ViewGene
Locus Name:
GeneID:
Location:

GeneID:2137
TrivialName: PA14_44970
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_44970
PAO1 Ortholog Locus:PA1505
Sequence Length:996
Protein Length:331
Start: 4010087
Stop: 4009092
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04894.1|AE004579_6 (AE004579) molybdopterin biosynthetic protein A2 [Pseudomonas aeruginosa PAO1]
Identities = 330/331 (99%), Positives = 330/331 (99%)
Sequence:
ATGTCCGATTCCCGCCTGGTCGATCCCTTCGGCCGTCGCATCACCTACCTGCGCCTGTCGGTGACGGATCGC
TGCGACTTCCGCTGCACCTACTGCATGAGCGAAGACATGCAGTTCCTTCCCCGCGACCAGGTCCTCAGCCTG
GAAGAACTGTACGCGGTGGCCGACGCCTTCATCGGCCTCGGCGTGCGGCGCATTCGTATCACCGGCGGCGAG
CCGCTGGTGCGCAAGGGCATCGCCGGCCTGCTGGCACGCCTGGGGCAGCGTGCGGAACTGGAAGACCTGGCG
ATCACCACCAACGGTTCGCAACTGCGCGAGCGCGCCGCCGAGCTGAAGGCCGCCGGCGTCCGCCGCCTCAAC
GTCAGCCTCGACTCGCTGCAGCGCGAACGCTTCGCCGCCTTCACCCGTAGCGATCGCCTGGAGCAGGTGCTG
GACGGCATCCAGGCGGCGCGCGAAGCCGGTTTCGAGCGGATCAAGCTGAACTGCGTGGTACAGAAGGGCCGC
AACGACGACGAGATCCTCGACCTGGTCGAGTACGCCCTGGCCAACCAGTTGGACATCAGTTTCATCGAGGAA
ATGCCGCTGGGCAGCATCACCAGCCACCGTCGCGAACTGACTCTCTGCACCAGCGACGAAGTCCGGGCGATC
ATCGAGCGCCGCTGGCCGCTGACCCCGAGCCTGGCGCGCAGCGGCGGGCCGTCGCGGTATTACCAGATCGGC
GACGAGCCCAGCCGGATCGGCTTCATCTCACCTCACAGCAATAATTTCTGCGGCGACTGCAACCGCGTGCGC
GTCACCGCCGAGGGCAAGCTGGTGCTCTGCCTCGGCCACGAGGGGGCGCTCGACCTGCGCGAACTGCTGCGC
AGCCATCCCGGCGACCGCGAGCGCCTGAGCGCGGCACTGGTGGCGGCGCTGAACCTGAAGCCGGAGCGGCAT
CACTTCGACGCCCAGGAGCAGGTCCAGGTGCTGCGTTTCATGAGCATGACCGGCGGCTGA
Translation:
MSDSRLVDPFGRRITYLRLSVTDRCDFRCTYCMSEDMQFLPRDQVLSLEELYAVADAFIGLGVRRIRITGGE
PLVRKGIAGLLARLGQRAELEDLAITTNGSQLRERAAELKAAGVRRLNVSLDSLQRERFAAFTRSDRLEQVL
DGIQAAREAGFERIKLNCVVQKGRNDDEILDLVEYALANQLDISFIEEMPLGSITSHRRELTLCTSDEVRAI
IERRWPLTPSLARSGGPSRYYQIGDEPSRIGFISPHSNNFCGDCNRVRVTAEGKLVLCLGHEGALDLRELLR
SHPGDRERLSAALVAALNLKPERHHFDAQEQVQVLRFMSMTGG*
AnnotationID:2145GeneID:2137
AnnotatorUID: diggins
Modification Date/Time: 2005-02-25 07:07:40
Gene Name:moaA2
Confidence Code:2
GeneProduct:molybdopterin biosynthetic protein A2
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG2896,pfam06463
Secondary Functional Category(ies):coenzyme metabolism
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70170.1|AE016656_5 (AE016791) molybdenum cofactor biosynthesis protein A [Pseudomonas
           putida KT2440]
          Length = 334

 Score =  390 bits (1003), Expect = e-108
 Identities = 191/327 (58%), Positives = 248/327 (75%), Gaps = 1/327 (0%)

>gb|AAO56023.1| (AE016864) molybdenum cofactor biosynthesis protein A [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 332

 Score =  372 bits (954), Expect = e-102
 Identities = 185/332 (55%), Positives = 241/332 (72%), Gaps = 1/332 (0%)

>gb|AAN57683.1|AE015904_6 (AE015904) molybdenum cofactor biosynthesis protein A, putative
           [Shewanella oneidensis MR-1]
          Length = 327

 Score =  355 bits (912), Expect = 2e-97
 Identities = 180/328 (54%), Positives = 238/328 (72%), Gaps = 2/328 (0%)









 
Structural Features:
COG2896, MoaA, Molybdenum cofactor biosynthesis enzyme 
[Coenzyme metabolism]
CD-Length = 322 residues, 100.0% aligned
Score =  359 bits (922), Expect = 3e-100
Identities = 159/328 (48%), Positives = 208/328 (63%), Gaps = 7/328 (2%)

pfam06463, Mob_synth_C, Molybdenum Cofactor Synthesis C.
CD-Length = 128 residues, 100.0% aligned
Score =  144 bits (366), Expect = 9e-36
Identities = 57/130 (43%), Positives = 78/130 (60%), Gaps = 2/130 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:4277




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21423




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37334




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2137_cdd.html


    		




 
URL:

















    ReferenceID:37942




  
Author/Investigator(s):
        Rivers SL, McNairn E, Blasco F, Giordano G, Boxer DH.





