCCAACCCGGCGGCGAAGCAGCCCTGGGACAGCGCC
GGCTACAAGATTCCCGGCGGTACGCCTGCCAGTCCCAACGTGGCGCAGATGCTGGCCATCGCACCGTCGGTG
CTGCGCGACAAGACCAAGGGTTGCTTCCCGGCGCCCGAGAAGATCATGTGCGCGGCGGTGGAGGGCGCCCAG
GTCGATTTCGACACCGCGCAACTGATCGAGGCGCGCTATTTCACCGAGCTGACCACCGGCCAGGTGGCGAAG
AACATGATCGGCACCTTCTGGTTCCAGCTCAACGAGATCAACGCCGGCAAGTCGCGGCCGCAGGGGTATCCG
GTGCGGGCGACGAAAAAGGTCGGCGTGCTCGGCGCCGGGATGATGGGCGCGGGCATCGCCTACGTATCGGCG
GCGGCCGGCATCGAGGTGGTGCTCAAGGACGTCTCGCTGGAAGCGGCGGAGAAGGGCAAGGCCTATTCGGCC
AGGCTGCTGGACAAGAAAGTTGCGCGCGGGCACCTGTCCGCCGAGAAGCGCGACGCCTTCCTCGCGCGGATC
GTGCCGAGCGTCAGCGAAGCCGATTTCGAAGGCTGCGACCTGATCATCGAGGCGGTCTTCGAGGACCGCGCG
CTGAAAGGCAAGGTCACCGCCGAGGCCGAGAAGCATGCCCTGGCCGATGCGGTGGTGGCGTCCAATACCTCG
ACCCTGCCGATCACCGGGCTGGCCCAGGCGGTGGCGCGGCCGGAGAAGTTCATCGGCCTGCACTTCTTCAGC
CCGGTGGACAAGATGCCGCTGGTGGAGATCATCCGCGGCGAAAAGACCAGCGACGAAACCCTGGCACGCGGT
TTCGACTACGTGCTGCAGATCAAGAAAACGCCGATCGTGGTCAACGACAGCCGCGGCTTCTTCACCTCGCGG
GTATTCGGCACCTTCACCAACGAAGGCATCGCCATGCTCGGCGAAGGCGTGAGCGCCGCGATGATCGACAAC
CAGGCGCGCCAGGCCGGTATGCCGGTGGGGCCGCTGGCGATTTCCGACGAAGTCTCGCTGAGCCTGATGACC
CACATCCGCAACCAGACCGCCCGCGACCTCGAGGCCGAGGGCAAGGCtCTGCCGACGCACCCCGCGTTCGCC
GTGATCGACCTGATGGTCAATGAGTACAAGCGCCCGGGCAAGGCGGCCGGCGCCGGCTTCTACGACTACCCG
GCGAACGGCAGGAAACATCTCTGGGCGGAACTCAAGAGCCGCTTCGAGAAGCCCGATGCGCAAATATCCGCC
GAGGACGTACGCGACCGCCTGCTGTTCATCCAGGCCATCGAGACCGTTCGTTGCGTGGAGGAGGGGGTATTG
CACTCCACCGCCGACGCGAACATCGGCTCGATCTTCGGTATCGGTTTCGCCGCCTGGAGCGGGGGCGCCTTG
CAGTTCATCAACCAGTACGGCCTGAAGGACTTCATCGCCCGCGCCCAATACCTGGTCGAACAGTACGGCGAG
CGCTTCGAGCCGCCGGCGCTGTTGCTGGAGAAGGCGGCGAAGGGCGAGCTGTTCTGA
Translation:
MTDAIRYEKGQDNVVVLTMDMPGQSANTMNGVYREAMAKTIARLEAEKEGIAGVVLTSAKKTFFAGGDLNEL
IKVTKADAPAFYQGILELKGQLRRLETLGKPVVAAINGAALGGGWEICLACHHRIALDNPGVQLGLPEVTLG
LLPGGGGVVRMVRLLGLEKALPYLAEGKKVRPAEALKAGLIHELADSPEEMLEKARAWILANPAAKQPWDSA
GYKIPGGTPASPNVAQMLAIAPSVLRDKTKGCFPAPEKIMCAAVEGAQVDFDTAQLIEARYFTELTTGQVAK
NMIGTFWFQLNEINAGKSRPQGYPVRATKKVGVLGAGMMGAGIAYVSAAAGIEVVLKDVSLEAAEKGKAYSA
RLLDKKVARGHLSAEKRDAFLARIVPSVSEADFEGCDLIIEAVFEDRALKGKVTAEAEKHALADAVVASNTS
TLPITGLAQAVARPEKFIGLHFFSPVDKMPLVEIIRGEKTSDETLARGFDYVLQIKKTPIVVNDSRGFFTSR
VFGTFTNEGIAMLGEGVSAAMIDNQARQAGMPVGPLAISDEVSLSLMTHIRNQTARDLEAEGKALPTHPAFA
VIDLMVNEYKRPGKAAGAGFYDYPANGRKHLWAELKSRFEKPDAQISAEDVRDRLLFIQAIETVRCVEEGVL
HSTADANIGSIFGIGFAAWSGGALQFINQYGLKDFIARAQYLVEQYGERFEPPALLLEKAAKGELF*
AnnotationID:294GeneID:284
AnnotatorUID: diggins
Modification Date/Time: 2005-02-28 08:08:07
Gene Name:
Confidence Code:3
GeneProduct:putative 3-hydroxyacyl-CoA dehydrogenase
Cell Localization:()
Synonyms:fadB
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1250,pfam02737
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAB40682.1| (AL939129) putative fatty acid oxidative multifunctional enzyme
           [Streptomyces coelicolor A3(2)]
          Length = 726

