ViewGene
Locus Name:
GeneID:
Location:

GeneID:2208
TrivialName: PA14_18230
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_18230
PAO1 Ortholog Locus:PA3563
Sequence Length:990
Protein Length:329
Start: 1563391
Stop: 1562402
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06951.1|AE004777_4 (AE004777) fructose transport system repressor FruR [Pseudomonas aeruginosa PAO1]
Identities = 329/329 (100%), Positives = 329/329 (100%)
Sequence:
TTGAAACTCAGTGATATCGCCCGCCTGGCCGGGGTCTCGGTGACCACCGCCAGCTACGTCATCAATGGCAAG
GCCGCCCAGCGGCGCATCAGCGCCGCCACCGTCGAGCGCGTGCTTGCCGTGGTCGAGGAACACGGCTACCAG
CCGGACCAGCAGGCCGCCGGCCTGCGCCGCGGGCAGACCCGCACCCTCGGCTTCATCCTCCCGGACCTGGAA
AACCCCAGCTACGCCCGCCTCGCCAAGCAACTCGAACAAGGCGCCCGGGCGCGCGGCTACCAGTTGCTGATC
GCCTGCTCCGACGACGAGCCGGAGACCGAGCGCCAGGTGGTCAACCTGTTCCGCGCGCGCCGCTGCGACGCG
CTGATCGTCGCCAGTTGCCTGCCGGCCGGGGATGATACCCATGCCCGGCTGGTCGCCGAAGGCCTGCCGGTG
GTGGCCATCGACCGCCAGCTCGACCCGCAGCGCTTCGCCTCGGTGATCAGCGACGACCAGGACGCCGCGCGC
CGCCTCACCGAAACCCTGTTGCAACCGGCGCCGCGCCATATCGCCCTGCTCGGCGCGCGGGCGGACCTGATC
ATCAGCCACGACCGCGCCGCCGGCTTCCGCCAGGCGCTGAAGGACTTCCGCGGCGAGGTCATCGTCGAGCAT
GCCGAGGTGTTCAGCCGCGAGTGCGGACGCCGCCTGATGGAGCAATTGCTCGAGCGCCTGGGCTACCTGCCC
GACGCCCTGGTGACCACTGCCTATGTACTCCTCGAAGGCGTCTTCGATGTGTTCCAGGCGCGCGCCGACGGT
TGGCCCGAAgGCTTGCGGGTGGCGACCTTCGGCGACACCCAGTTGCTCGACTTCGTGCCGCTGAAGGTCAAC
TCGATCTACCAGCAGCACGCGCTGATCGCCGCCAACGCCCTCGAACTGGCGCTCCGCGCGGTCGAGGAGAAC
GACTACCGGCCGGGCCTGCACGCCGTCCCCCGGCAACTCAAGCTGCGCGACTGA
Translation:
MKLSDIARLAGVSVTTASYVINGKAAQRRISAATVERVLAVVEEHGYQPDQQAAGLRRGQTRTLGFILPDLE
NPSYARLAKQLEQGARARGYQLLIACSDDEPETERQVVNLFRARRCDALIVASCLPAGDDTHARLVAEGLPV
VAIDRQLDPQRFASVISDDQDAARRLTETLLQPAPRHIALLGARADLIISHDRAAGFRQALKDFRGEVIVEH
AEVFSRECGRRLMEQLLERLGYLPDALVTTAYVLLEGVFDVFQARADGWPEGLRVATFGDTQLLDFVPLKVN
SIYQQHALIAANALELALRAVEENDYRPGLHAVPRQLKLRD*
AnnotationID:2216GeneID:2208
AnnotatorUID: diggins
Modification Date/Time: 2005-04-20 06:06:50
Gene Name:fruR
Confidence Code:2
GeneProduct:transcriptional repressor of fru operon
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1609
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66417.1|AE016269_4 (AE016777) fructose transport system repressor FruR [Pseudomonas
           putida KT2440]
          Length = 331

 Score =  425 bits (1092), Expect = e-118
 Identities = 224/328 (68%), Positives = 261/328 (79%), Gaps = 1/328 (0%)

>gb|AAO07173.1|AE016808_193 (AE016808) Transcriptional regulator [Vibrio vulnificus CMCP6]
          Length = 326

 Score =  285 bits (728), Expect = 3e-76
 Identities = 159/328 (48%), Positives = 220/328 (67%), Gaps = 3/328 (0%)

>gb|AAC73191.1| (AE000118) transcriptional repressor of fru operon and others
           [Escherichia coli K12]
          Length = 334

 Score =  272 bits (695), Expect = 2e-72
 Identities = 154/329 (46%), Positives = 206/329 (62%), Gaps = 2/329 (0%)







 
Structural Features:
COG1609, PurR, Transcriptional regulators [Transcription]
CD-Length = 333 residues,  98.2% aligned
Score =  244 bits (625), Expect = 2e-65
Identities = 111/331 (33%), Positives = 164/331 (49%), Gaps = 6/331 (1%)







   
Genomic Context:






   
Comment:


















    ReferenceID:14539




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21565




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31981




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2208_cdd.html


    		




 
URL:

















    ReferenceID:34152




  
Author/Investigator(s):
        Vartak NB, Reizer J, Reizer A, Gripp JT, Groisman EA, Wu LF, Tomich JM, Saier MH Jr.





