ViewGene
Locus Name:
GeneID:
Location:

GeneID:1976
TrivialName: PA14_47670
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_47670
PAO1 Ortholog Locus:PA1279
Sequence Length:1056
Protein Length:351
Start: 4244371
Stop: 4243316
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04668.1|AE004557_9 (AE004557) nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [Pseudomonas aeruginosa PAO1]
Identities = 345/351 (98%), Positives = 348/351 (99%)
Sequence:
ATGAGTCTGCAATGGTGGCGCGACACCTGCCGCGAGGCGGACCCGCAGATGCGCCGGCGCGCGGCCGAACGC
CAGGACCGGTTGACCAAGCCGCGCGGCTCGCTGGGCCGCCTGGAGCAGGTGGCGATCGACCTGGCGGCGTTG
CAGGGGCGCGAACGACCGAGCCTGGAGAGGCTCTGGGTGACGGTCTTCGCCGGCGACCACGGGGTAGTCGCC
GAGGGCGTCTCGGCCTATCCGCAGGCGGTCACCGGCGAGATGCTGCGCAACTTCGTCCGCGGCGGCGCGGCG
ATCAGCGTGCTGGCGCGCGAACTCGGCGCCGGCCTGGAGGTGGTCGACCTGGGCACCGCCGTCCCCCTGGAA
GCCTTGCCCGGCGTGCGCCACCTGCGCCTGGCGGCGGGTACCGCGAACTTCGTCGAGGCCCCGGCGATGGGC
GCCGAACAGTGCCTGCTGGCGCTCGAGGCCGGGCGCGAAAGCGTGCGCCGCGCCGAGCAGGCCGGCAGCCAG
CTGTTCATCGGCGGCGAGATGGGCATCGGCAATACCACCGCGGCGGCGGCCATGGCCTGCGCGCTGCTGGAT
GCGCCGGTGAGCGCGCTGGTCGGGCCGGGAACCGGGCTGGACGCCAGCGGCGTGGCGCACAAGACCGCGGTG
ATCGAGCGCGCCCTGGCCCTGCACGGCGCCCATCGCGCCGACCCCTTCGAAACCCTCCGCCGTCTCGGTGGG
CTGGAGATCGCCGCGCTGGCCGGCGCCTACCTGGCCTGCGCGCAGAAAGGCATGGTTGCCCTGGTCGACGGC
TACATCTGCAGCGTCGCGGCGCTCTGCGCGGTGCGCCTGAACCCGGCCTGCCGCGACTGGCTGCTGTTCGCC
CACAGTGGTGCCGAGCCGGGCCATCGGCATGTGCTCGAAGCCCTGGCGGCGCAACCGCTGCTCGACCTCGGC
TTGCGCCTGGGCGAGGGCAGCGGCGCGGCGCTGGCGGTGCCGCTGCTGCGCCAGGCCTGCGCGCTGCACGCG
GGGATGGCGACCTTCGCCGAAGCGGCGGTCTCGGACCGCCCGGCATGA
Translation:
MSLQWWRDTCREADPQMRRRAAERQDRLTKPRGSLGRLEQVAIDLAALQGRERPSLERLWVTVFAGDHGVVA
EGVSAYPQAVTGEMLRNFVRGGAAISVLARELGAGLEVVDLGTAVPLEALPGVRHLRLAAGTANFVEAPAMG
AEQCLLALEAGRESVRRAEQAGSQLFIGGEMGIGNTTAAAAMACALLDAPVSALVGPGTGLDASGVAHKTAV
IERALALHGAHRADPFETLRRLGGLEIAALAGAYLACAQKGMVALVDGYICSVAALCAVRLNPACRDWLLFA
HSGAEPGHRHVLEALAAQPLLDLGLRLGEGSGAALAVPLLRQACALHAGMATFAEAAVSDRPA*
AnnotationID:1985GeneID:1976
AnnotatorUID: diggins
Modification Date/Time: 2005-04-27 08:08:28
Gene Name:cobU
Confidence Code:2
GeneProduct:nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Cell Localization:()
Synonyms:cobT
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam02277,COG2038
Secondary Functional Category(ies):
EC Number:2.4.2.21
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO55235.1| (AE016861) nicotinate-nucleotide--dimethylbenzimidazole
           phosphoribosyltransferase [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 350

 Score =  493 bits (1269), Expect = e-139
 Identities = 245/351 (69%), Positives = 287/351 (81%), Gaps = 1/351 (0%)

>gb|AAN67300.1|AE016356_8 (AE016780) nicotinate-nucleotide--dimethylbenzimidazole
           phosphoribosyltransferase [Pseudomonas putida KT2440]
          Length = 351

 Score =  468 bits (1204), Expect = e-131
 Identities = 241/351 (68%), Positives = 272/351 (77%)

>gb|AAM38030.1| (AE011964) nicotinate-nucleotide-dimethylbenzimidazole
           phosphoribosyltransferase [Xanthomonas axonopodis pv.
           citri str. 306]
          Length = 348

 Score =  399 bits (1026), Expect = e-110
 Identities = 212/348 (60%), Positives = 248/348 (71%), Gaps = 1/348 (0%)






 
Structural Features:
pfam02277, DBI_PRT, Phosphoribosyltransferase.
CD-Length = 337 residues, 100.0% aligned
Score =  356 bits (916), Expect = 2e-99
Identities = 190/341 (55%), Positives = 222/341 (65%), Gaps = 4/341 (1%)

COG2038, CobT, NaMN:DMB phosphoribosyltransferase 
[Coenzyme metabolism]
CD-Length = 347 residues,  96.8% aligned
Score =  288 bits (738), Expect = 7e-79
Identities = 155/350 (44%), Positives = 191/350 (54%), Gaps = 15/350 (4%)







   
Genomic Context:






   
Comment:


















    ReferenceID:3955




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21101




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37519




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1976_cdd.html


    		




 
URL:

















    ReferenceID:38022




  
Author/Investigator(s):
        Cameron B, Blanche F, Rouyez MC, Bisch D, Famechon A, Couder M, Cauchois L, Thibaut D, Debussche L, Crouzet J.