 Score =  810 bits (2092), Expect = 0.0
 Identities = 423/715 (59%), Positives = 521/715 (72%), Gaps = 5/715 (0%)

>emb|CAA17666.1| (AL022004) fadB [Mycobacterium tuberculosis H37Rv]
          Length = 720

 Score =  763 bits (1971), Expect = 0.0
 Identities = 414/717 (57%), Positives = 497/717 (69%), Gaps = 15/717 (2%)

>emb|CAC31116.1| (AL583924) putative fatty oxidation complex alpha subunit
           [Mycobacterium leprae]
          Length = 714

 Score =  751 bits (1939), Expect = 0.0
 Identities = 403/711 (56%), Positives = 495/711 (69%), Gaps = 10/711 (1%)






 
Structural Features:
COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]
CD-Length = 307 residues,  94.1% aligned
Score =  302 bits (776), Expect = 6e-83
Identities = 139/294 (47%), Positives = 181/294 (61%), Gaps = 7/294 (2%)

pfam02737, 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
CD-Length = 185 residues, 100.0% aligned
Score =  203 bits (519), Expect = 4e-53
Identities = 85/185 (45%), Positives = 116/185 (62%)







   
Genomic Context:






   
Comment:


















    ReferenceID:571




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17713




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37156




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:284_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:284
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
469
                           PA1737_tr
                           translation of PA1737
                           714
                           99.85
                           99.99
                           0
                           3622.0
     

     
     
24431
                           gb|AAG05126.1|AE004600_2
                           (AE004600) probable 3-hydroxyacyl-CoA dehydrogenase [Pseudomonas aeruginosa PAO1]
                           714
                           99.85
                           99.99
                           0
                           3622.0
     

     
     
24432
                           emb|CAB40682.1|
                           (AL939129) putative fatty acid oxidative multifunctional enzyme [Streptomyces coelicolor A3(2)]
                           726
                           58.26
                           71.76
                           12
                           2096.0
     

     
     
24433
                           dbj|BAC69391.1|
                           (AP005027) putative fatty oxidation protein [Streptomyces avermitilis MA-4680]
                           735
                           58.09
                           70.34
                           21
                           2099.0
     

     
     
24435
                           emb|CAA17666.1|
                           (BX842574) PROBABLE FATTY OXIDATION PROTEIN FADB [Mycobacterium tuberculosis H37Rv]
                           729
                           57.06
                           68.31
                           24
                           1986.0
     

     






      

          
GC ORFID: 43286How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1737Glimmer Score: 

          
Start: 1199304Stop: 1201448

          
Length: 2145


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1737 translation of PA1737Homolog Bit Score 1399.0

