ViewGene
Locus Name:
GeneID:
Location:

GeneID:2638
TrivialName: PA14_70280
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_70280
PAO1 Ortholog Locus:PA5323
Sequence Length:906
Protein Length:301
Start: 6266710
Stop: 6267615
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08708.1|AE004945_2 (AE004945) acetylglutamate kinase [Pseudomonas aeruginosa PAO1]
Identities = 301/301 (100%), Positives = 301/301 (100%)
Sequence:
ATGACCCTGAGTCGCGATGACGCCGCCCAGGTTGCCAAGGTCCTTTCCGAGGCCCTGCCCTACATCCGCCGC
TTCGTCGGCAAGACGCTGGTGATCAAGTACGGCGGCAACGCCATGGAGAGCGAGGAGCTGAAGGCCGGCTTC
GCCCGCGACGTGGTGCTGATGAAAGCGGTCGGCATCAACCCGGTGGTGGTGCATGGCGGCGGCCCGCAGATC
GGCGACCTGCTCAAGCGCCTGTCGATCGAGAGCCACTTCATCGACGGCATGCGCGTCACCGATGCGGCGACC
ATGGACGTGGTGGAGATGGTCCTCGGCGGCCAGGTGAACAAGGACATCGTCAACCTGATCAACCGCCACGGC
GGCAGCGCCATCGGCCTGACCGGCAAGGACGCCGAGCTGATCCGTGCGAAGAAGCTCACCGTGACCCGCCAG
ACCCCGGAGATGACCAAGCCGGAGATCATCGACATCGGCCATGTGGGCGAAGTCACCGGGGTCAACGTCGGG
CTGCTGAACATGCTGGTCAAGGGCGACTTCATTCCGGTGATCGCGCCGATCGGCGTGGGCAGCAACGGCGAG
TCCTACAACATCAACGCCGACCTGGTGGCCGGCAAGGTGGCGGAAGCGCTGAAGGCCGAGAAATTGATGCTG
CTGACCAACATCGCCGGCCTGATGGACAAGCAGGGCCAGGTGCTGACCGGGCTGTCCACCGAACAGGTCAAC
GAGCTGATCGCCGACGGCACCATCTACGGCGGCATGCTGCCGAAGATCCGCTGCGCCCTGGAAGCGGTGCAG
GGCGGCGTGACCAGCGCGCACATCATCGATGGCCGGGTGCCGAATGCCGTGCTGCTGGAAATCTTCACCGAC
AGCGGCGTCGGCACCCTGATCAGCAACCGCAAGCGTCACTGA
Translation:
MTLSRDDAAQVAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKAGFARDVVLMKAVGINPVVVHGGGPQI
GDLLKRLSIESHFIDGMRVTDAATMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRAKKLTVTRQ
TPEMTKPEIIDIGHVGEVTGVNVGLLNMLVKGDFIPVIAPIGVGSNGESYNINADLVAGKVAEALKAEKLML
LTNIAGLMDKQGQVLTGLSTEQVNELIADGTIYGGMLPKIRCALEAVQGGVTSAHIIDGRVPNAVLLEIFTD
SGVGTLISNRKRH*
AnnotationID:2646GeneID:2638
AnnotatorUID: diggins
Modification Date/Time: 2005-04-26 19:07:28
Gene Name:argB
Confidence Code:2
GeneProduct:acetylglutamate kinase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0548,pfam00696
Secondary Functional Category(ies):
EC Number:2.7.2.8
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO53636.1| (AE016856) acetylglutamate kinase [Pseudomonas syringae pv. tomato
           str. DC3000]
          Length = 301

 Score =  542 bits (1397), Expect = e-154
 Identities = 279/301 (92%), Positives = 289/301 (96%)

>gb|AAN70854.1|AE016729_12 (AE016793) acetylglutamate kinase [Pseudomonas putida KT2440]
          Length = 301

 Score =  541 bits (1395), Expect = e-153
 Identities = 277/299 (92%), Positives = 289/299 (96%)

>emb|CAD84916.1| (BX321859) Aspartokinase superfamily:Acetylglutamate kinase
           [Nitrosomonas europaea ATCC 19718]
          Length = 295

 Score =  363 bits (932), Expect = e-100
 Identities = 188/282 (66%), Positives = 226/282 (80%), Gaps = 3/282 (1%)








 
Structural Features:
COG0548, ArgB, Acetylglutamate kinase [Amino acid transport and metabolism]
CD-Length = 265 residues,  99.6% aligned
Score =  314 bits (806), Expect = 8e-87
Identities = 144/273 (52%), Positives = 193/273 (70%), Gaps = 11/273 (4%)

pfam00696, AA_kinase, Amino acid kinase family.
CD-Length = 236 residues, 100.0% aligned
Score =  124 bits (313), Expect = 1e-29
Identities = 72/257 (28%), Positives = 118/257 (45%), Gaps = 31/257 (12%)






   
Genomic Context:






   
Comment:


















    ReferenceID:5279




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:22424




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34757




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2638_cdd.html


    		




 
URL:

















    ReferenceID:35699




  
Author/Investigator(s):
        Ruepp A, Muller HN, Lottspeich F, Soppa J.





