ViewGene
Locus Name:
GeneID:
Location:

GeneID:2417
TrivialName: PA14_63620
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_63620
PAO1 Ortholog Locus:PA4813
Sequence Length:930
Protein Length:309
Start: 5673585
Stop: 5672656
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAC34733.1| (U75975) lipase [Pseudomonas aeruginosa]
Identities = 309/309 (100%), Positives = 309/309 (100%)
Sequence:
ATGAACAAGAACAAGACGTTCCTCGCGGCGGCGCTGGTAGCGCTGGCCGCCAGCCTTCCCGTGCACGCTGCG
ACCGACTACACCCGCACGCGCTATCCCATCGTGCTGTCCCACGGTCTGTTCGGCTTCAAGAGCGTCGGCCCG
GTGGACTACTGGCACGCTATCGTGCCGGCCCTGGAGAAGGACGGCGCGAAGGTCTTCGCCACCTCGCAGTCG
CCGGTGAACAGCAACGAGGTGCGCGGCGAACAGCTACTGGCGCAGGTGGAGGAAGTCCTGGCCCTGACCGGC
GCGGAGAAAGTCAACCTGATCGGCCACAGCCAGGGCGGCATGACCGTGCGCTACGTCGCCGGGGTGGCGCCG
CAACTGGTGGCCTCGGTCACCACCATGGGCACGCCGCACAAGGGCACGCCGGTAGCCGACGCGGTGACCGGC
TTCAGCGAGTTCCTCGGGCCGATCGGCACCGAGGTGATCGCCTCGGCGGTGGAGGCGCTGTTCTCGGTGGTC
GACATCGTCGACGGCGGCGAGTGGGTCAAGGGCGACGCGCTGGCTGCCCTGAACAGTCTCAACACTCCCGGC
ACCGCGCGGTTCAACCAGCGCTTCCCGCAGGCGATCCCGGCCAGCGCCTGTGGCCAGGGCGCGGAGACGGTA
GCCGGGGTGCGCTACTACTCGATGAGCGGCACCGGCTCCCTGACCAATGCGCTCGACCCGAGCTCCGCCGGC
CTGGCGGTGACCGGGCTGCTGTTCGGCGAGGCCAACGACGGTCTGGTCGGCCAATGCTCCAGCCACCTGGGC
AGCGTGGTGAAGGACAACTACCGGATGGACCATCTGGACGAAGTCAACCAGTTGCTCGGCCTGGTCAGCCTG
TTCGAGAGCGACCCGACCCAGGTCTATCGGCAGCATGCCAATCGCCTCAGGAACGTCGGACTCTGA
Translation:
MNKNKTFLAAALVALAASLPVHAATDYTRTRYPIVLSHGLFGFKSVGPVDYWHAIVPALEKDGAKVFATSQS
PVNSNEVRGEQLLAQVEEVLALTGAEKVNLIGHSQGGMTVRYVAGVAPQLVASVTTMGTPHKGTPVADAVTG
FSEFLGPIGTEVIASAVEALFSVVDIVDGGEWVKGDALAALNSLNTPGTARFNQRFPQAIPASACGQGAETV
AGVRYYSMSGTGSLTNALDPSSAGLAVTGLLFGEANDGLVGQCSSHLGSVVKDNYRMDHLDEVNQLLGLVSL
FESDPTQVYRQHANRLRNVGL*
AnnotationID:2425GeneID:2417
AnnotatorUID: diggins
Modification Date/Time: 2005-04-25 20:08:07
Gene Name:lipC
Confidence Code:1
GeneProduct:lipase LipC
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1075
Secondary Functional Category(ies):
EC Number:3.1.1.3
Status:ACTIVE
Pathway:






 
Homology:






 
Structural Features:
COG1075, LipA, Predicted acetyltransferases and hydrolases 
with the alpha/beta hydrolase fold 
CD-Length = 336 residues,  92.0% aligned
Score =  230 bits (588), Expect = 1e-61
Identities = 128/317 (40%), Positives = 161/317 (50%), Gaps = 19/317 (5%)






   
Genomic Context:






   
Comment:


















    ReferenceID:4837




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21983




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:35236




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2417_cdd.html


    		




 
URL:

















    ReferenceID:35987




  
Author/Investigator(s):
        Martinez A, Ostrovsky P, Nunn DN.