          
Other Homologs:  t_PA1737 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACTGACGCTATCCGTTACGAAAAAGGCCAGGACAACGTCGTCGTCCTGACCATGGACATGCCCGGGCAG 
AGCGCCAACACCATGAACGGTGTCTACCGCGAGGCGATGGCGAAGACCATCGCGCGGCTGGAGGCGGAGAAA 
GAGGGGATCGCCGGCGTGGTGCTGACCTCGGCGAAGAAGACCTTCTTCGCCGGCGGCGATCTCAACGAGCTG 
ATCAAGGTCACCAAGGCCGACGCCCCGGCCTTCTACCAGGGCATCCTCGAACTCAAGGGCCAACTGCGGCGC 
CTGGAGACCCTCGGCAAGCCGGTGGTCGCCGCGATCAACGGCGCTGCGCTGGGCGGCGGCTGGGAGATCTGC 
CTGGCCTGCCACCACCGCATCGCCCTGGACAATCCCGGCGTGCAGCTCGGCCTGCCGGAGGTGACTCTCGGC 
CTGTTGCCGGGCGGCGGCGGGGTGGTACGTATGGTGCGCCTGCTTGGTCTGGAGAAAGCCCTGCCGTACCTC 
GCCGAAGGCAAGAAGGTGCGTCCGGCGGAAGCGCTCAAGGCCGGGCTGATCCACGAACTGGCCGACAGCCCC 
GAGGAAATGCTGGAGAAGGCCCGCGCCTGGATCCTCGCCAACCCGGCGGCGAAGCAGCCCTGGGACAGCGCC 
GGCTACAAGATTCCCGGCGGTACGCCTGCCAGTCCCAACGTGGCGCAGATGCTGGCCATCGCACCGTCGGTG 
CTGCGCGACAAGACCAAGGGTTGCTTCCCGGCGCCCGAGAAGATCATGTGCGCGGCGGTGGAGGGCGCCCAG 
GTCGATTTCGACACCGCGCAACTGATCGAGGCGCGCTATTTCACCGAGCTGACCACCGGCCAGGTGGCGAAG 
AACATGATCGGCACCTTCTGGTTCCAGCTCAACGAGATCAACGCCGGCAAGTCGCGGCCGCAGGGGTATCCG 
GTGCGGGCGACGAAAAAGGTCGGCGTGCTCGGCGCCGGGATGATGGGCGCGGGCATCGCCTACGTATCGGCG 
GCGGCCGGCATCGAGGTGGTGCTCAAGGACGTCTCGCTGGAAGCGGCGGAGAAGGGCAAGGCCTATTCGGCC 
AGGCTGCTGGACAAGAAAGTTGCGCGCGGGCACCTGTCCGCCGAGAAGCGCGACGCCTTCCTCGCGCGGATC 
GTGCCGAGCGTCAGCGAAGCCGATTTCGAAGGCTGCGACCTGATCATCGAGGCGGTCTTCGAGGACCGCGCG 
CTGAAAGGCAAGGTCACCGCCGAGGCCGAGAAGCATGCCCTGGCCGATGCGGTGGTGGCGTCCAATACCTCG 
ACCCTGCCGATCACCGGGCTGGCCCAGGCGGTGGCGCGGCCGGAGAAGTTCATCGGCCTGCACTTCTTCAGC 
CCGGTGGACAAGATGCCGCTGGTGGAGATCATCCGCGGCGAAAAGACCAGCGACGAAACCCTGGCACGCGGT 
TTCGACTACGTGCTGCAGATCAAGAAAACGCCGATCGTGGTCAACGACAGCCGCGGCTTCTTCACCTCGCGG 
GTATTCGGCACCTTCACCAACGAAGGCATCGCCATGCTCGGCGAAGGCGTGAGCGCCGCGATGATCGACAAC 
CAGGCGCGCCAGGCCGGTATGCCGGTGGGGCCGCTGGCGATTTCCGACGAAGTCTCGCTGAGCCTGATGACC 
CACATCCGCAACCAGACCGCCCGCGACCTCGAGGCCGAGGGCAAGGCtCTGCCGACGCACCCCGCGTTCGCC 
GTGATCGACCTGATGGTCAATGAGTACAAGCGCCCGGGCAAGGCGGCCGGCGCCGGCTTCTACGACTACCCG 
GCGAACGGCAGGAAACATCTCTGGGCGGAACTCAAGAGCCGCTTCGAGAAGCCCGATGCGCAAATATCCGCC 
GAGGACGTACGCGACCGCCTGCTGTTCATCCAGGCCATCGAGACCGTTCGTTGCGTGGAGGAGGGGGTATTG 
CACTCCACCGCCGACGCGAACATCGGCTCGATCTTCGGTATCGGTTTCGCCGCCTGGAGCGGGGGCGCCTTG 
CAGTTCATCAACCAGTACGGCCTGAAGGACTTCATCGCCCGCGCCCAATACCTGGTCGAACAGTACGGCGAG 
CGCTTCGAGCCGCCGGCGCTGTTGCTGGAGAAGGCGGCGAAGGGCGAGCTGTTCTGA