ViewGene
Locus Name:
GeneID:
Location:

GeneID:2017
TrivialName: PA14_19870
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_19870
PAO1 Ortholog Locus:PA3418
Sequence Length:1026
Protein Length:341
Start: 1713500
Stop: 1714525
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06806.1|AE004763_1 (AE004763) leucine dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 341/341 (100%), Positives = 341/341 (100%)
Sequence:
ATGTTCGACATGATGGACGCGGCCCGGCTCGAGGGTCTCCACCTCGCCCAAGACCCGGCCACGGGACTCAAG
GCCATTATCGCCATCCACAGCACGCGACTCGGCCCGGCGCTGGGTGGTTGTCGCTACCTGCCTTACCCCAAC
GACGAAGCCGCCATCGGCGACGCCATCCGCCTGGCCCAGGGCATGAGCTACAAGGCGGCCCTGGCCGGGCTG
GAGCAGGGCGGCGGCAAGGCGGTGATCATCCGCCCGCCGCACCTGGACAATCGCGGCGCGCTGTTCGAGGCC
TTCGGGCGCTTCATCGAAAGCCTCGGCGGACGCTACATCACTGCGGTGGACAGCGGTACCTCCAGCGCCGAC
ATGGACTGCATCGCCCAGCAGACCCGCCACGTCACCAGCACCACCCAGGCCGGCGACCCCTCGCCGCATACC
GCCCTCGGCGTGTTCGCCGGGATTCGCGCCAGCGCCCAGGCGCGCCTCGGCAGCGACGACCTGGAAGGCCTG
CGGGTCGCGGTGCAGGGGCTCGGCCACGTCGGCTACGCATTGGCCGAGCAACTGGCGGCGGTCGGCGCCGAG
CTGCTGGTCTGCGACCTCGATCCCGGCCGGGTGCAACTGGCCGTCGAGCAGCTCGGTGCCCATCCGCTGGCG
CCGGAGGCATTGCTCTCCACCCCTTGCGACATCCTCGCGCCCTGCGGCCTGGGCGGCGTGCTCACCAGCCAG
AGCGTCAGCCAGTTGCGCTGCGCGGCGGTGGCCGGGGCGGCGAACAACCAGTTGGAGCGGCCGGAGGTCGCC
GACGAGCTGGAGGCGCGCGGCATCCTCTATGCGCCGGACTACGTGATCAACTCCGGCGGCCTGATCTACGTC
GCCCTCAAGCACCGCGGCGCCGACCCGCACAGCATCACCGCGCACCTGGCGCGGATTCCCGCGCGGCTCACC
GAGATCTATGCCCATGCCCAGGCCGACCACCAGTCGCCGGCGCGGATCGCCGACCGTCTGGCGGAACGGATT
CTCTACGGCCCGCAGTGA
Translation:
MFDMMDAARLEGLHLAQDPATGLKAIIAIHSTRLGPALGGCRYLPYPNDEAAIGDAIRLAQGMSYKAALAGL
EQGGGKAVIIRPPHLDNRGALFEAFGRFIESLGGRYITAVDSGTSSADMDCIAQQTRHVTSTTQAGDPSPHT
ALGVFAGIRASAQARLGSDDLEGLRVAVQGLGHVGYALAEQLAAVGAELLVCDLDPGRVQLAVEQLGAHPLA
PEALLSTPCDILAPCGLGGVLTSQSVSQLRCAAVAGAANNQLERPEVADELEARGILYAPDYVINSGGLIYV
ALKHRGADPHSITAHLARIPARLTEIYAHAQADHQSPARIADRLAERILYGPQ*
AnnotationID:2026GeneID:2017
AnnotatorUID: diggins
Modification Date/Time: 2005-04-18 12:12:55
Gene Name:ldh
Confidence Code:2
GeneProduct:leucine dehydrogenase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:glutamate dehydrogenase
Functional Category Confidence Code:5
COGs:COG0334
Secondary Functional Category(ies):
EC Number:1.4.1.9
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70190.1|AE016658_7 (AE016791) leucine dehydrogenase [Pseudomonas putida KT2440]
          Length = 339

 Score =  502 bits (1292), Expect = e-141
 Identities = 249/339 (73%), Positives = 288/339 (84%)

>gb|AAM25357.1| (AE013166) Glutamate dehydrogenase/leucine dehydrogenase
           [Thermoanaerobacter tengcongensis]
          Length = 355

 Score =  292 bits (747), Expect = 2e-78
 Identities = 156/337 (46%), Positives = 217/337 (64%), Gaps = 3/337 (0%)