  
Title:
        LipC, a second lipase of Pseudomonas aeruginosa, is LipB and Xcp dependent and is transcriptionally regulated by pilus biogenesis components.




  
PubMed:
        10564475


MedLine:
        




    
Source:
Mol Microbiol. 1999 Oct;34(2):317-26.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10564475

















    ReferenceID:35988




  
Author/Investigator(s):
        Akatsuka H, Kawai E, Omori K, Shibatani T.





  
Title:
        The three genes lipB, lipC, and lipD involved in the extracellular secretion of the Serratia marcescens lipase which lacks an N-terminal signal peptide.




  
PubMed:
        7592412


MedLine:
        




    
Source:
J Bacteriol. 1995 Nov;177(22):6381-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7592412









           
Homologs By Global Alignment 

           

       



     
Gene ID:2417
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
122009
                           gb|AAC34733.1|
                           (U75975) lipase [Pseudomonas aeruginosa]
                           309
                           99.99
                           99.99
                           0
                           1569.0
     

     
     
4068
                           PA4813_tr
                           translation of PA4813
                           309
                           99.67
                           99.67
                           0
                           1565.0
     

     
     
122010
                           gb|AAG08198.1|AE004894_4
                           (AE004894) lipase LipC [Pseudomonas aeruginosa PAO1]
                           309
                           99.67
                           99.67
                           0
                           1565.0
     

     
     
122011
                           gb|AAM14701.1|
                           (AY091666) LipA [Pseudomonas mendocina]
                           313
                           56.86
                           71.24
                           6
                           884.0
     

     
     
4069
                           PA2862_tr
                           translation of PA2862
                           319
                           53.60
                           68.02
                           18
                           839.0
     

     






      

          
GC ORFID: 45419How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4813Glimmer Score: 

          
Start: 4937265Stop: 4936336

          
Length: 930


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4813 translation of PA4813Homolog Bit Score 607.0

          
Other Homologs:  t_PA2862 (ORF: BLASTX 325.0), t_PA4813 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACAAGAACAAGACGTTCCTCGCGGCGGCGCTGGTAGCGCTGGCCGCCAGCCTTCCCGTGCACGCTGCG 
ACCGACTACACCCGCACGCGCTATCCCATCGTGCTGTCCCACGGTCTGTTCGGCTTCAAGAGCGTCGGCCCG 
GTGGACTACTGGCACGCTATCGTGCCGGCCCTGGAGAAGGACGGCGCGAAGGTCTTCGCCACCTCGCAGTCG 
CCGGTGAACAGCAACGAGGTGCGCGGCGAACAGCTACTGGCGCAGGTGGAGGAAGTCCTGGCCCTGACCGGC 
GCGGAGAAAGTCAACCTGATCGGCCACAGCCAGGGCGGCATGACCGTGCGCTACGTCGCCGGGGTGGCGCCG 
CAACTGGTGGCCTCGGTCACCACCATGGGCACGCCGCACAAGGGCACGCCGGTAGCCGACGCGGTGACCGGC 
TTCAGCGAGTTCCTCGGGCCGATCGGCACCGAGGTGATCGCCTCGGCGGTGGAGGCGCTGTTCTCGGTGGTC 
GACATCGTCGACGGCGGCGAGTGGGTCAAGGGCGACGCGCTGGCTGCCCTGAACAGTCTCAACACTCCCGGC 
ACCGCGCGGTTCAACCAGCGCTTCCCGCAGGCGATCCCGGCCAGCGCCTGTGGCCAGGGCGCGGAGACGGTA 
GCCGGGGTGCGCTACTACTCGATGAGCGGCACCGGCTCCCTGACCAATGCGCTCGACCCGAGCTCCGCCGGC 
CTGGCGGTGACCGGGCTGCTGTTCGGCGAGGCCAACGACGGTCTGGTCGGCCAATGCTCCAGCCACCTGGGC 
AGCGTGGTGAAGGACAACTACCGGATGGACCATCTGGACGAAGTCAACCAGTTGCTCGGCCTGGTCAGCCTG 
TTCGAGAGCGACCCGACCCAGGTCTATCGGCAGCATGCCAATCGCCTCAGGAACGTCGGACTCTGA