  
Title:
        Sequence and evolution of the FruR protein of Salmonella typhimurium: a pleiotropic transcriptional regulatory protein possessing both activator and repressor functions which is homologous to the periplasmic ribose-binding protein.




  
PubMed:
        1805309


MedLine:
        




    
Source:
Res Microbiol. 1991 Nov-Dec;142(9):951-63.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1805309

















    ReferenceID:34153




  
Author/Investigator(s):
        Jahreis K, Postma PW, Lengeler JW.





  
Title:
        Nucleotide sequence of the ilvH-fruR gene region of Escherichia coli K12 and Salmonella typhimurium LT2.




  
PubMed:
        1851954


MedLine:
        




    
Source:
Mol Gen Genet. 1991 Apr;226(1-2):332-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1851954









           
Homologs By Global Alignment 

           

       



     
Gene ID:2208
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3754
                           PA3563_tr
                           translation of PA3563
                           329
                           99.99
                           99.99
                           0
                           1650.0
     

     
     
115758
                           gb|AAG06951.1|AE004777_4
                           (AE004777) fructose transport system repressor FruR [Pseudomonas aeruginosa PAO1]
                           329
                           99.69
                           99.99
                           0
                           1648.0
     

     
     
115759
                           gb|AAN66417.1|AE016269_4
                           (AE016777) fructose transport system repressor FruR [Pseudomonas putida KT2440]
                           333
                           67.26
                           78.67
                           6
                           1089.0
     

     
     
115760
                           gb|AAO54487.1|
                           (AE016859) fructose repressor FruR, putative [Pseudomonas syringae pv. tomato str. DC3000]
                           332
                           63.55
                           79.51
                           4
                           1071.0
     

     
     
115761
                           dbj|BAC62157.1|
                           (AP005086) fructose repressor [Vibrio parahaemolyticus]
                           332
                           49.09
                           69.27
                           9
                           776.0
     

     






      

          
GC ORFID: 45210How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3563Glimmer Score: 

          
Start: 3390545Stop: 3391534

          
Length: 990


          
Start Codon: TTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3563 translation of PA3563Homolog Bit Score 640.0

          
Other Homologs:  psyr_15may02_Scaffold15_revised_gene2525 (ORF: BLASTX 421.0), t_PA3563 (ORF: GLIMMER)

          
GC ORF Sequence

           
TTGAAACTCAGTGATATCGCCCGCCTGGCCGGGGTCTCGGTGACCACCGCCAGCTACGTCATCAATGGCAAG 
GCCGCCCAGCGGCGCATCAGCGCCGCCACCGTCGAGCGCGTGCTTGCCGTGGTCGAGGAACACGGCTACCAG 
CCGGACCAGCAGGCCGCCGGCCTGCGCCGCGGGCAGACCCGCACCCTCGGCTTCATCCTCCCGGACCTGGAA 
AACCCCAGCTACGCCCGCCTCGCCAAGCAACTCGAACAAGGCGCCCGGGCGCGCGGCTACCAGTTGCTGATC 
GCCTGCTCCGACGACGAGCCGGAGACCGAGCGCCAGGTGGTCAACCTGTTCCGCGCGCGCCGCTGCGACGCG 
CTGATCGTCGCCAGTTGCCTGCCGGCCGGGGATGATACCCATGCCCGGCTGGTCGCCGAAGGCCTGCCGGTG 
GTGGCCATCGACCGCCAGCTCGACCCGCAGCGCTTCGCCTCGGTGATCAGCGACGACCAGGACGCCGCGCGC 
CGCCTCACCGAAACCCTGTTGCAACCGGCGCCGCGCCATATCGCCCTGCTCGGCGCGCGGGCGGACCTGATC 
ATCAGCCACGACCGCGCCGCCGGCTTCCGCCAGGCGCTGAAGGACTTCCGCGGCGAGGTCATCGTCGAGCAT 
GCCGAGGTGTTCAGCCGCGAGTGCGGACGCCGCCTGATGGAGCAATTGCTCGAGCGCCTGGGCTACCTGCCC 
GACGCCCTGGTGACCACTGCCTATGTACTCCTCGAAGGCGTCTTCGATGTGTTCCAGGCGCGCGCCGACGGT 
TGGCCCGAAgGCTTGCGGGTGGCGACCTTCGGCGACACCCAGTTGCTCGACTTCGTGCCGCTGAAGGTCAAC 
TCGATCTACCAGCAGCACGCGCTGATCGCCGCCAACGCCCTCGAACTGGCGCTCCGCGCGGTCGAGGAGAAC 
GACTACCGGCCGGGCCTGCACGCCGTCCCCCGGCAACTCAAGCTGCGCGACTGA