>gb|AAM25358.1| (AE013166) Glutamate dehydrogenase/leucine dehydrogenase
           [Thermoanaerobacter tengcongensis]
          Length = 355

 Score =  283 bits (725), Expect = 8e-76
 Identities = 149/337 (44%), Positives = 213/337 (63%), Gaps = 3/337 (0%)






 
Structural Features:
COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase 
[Amino acid transport and metabolism]
CD-Length = 411 residues,  91.0% aligned
Score =  275 bits (704), Expect = 7e-75
Identities = 113/381 (29%), Positives = 148/381 (38%), Gaps = 50/381 (13%)







   
Genomic Context:






   
Comment:


















    ReferenceID:4037




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21183




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32148




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2017_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:2017
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3507
                           PA3418_tr
                           translation of PA3418
                           341
                           99.99
                           99.99
                           0
                           1738.0
     

     
     
107473
                           gb|AAG06806.1|AE004763_1
                           (AE004763) leucine dehydrogenase [Pseudomonas aeruginosa PAO1]
                           341
                           99.99
                           99.99
                           0
                           1738.0
     

     
     
107474
                           gb|AAN70190.1|AE016658_7
                           (AE016791) leucine dehydrogenase [Pseudomonas putida KT2440]
                           341
                           73.02
                           84.45
                           2
                           1292.0
     

     
     
107475
                           gb|AAC32841.1|
                           (AF075724) unknown [Legionella pneumophila]
                           360
                           45.55
                           61.38
                           22
                           810.0
     

     
     
107491
                           dbj|BAC71844.1|
                           (AP005037) putative valine dehydrogenase (NADP+) [Streptomyces avermitilis MA-4680]
                           368
                           45.38
                           56.52
                           34
                           708.0
     

     






      

          
GC ORFID: 45019How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3418Glimmer Score: 

          
Start: 3240432Stop: 3239407

          
Length: 1026


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3418 translation of PA3418Homolog Bit Score 674.0

          
Other Homologs:  t_PA3418 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTTCGACATGATGGACGCGGCCCGGCTCGAGGGTCTCCACCTCGCCCAAGACCCGGCCACGGGACTCAAG 
GCCATTATCGCCATCCACAGCACGCGACTCGGCCCGGCGCTGGGTGGTTGTCGCTACCTGCCTTACCCCAAC 
GACGAAGCCGCCATCGGCGACGCCATCCGCCTGGCCCAGGGCATGAGCTACAAGGCGGCCCTGGCCGGGCTG 
GAGCAGGGCGGCGGCAAGGCGGTGATCATCCGCCCGCCGCACCTGGACAATCGCGGCGCGCTGTTCGAGGCC 
TTCGGGCGCTTCATCGAAAGCCTCGGCGGACGCTACATCACTGCGGTGGACAGCGGTACCTCCAGCGCCGAC 
ATGGACTGCATCGCCCAGCAGACCCGCCACGTCACCAGCACCACCCAGGCCGGCGACCCCTCGCCGCATACC 
GCCCTCGGCGTGTTCGCCGGGATTCGCGCCAGCGCCCAGGCGCGCCTCGGCAGCGACGACCTGGAAGGCCTG 
CGGGTCGCGGTGCAGGGGCTCGGCCACGTCGGCTACGCATTGGCCGAGCAACTGGCGGCGGTCGGCGCCGAG 
CTGCTGGTCTGCGACCTCGATCCCGGCCGGGTGCAACTGGCCGTCGAGCAGCTCGGTGCCCATCCGCTGGCG 
CCGGAGGCATTGCTCTCCACCCCTTGCGACATCCTCGCGCCCTGCGGCCTGGGCGGCGTGCTCACCAGCCAG 
AGCGTCAGCCAGTTGCGCTGCGCGGCGGTGGCCGGGGCGGCGAACAACCAGTTGGAGCGGCCGGAGGTCGCC 
GACGAGCTGGAGGCGCGCGGCATCCTCTATGCGCCGGACTACGTGATCAACTCCGGCGGCCTGATCTACGTC 
GCCCTCAAGCACCGCGGCGCCGACCCGCACAGCATCACCGCGCACCTGGCGCGGATTCCCGCGCGGCTCACC 
GAGATCTATGCCCATGCCCAGGCCGACCACCAGTCGCCGGCGCGGATCGCCGACCGTCTGGCGGAACGGATT 
CTCTACGGCCCGCAGTGA