  
Title:
        Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.




  
PubMed:
        8361352


MedLine:
        




    
Source:
Mol Microbiol. 1993 Jun;8(6):1071-81.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8361352

















    ReferenceID:37943




  
Author/Investigator(s):
        Menendez C, Igloi G, Henninger H, Brandsch R.





  
Title:
        A pAO1-encoded molybdopterin cofactor gene (moaA) of Arthrobacter nicotinovorans: characterization and site-directed mutagenesis of the encoded protein.




  
PubMed:
        8588735


MedLine:
        




    
Source:
Arch Microbiol. 1995 Aug;164(2):142-51.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8588735









           
Homologs By Global Alignment 

           

       



     
Gene ID:2137
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3652
                           PA1505_tr
                           translation of PA1505
                           331
                           99.69
                           99.69
                           0
                           1680.0
     

     
     
112731
                           gb|AAG04894.1|AE004579_6
                           (AE004579) molybdopterin biosynthetic protein A2 [Pseudomonas aeruginosa PAO1]
                           331
                           99.69
                           99.69
                           0
                           1680.0
     

     
     
112734
                           gb|AAG07257.1|AE004804_5
                           (AE004804) molybdopterin biosynthetic protein A1 [Pseudomonas aeruginosa PAO1]
                           332
                           58.73
                           72.59
                           4
                           944.0
     

     
     
3653
                           PA3870_tr
                           translation of PA3870
                           332
                           58.73
                           72.59
                           4
                           944.0
     

     
     
112732
                           gb|AAN70170.1|AE016656_5
                           (AE016791) molybdenum cofactor biosynthesis protein A [Pseudomonas putida KT2440]
                           334
                           57.18
                           74.55
                           3
                           1004.0
     

     






      

          
GC ORFID: 45139How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1505Glimmer Score: 

          
Start: 943822Stop: 944817

          
Length: 996


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1505 translation of PA1505Homolog Bit Score 651.0

          
Other Homologs:  psyr_15may02_Scaffold7_revised_gene7002 (ORF: BLASTX 375.0), t_PA3870 (ORF: BLASTX 367.0), t_PA1505 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCGATTCCCGCCTGGTCGATCCCTTCGGCCGTCGCATCACCTACCTGCGCCTGTCGGTGACGGATCGC 
TGCGACTTCCGCTGCACCTACTGCATGAGCGAAGACATGCAGTTCCTTCCCCGCGACCAGGTCCTCAGCCTG 
GAAGAACTGTACGCGGTGGCCGACGCCTTCATCGGCCTCGGCGTGCGGCGCATTCGTATCACCGGCGGCGAG 
CCGCTGGTGCGCAAGGGCATCGCCGGCCTGCTGGCACGCCTGGGGCAGCGTGCGGAACTGGAAGACCTGGCG 
ATCACCACCAACGGTTCGCAACTGCGCGAGCGCGCCGCCGAGCTGAAGGCCGCCGGCGTCCGCCGCCTCAAC 
GTCAGCCTCGACTCGCTGCAGCGCGAACGCTTCGCCGCCTTCACCCGTAGCGATCGCCTGGAGCAGGTGCTG 
GACGGCATCCAGGCGGCGCGCGAAGCCGGTTTCGAGCGGATCAAGCTGAACTGCGTGGTACAGAAGGGCCGC 
AACGACGACGAGATCCTCGACCTGGTCGAGTACGCCCTGGCCAACCAGTTGGACATCAGTTTCATCGAGGAA 
ATGCCGCTGGGCAGCATCACCAGCCACCGTCGCGAACTGACTCTCTGCACCAGCGACGAAGTCCGGGCGATC 
ATCGAGCGCCGCTGGCCGCTGACCCCGAGCCTGGCGCGCAGCGGCGGGCCGTCGCGGTATTACCAGATCGGC 
GACGAGCCCAGCCGGATCGGCTTCATCTCACCTCACAGCAATAATTTCTGCGGCGACTGCAACCGCGTGCGC 
GTCACCGCCGAGGGCAAGCTGGTGCTCTGCCTCGGCCACGAGGGGGCGCTCGACCTGCGCGAACTGCTGCGC 
AGCCATCCCGGCGACCGCGAGCGCCTGAGCGCGGCACTGGTGGCGGCGCTGAACCTGAAGCCGGAGCGGCAT 
CACTTCGACGCCCAGGAGCAGGTCCAGGTGCTGCGTTTCATGAGCATGACCGGCGGCTGA