ViewGene
Locus Name:
GeneID:
Location:

GeneID:2260
TrivialName: PA14_35320
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_35320
PAO1 Ortholog Locus:PA2263
Sequence Length:987
Protein Length:328
Start: 3140911
Stop: 3139925
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05651.1|AE004652_4 (AE004652) probable 2-hydroxyacid dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 323/328 (98%), Positives = 326/328 (99%)
Sequence:
ATGAAGAAAGTGGTTCTCTACAAACGTCTCTCCGCGCCCCTGATGGAACGCCTGCGCGAACGGGTCGAGGTG
CTCCTGATCGAGGAGCCCGGCCGCGACGGCCTGGCCCGCTTGCGCGACGCCCTGCCCGAGGCCCACGGCCTG
CTCGGCGCCAGCCTGCGCCTGGAGGCCGGACTGCTCGACCTGGCACCGCGACTGGAAGCCATCGCCAGCGTC
TCGGTGGGCGTCGACAACTATGACATCGACTACCTCGACCGCCGCGGCATCCTCCTCAGCAATACCCCCGAC
GTGCTCACCGAGACCACCGCCGACACCGGCTTCGCGCTGATCCTGGCGACAGCCCGGCGGGTAGTGGAACTG
GCCGGCTGGGTGCGCGCCGGGGAATGGAAGAAGAGCGTCGGCGCCGCCCAGTTCGGTACCGACGTGCATGGC
AAGACCCTCGGTATCGTCGGCATGGGCCGCATCGGCGAGGCCCTGGCCCGGCGCGGGCACCACGGCTTCGGC
ATGCGCGTGCTGTACCACAGCCATAGCCCGAAGCCCCACGTCGAAGAACGCTACGCAGCGAGCTACCGCTCC
CTCGACGCGCTGCTCGAGGAATCCGACTTCGTCTGCCTGACCCTGCCGCTGACCGCCGCCACCGAAGGCCTG
ATCGGTGCCGCGCAGTTCGCCCGGATGCGTCCACAGGCGATCTTCATCAACATCTCCCGTGGCCGGGTGATC
GACGAGGCGGCCCTGATCGAGGCCCTGGCCCAGCGGCGGATCCGCGCCGCCGGCCTCGACGTGTTCGAGCGC
GAGCCGCTGTCTCCCGACTCGCCGCTGCTGCGCCTGCCGAACGTGGTGGCCACCCCGCACATCGGCTCGGCC
ACCGAGGAAACCCGCGAAGCCATGGCCCGCTGCGCGGTGGACAACCTGCTGGCCGCCCTCGCCGGCGAGCGG
CCGCTGAACCTGGTCAATCCTTCGGCCTGGGCGCGACGGCGAGGCGCCTGA
Translation:
MKKVVLYKRLSAPLMERLRERVEVLLIEEPGRDGLARLRDALPEAHGLLGASLRLEAGLLDLAPRLEAIASV
SVGVDNYDIDYLDRRGILLSNTPDVLTETTADTGFALILATARRVVELAGWVRAGEWKKSVGAAQFGTDVHG
KTLGIVGMGRIGEALARRGHHGFGMRVLYHSHSPKPHVEERYAASYRSLDALLEESDFVCLTLPLTAATEGL
IGAAQFARMRPQAIFINISRGRVIDEAALIEALAQRRIRAAGLDVFEREPLSPDSPLLRLPNVVATPHIGSA
TEETREAMARCAVDNLLAALAGERPLNLVNPSAWARRRGA*
AnnotationID:2268GeneID:2260
AnnotatorUID: diggins
Modification Date/Time: 2005-04-29 06:06:27
Gene Name:
Confidence Code:3
GeneProduct:2-ketogluconate 6-phosphate reductase
Cell Localization:()
Synonyms:kguD
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(12) Energy metabolism
Alternate Gene Product Name:putative putative 2-hydroxyacid dehydrogenase
Functional Category Confidence Code:5
COGs:COG1052,COG0111
Secondary Functional Category(ies):coenzyme metabolism
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN68980.1|AE016530_3 (AE016786) 2-ketogluconate 6-phosphate reductase [Pseudomonas
           putida KT2440]
          Length = 320

 Score =  462 bits (1190), Expect = e-130
 Identities = 238/317 (75%), Positives = 269/317 (84%)

>gb|AAN82808.1|AE016768_226 (AE016768) 2-ketogluconate reductase [Escherichia coli CFT073]
          Length = 328

 Score =  332 bits (850), Expect = 2e-90
 Identities = 179/316 (56%), Positives = 219/316 (69%)

>gb|AAP19150.1| (AE016992) putative dehydrogenase [Shigella flexneri 2a str. 2457T]
          Length = 324

