ViewGene
Locus Name:
GeneID:
Location:

GeneID:2122
TrivialName: PA14_13850
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_13850
PAO1 Ortholog Locus:PA3870
Sequence Length:990
Protein Length:329
Start: 1191307
Stop: 1192296
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07257.1|AE004804_5 (AE004804) molybdopterin biosynthetic protein A1 [Pseudomonas aeruginosa PAO1]
Identities = 329/329 (100%), Positives = 329/329 (100%)
Sequence:
ATGACCGACTGGATCGATGGCCAAGGCCGACAGATCGACTACCTGCGCCTGTCGGTCACCGACCGTTGCGAC
TTCCGCTGTGTCTACTGCATGGCCGAGGACATGCGCTTCCTGCCGCGCCAGCAGGTGCTGACCCTGGAGGAG
ATCGAGCGGGTCGCCCGGCTGTTCGTCGCCGGCGGCGTGCGCAAGCTGCGCCTGACCGGCGGCGAGCCGCTG
GTGCGGCCCGGCATCGTCGGCCTGTGCGAGCGCCTGGCGGCACTGCCGGGGTTGCGCGAACTGTGCATGACC
AGCAACGGCTCGCAACTGGTGCGCTACGCCCGGCCGTTGTACGACGCCGGCCTGTCGCGTCTCAACATCAGC
CTCGACACCCTCGATCCGCTGCGCTTCCGGGCGATCACCCGCAACGGCGAGCTGGACAAGGTGCTGGCCGGC
ATCGACGCCGCCCAGGCCGCCGGTTTCCGCCGGATCAAGCTGAACGCGGTGGTGATGAAGGGGCGCAACGCC
GATGAGGTGCCGGCGCTGGTGGACTTCGCCATCGCCCGCGGCCTGGATATCAGCTTCATCGAGGAGATGCCG
CTTGGCCAGGTCGGCCGCGAACGTGGCGAGAGCTTCTGCTCCAGCGACGAAGTACGCGCGCTGATCGCCCAG
CGCCACGCCTTGCTCGACAGCGCCGAGCAGAGCGGCGGGCCGGCGCGCTACGTGCGCCTGGTCGAGCATCCG
CAGACACGCATCGGCTTCATCTCGCCGCACTCGCACAACTTCTGCGCCACCTGCAACCGCCTGCGCCTGACC
GTCGAGGGCCGCCTGCTGCTGTGCCTCGGCCACGAGCATTCGCTCGACCTGCGCGCGCTGCTGCGCCGCCAC
CCGCTGCACGACGGGCCGTTGCTGGAAGCGATCGGCGAGGCGCTCCAGCGCAAGCCGGCGCGCCATGAATTC
AGCGCCGCCGGCGAGGTGCAGGTGCTGCGCTTCATGAACATGAGCGGCGGCTGA
Translation:
MTDWIDGQGRQIDYLRLSVTDRCDFRCVYCMAEDMRFLPRQQVLTLEEIERVARLFVAGGVRKLRLTGGEPL
VRPGIVGLCERLAALPGLRELCMTSNGSQLVRYARPLYDAGLSRLNISLDTLDPLRFRAITRNGELDKVLAG
IDAAQAAGFRRIKLNAVVMKGRNADEVPALVDFAIARGLDISFIEEMPLGQVGRERGESFCSSDEVRALIAQ
RHALLDSAEQSGGPARYVRLVEHPQTRIGFISPHSHNFCATCNRLRLTVEGRLLLCLGHEHSLDLRALLRRH
PLHDGPLLEAIGEALQRKPARHEFSAAGEVQVLRFMNMSGG*
AnnotationID:2130GeneID:2122
AnnotatorUID: diggins
Modification Date/Time: 2005-04-25 09:09:15
Gene Name:moaA1
Confidence Code:2
GeneProduct:molybdenum cofactor biosynthesis protein A
Cell Localization:()
Synonyms:moaA
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG2896,KOG2876,pfam06463
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70170.1|AE016656_5 (AE016791) molybdenum cofactor biosynthesis protein A [Pseudomonas
           putida KT2440]
          Length = 334

 Score =  447 bits (1150), Expect = e-125
 Identities = 225/326 (69%), Positives = 269/326 (82%), Gaps = 1/326 (0%)

>gb|AAN57683.1|AE015904_6 (AE015904) molybdenum cofactor biosynthesis protein A, putative
           [Shewanella oneidensis MR-1]
          Length = 327

 Score =  363 bits (932), Expect = e-100
 Identities = 184/329 (55%), Positives = 243/329 (73%), Gaps = 2/329 (0%)








 
Structural Features:
COG2896, MoaA, Molybdenum cofactor biosynthesis enzyme 
[Coenzyme metabolism]
CD-Length = 322 residues, 100.0% aligned
Score =  365 bits (938), Expect = 1e-101
Identities = 157/328 (47%), Positives = 208/328 (63%), Gaps = 7/328 (2%)