  
Title:
        Genetic analysis, nucleotide sequence, and products of two Pseudomonas denitrificans cob genes encoding nicotinate-nucleotide: dimethylbenzimidazole phosphoribosyltransferase and cobalamin (5'-phosphate) synthase.




  
PubMed:
        1917841


MedLine:
        




    
Source:
J Bacteriol. 1991 Oct;173(19):6066-73.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1917841

















    ReferenceID:38023




  
Author/Investigator(s):
        Cameron B, Guilhot C, Blanche F, Cauchois L, Rouyez MC, Rigault S, Levy-Schil S, Crouzet J.





  
Title:
        Genetic and sequence analyses of a Pseudomonas denitrificans DNA fragment containing two cob genes.




  
PubMed:
        1917840


MedLine:
        




    
Source:
J Bacteriol. 1991 Oct;173(19):6058-65.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1917840









           
Homologs By Global Alignment 

           

       



     
Gene ID:1976
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3439
                           PA1279_tr
                           translation of PA1279
                           351
                           98.29
                           99.14
                           0
                           1754.0
     

     
     
105665
                           gb|AAG04668.1|AE004557_9
                           (AE004557) nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [Pseudomonas aeruginosa PAO1]
                           351
                           98.29
                           99.14
                           0
                           1754.0
     

     
     
105666
                           gb|AAO55235.1|
                           (AE016861) nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [Pseudomonas syringae pv. tomato str. DC3000]
                           351
                           69.80
                           81.76
                           1
                           1271.0
     

     
     
105667
                           gb|AAN67300.1|AE016356_8
                           (AE016780) nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [Pseudomonas putida KT2440]
                           351
                           68.66
                           77.49
                           0
                           1204.0
     

     
     
105668
                           emb|CAD44475.1|
                           (AJ297529) nicotinate nucleotide diethylbenzimidazole phosphoribosyltransferase [Pseudomonas stutzeri]
                           351
                           63.81
                           70.65
                           38
                           1091.0
     

     






      

          
GC ORFID: 44978How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1279Glimmer Score: 

          
Start: 709538Stop: 710593

          
Length: 1056


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1279 translation of PA1279Homolog Bit Score 680.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene1365 (ORF: BLASTX 486.0), t_PA1279 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAGTCTGCAATGGTGGCGCGACACCTGCCGCGAGGCGGACCCGCAGATGCGCCGGCGCGCGGCCGAACGC 
CAGGACCGGTTGACCAAGCCGCGCGGCTCGCTGGGCCGCCTGGAGCAGGTGGCGATCGACCTGGCGGCGTTG 
CAGGGGCGCGAACGACCGAGCCTGGAGAGGCTCTGGGTGACGGTCTTCGCCGGCGACCACGGGGTAGTCGCC 
GAGGGCGTCTCGGCCTATCCGCAGGCGGTCACCGGCGAGATGCTGCGCAACTTCGTCCGCGGCGGCGCGGCG 
ATCAGCGTGCTGGCGCGCGAACTCGGCGCCGGCCTGGAGGTGGTCGACCTGGGCACCGCCGTCCCCCTGGAA 
GCCTTGCCCGGCGTGCGCCACCTGCGCCTGGCGGCGGGTACCGCGAACTTCGTCGAGGCCCCGGCGATGGGC 
GCCGAACAGTGCCTGCTGGCGCTCGAGGCCGGGCGCGAAAGCGTGCGCCGCGCCGAGCAGGCCGGCAGCCAG 
CTGTTCATCGGCGGCGAGATGGGCATCGGCAATACCACCGCGGCGGCGGCCATGGCCTGCGCGCTGCTGGAT 
GCGCCGGTGAGCGCGCTGGTCGGGCCGGGAACCGGGCTGGACGCCAGCGGCGTGGCGCACAAGACCGCGGTG 
ATCGAGCGCGCCCTGGCCCTGCACGGCGCCCATCGCGCCGACCCCTTCGAAACCCTCCGCCGTCTCGGTGGG 
CTGGAGATCGCCGCGCTGGCCGGCGCCTACCTGGCCTGCGCGCAGAAAGGCATGGTTGCCCTGGTCGACGGC 
TACATCTGCAGCGTCGCGGCGCTCTGCGCGGTGCGCCTGAACCCGGCCTGCCGCGACTGGCTGCTGTTCGCC 
CACAGTGGTGCCGAGCCGGGCCATCGGCATGTGCTCGAAGCCCTGGCGGCGCAACCGCTGCTCGACCTCGGC 
TTGCGCCTGGGCGAGGGCAGCGGCGCGGCGCTGGCGGTGCCGCTGCTGCGCCAGGCCTGCGCGCTGCACGCG 
GGGATGGCGACCTTCGCCGAAGCGGCGGTCTCGGACCGCCCGGCATGA