 Score =  328 bits (841), Expect = 3e-89
 Identities = 178/316 (56%), Positives = 217/316 (68%)








 
Structural Features:
COG1052, LdhA, Lactate dehydrogenase and related dehydrogenases 
[Energy production and conversion / Coenzyme metabolism]
CD-Length = 324 residues,  99.7% aligned
Score =  321 bits (824), Expect = 7e-89
Identities = 153/325 (47%), Positives = 198/325 (60%), Gaps = 8/325 (2%)

COG0111, SerA, Phosphoglycerate dehydrogenase and related dehydrogenases 
[Amino acid transport and metabolism]
CD-Length = 324 residues,  96.9% aligned
Score =  267 bits (684), Expect = 1e-72
Identities = 130/319 (40%), Positives = 184/319 (57%), Gaps = 6/319 (1%)






   
Genomic Context:






   
Comment:
other possible gene name: yiaE


















    ReferenceID:4523




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21669




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32516




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2260_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:2260
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3845
                           PA2263_tr
                           translation of PA2263
                           328
                           98.47
                           99.39
                           0
                           1630.0
     

     
     
117889
                           gb|AAG05651.1|AE004652_4
                           (AE004652) probable 2-hydroxyacid dehydrogenase [Pseudomonas aeruginosa PAO1]
                           328
                           98.47
                           99.39
                           0
                           1630.0
     

     
     
117890
                           gb|AAK37650.1|
                           (AF012100) KguD [Pseudomonas aeruginosa]
                           328
                           98.47
                           99.39
                           0
                           1630.0
     

     
     
117891
                           gb|AAN68980.1|AE016530_3
                           (AE016786) 2-ketogluconate 6-phosphate reductase [Pseudomonas putida KT2440]
                           329
                           72.34
                           81.76
                           10
                           1187.0
     

     
     
3846
                           PA3896_tr
                           translation of PA3896
                           329
                           56.83
                           72.64
                           5
                           928.0
     

     






      

          
GC ORFID: 45262How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2263Glimmer Score: 

          
Start: 1813005Stop: 1813991

          
Length: 987


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2263 translation of PA2263Homolog Bit Score 632.0

          
Other Homologs:  t_PA3896 (ORF: BLASTX 360.0), psyr_15may02_Scaffold3_revised_gene5011 (ORF: BLASTX 343.0), t_PA2263 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAAGAAAGTGGTTCTCTACAAACGTCTCTCCGCGCCCCTGATGGAACGCCTGCGCGAACGGGTCGAGGTG 
CTCCTGATCGAGGAGCCCGGCCGCGACGGCCTGGCCCGCTTGCGCGACGCCCTGCCCGAGGCCCACGGCCTG 
CTCGGCGCCAGCCTGCGCCTGGAGGCCGGACTGCTCGACCTGGCACCGCGACTGGAAGCCATCGCCAGCGTC 
TCGGTGGGCGTCGACAACTATGACATCGACTACCTCGACCGCCGCGGCATCCTCCTCAGCAATACCCCCGAC 
GTGCTCACCGAGACCACCGCCGACACCGGCTTCGCGCTGATCCTGGCGACAGCCCGGCGGGTAGTGGAACTG 
GCCGGCTGGGTGCGCGCCGGGGAATGGAAGAAGAGCGTCGGCGCCGCCCAGTTCGGTACCGACGTGCATGGC 
AAGACCCTCGGTATCGTCGGCATGGGCCGCATCGGCGAGGCCCTGGCCCGGCGCGGGCACCACGGCTTCGGC 
ATGCGCGTGCTGTACCACAGCCATAGCCCGAAGCCCCACGTCGAAGAACGCTACGCAGCGAGCTACCGCTCC 
CTCGACGCGCTGCTCGAGGAATCCGACTTCGTCTGCCTGACCCTGCCGCTGACCGCCGCCACCGAAGGCCTG 
ATCGGTGCCGCGCAGTTCGCCCGGATGCGTCCACAGGCGATCTTCATCAACATCTCCCGTGGCCGGGTGATC 
GACGAGGCGGCCCTGATCGAGGCCCTGGCCCAGCGGCGGATCCGCGCCGCCGGCCTCGACGTGTTCGAGCGC 
GAGCCGCTGTCTCCCGACTCGCCGCTGCTGCGCCTGCCGAACGTGGTGGCCACCCCGCACATCGGCTCGGCC 
ACCGAGGAAACCCGCGAAGCCATGGCCCGCTGCGCGGTGGACAACCTGCTGGCCGCCCTCGCCGGCGAGCGG 
CCGCTGAACCTGGTCAATCCTTCGGCCTGGGCGCGACGGCGAGGCGCCTGA