KOG2876, Molybdenum cofactor biosynthesis pathway protein 
[Coenzyme transport and metabolism]
CD-Length = 323 residues,  94.4% aligned
Score =  222 bits (566), Expect = 1e-58
Identities = 124/308 (40%), Positives = 174/308 (56%), Gaps = 5/308 (1%)

pfam06463, Mob_synth_C, Molybdenum Cofactor Synthesis C.
CD-Length = 128 residues, 100.0% aligned
Score =  144 bits (365), Expect = 2e-35
Identities = 58/130 (44%), Positives = 80/130 (61%), Gaps = 2/130 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:4247




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21393




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31694




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2122_cdd.html


    		




 
URL:

















    ReferenceID:34323




  
Author/Investigator(s):
        Rivers SL, McNairn E, Blasco F, Giordano G, Boxer DH.





  
Title:
        Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.




  
PubMed:
        8361352


MedLine:
        




    
Source:
Mol Microbiol. 1993 Jun;8(6):1071-81.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8361352









           
Homologs By Global Alignment 

           

       



     
Gene ID:2122
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3631
                           PA3870_tr
                           translation of PA3870
                           329
                           99.99
                           99.99
                           0
                           1691.0
     

     
     
111892
                           gb|AAG07257.1|AE004804_5
                           (AE004804) molybdopterin biosynthetic protein A1 [Pseudomonas aeruginosa PAO1]
                           329
                           99.99
                           99.99
                           0
                           1691.0
     

     
     
111893
                           gb|AAN70170.1|AE016656_5
                           (AE016791) molybdenum cofactor biosynthesis protein A [Pseudomonas putida KT2440]
                           334
                           67.36
                           80.53
                           5
                           1146.0
     

     
     
111894
                           gb|AAO56023.1|
                           (AE016864) molybdenum cofactor biosynthesis protein A [Pseudomonas syringae pv. tomato str. DC3000]
                           332
                           64.75
                           78.61
                           3
                           1082.0
     

     
     
111895
                           gb|AAG04894.1|AE004579_6
                           (AE004579) molybdopterin biosynthetic protein A2 [Pseudomonas aeruginosa PAO1]
                           332
                           58.73
                           72.59
                           4
                           944.0
     

     






      

          
GC ORFID: 45124How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3870Glimmer Score: 

          
Start: 3762631Stop: 3761642

          
Length: 990


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3870 translation of PA3870Homolog Bit Score 655.0

          
Other Homologs:  psyr_15may02_Scaffold7_revised_gene7002 (ORF: BLASTX 425.0), t_PA1505 (ORF: BLASTX 367.0), t_PA3870 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCGACTGGATCGATGGCCAAGGCCGACAGATCGACTACCTGCGCCTGTCGGTCACCGACCGTTGCGAC 
TTCCGCTGTGTCTACTGCATGGCCGAGGACATGCGCTTCCTGCCGCGCCAGCAGGTGCTGACCCTGGAGGAG 
ATCGAGCGGGTCGCCCGGCTGTTCGTCGCCGGCGGCGTGCGCAAGCTGCGCCTGACCGGCGGCGAGCCGCTG 
GTGCGGCCCGGCATCGTCGGCCTGTGCGAGCGCCTGGCGGCACTGCCGGGGTTGCGCGAACTGTGCATGACC 
AGCAACGGCTCGCAACTGGTGCGCTACGCCCGGCCGTTGTACGACGCCGGCCTGTCGCGTCTCAACATCAGC 
CTCGACACCCTCGATCCGCTGCGCTTCCGGGCGATCACCCGCAACGGCGAGCTGGACAAGGTGCTGGCCGGC 
ATCGACGCCGCCCAGGCCGCCGGTTTCCGCCGGATCAAGCTGAACGCGGTGGTGATGAAGGGGCGCAACGCC 
GATGAGGTGCCGGCGCTGGTGGACTTCGCCATCGCCCGCGGCCTGGATATCAGCTTCATCGAGGAGATGCCG 
CTTGGCCAGGTCGGCCGCGAACGTGGCGAGAGCTTCTGCTCCAGCGACGAAGTACGCGCGCTGATCGCCCAG 
CGCCACGCCTTGCTCGACAGCGCCGAGCAGAGCGGCGGGCCGGCGCGCTACGTGCGCCTGGTCGAGCATCCG 
CAGACACGCATCGGCTTCATCTCGCCGCACTCGCACAACTTCTGCGCCACCTGCAACCGCCTGCGCCTGACC 
GTCGAGGGCCGCCTGCTGCTGTGCCTCGGCCACGAGCATTCGCTCGACCTGCGCGCGCTGCTGCGCCGCCAC 
CCGCTGCACGACGGGCCGTTGCTGGAAGCGATCGGCGAGGCGCTCCAGCGCAAGCCGGCGCGCCATGAATTC 
AGCGCCGCCGGCGAGGTGCAGGTGCTGCGCTTCATGAACATGAGCGGCGGCTGA