  
Title:
        Catabolic ornithine transcarbamylase of Halobacterium halobium (salinarium): purification, characterization, sequence determination, and evolution.




  
PubMed:
        7868583


MedLine:
        




    
Source:
J Bacteriol. 1995 Mar;177(5):1129-36.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7868583

















    ReferenceID:35700




  
Author/Investigator(s):
        Parsot C, Boyen A, Cohen GN, Glansdorff N.





  
Title:
        Nucleotide sequence of Escherichia coli argB and argC genes: comparison of N-acetylglutamate kinase and N-acetylglutamate-gamma-semialdehyde dehydrogenase with homologous and analogous enzymes.




  
PubMed:
        2851495


MedLine:
        




    
Source:
Gene. 1988 Sep 7;68(2):275-83.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2851495









           
Homologs By Global Alignment 

           

       



     
Gene ID:2638
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
4354
                           PA5323_tr
                           translation of PA5323
                           301
                           99.99
                           99.99
                           0
                           1498.0
     

     
     
127330
                           gb|AAG08708.1|AE004945_2
                           (AE004945) acetylglutamate kinase [Pseudomonas aeruginosa PAO1]
                           301
                           99.99
                           99.99
                           0
                           1498.0
     

     
     
127331
                           gb|AAO53636.1|
                           (AE016856) acetylglutamate kinase [Pseudomonas syringae pv. tomato str. DC3000]
                           301
                           92.69
                           96.01
                           0
                           1397.0
     

     
     
127332
                           gb|AAN70854.1|AE016729_12
                           (AE016793) acetylglutamate kinase [Pseudomonas putida KT2440]
                           301
                           92.02
                           96.01
                           0
                           1393.0
     

     
     
127334
                           emb|CAD84916.1|
                           (BX321859) Aspartokinase superfamily:Acetylglutamate kinase [Nitrosomonas europaea ATCC 19718]
                           301
                           62.79
                           75.74
                           6
                           927.0
     

     






      

          
GC ORFID: 45640How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA5323Glimmer Score: 

          
Start: 5530399Stop: 5531304

          
Length: 906


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA5323 translation of PA5323Homolog Bit Score 581.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene3935 (ORF: BLASTX 542.0), t_PA5323 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCCTGAGTCGCGATGACGCCGCCCAGGTTGCCAAGGTCCTTTCCGAGGCCCTGCCCTACATCCGCCGC 
TTCGTCGGCAAGACGCTGGTGATCAAGTACGGCGGCAACGCCATGGAGAGCGAGGAGCTGAAGGCCGGCTTC 
GCCCGCGACGTGGTGCTGATGAAAGCGGTCGGCATCAACCCGGTGGTGGTGCATGGCGGCGGCCCGCAGATC 
GGCGACCTGCTCAAGCGCCTGTCGATCGAGAGCCACTTCATCGACGGCATGCGCGTCACCGATGCGGCGACC 
ATGGACGTGGTGGAGATGGTCCTCGGCGGCCAGGTGAACAAGGACATCGTCAACCTGATCAACCGCCACGGC 
GGCAGCGCCATCGGCCTGACCGGCAAGGACGCCGAGCTGATCCGTGCGAAGAAGCTCACCGTGACCCGCCAG 
ACCCCGGAGATGACCAAGCCGGAGATCATCGACATCGGCCATGTGGGCGAAGTCACCGGGGTCAACGTCGGG 
CTGCTGAACATGCTGGTCAAGGGCGACTTCATTCCGGTGATCGCGCCGATCGGCGTGGGCAGCAACGGCGAG 
TCCTACAACATCAACGCCGACCTGGTGGCCGGCAAGGTGGCGGAAGCGCTGAAGGCCGAGAAATTGATGCTG 
CTGACCAACATCGCCGGCCTGATGGACAAGCAGGGCCAGGTGCTGACCGGGCTGTCCACCGAACAGGTCAAC 
GAGCTGATCGCCGACGGCACCATCTACGGCGGCATGCTGCCGAAGATCCGCTGCGCCCTGGAAGCGGTGCAG 
GGCGGCGTGACCAGCGCGCACATCATCGATGGCCGGGTGCCGAATGCCGTGCTGCTGGAAATCTTCACCGAC 
AGCGGCGTCGGCACCCTGATCAGCAACCGCAAGCGTCACTGA