ViewGene
Locus Name:
GeneID:
Location:

GeneID:1971
TrivialName: PA14_08480
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_08480
PAO1 Ortholog Locus:PA0662
Sequence Length:1035
Protein Length:344
Start: 725967
Stop: 727001
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04051.1|AE004501_3 (AE004501) N-acetyl-gamma-glutamyl-phosphate reductase [Pseudomonas aeruginosa PAO1]
Identities = 342/344 (99%), Positives = 342/344 (99%)
Sequence:
ATGATCAAGGTCGGCATCGTTGGCGGTACGGGTTATACGGGCGTGGAACTGCTGCGCCTGCTGGCGCAGCAT
CCGCAGGCCCGGGTGGAAGTGATCACTTCGCGTTCCGAGGCGGGGGTGAAGGTCGCCGACATGTACCCGAAC
CTGCGAGGTCATTATGACGACCTGCAGTTCAGCGTGCCGGACGTGCAGCGCCTCGGCGCCTGCGACGTGGTG
TTCTTCGCCACGCCGCACGGCGTGGCGCACGCGCTGGCTGGCGAACTGCTGGACGCCGGGACCCGGGTCATC
GATCTGTCCGCTGACTTCCGCCTGGCGGACGCCGAGGAGTGGGCGCGCTGGTACGGCCAGCCGCATGGCGCT
CCGGCGCTGCTCGACGAGGCTGTCTACGGCCTGCCGGAAGTGAACCGCGAGAAGATCCGCCAGGCCCGCCTG
ATCGCCGTGCCGGGTTGCTACCCGACCGCGACCCAACTGGGCCTGATCCCGCTGCTGGAGGCCGGCCTGGCC
GACGCCTCGCGGCTGATCGCCGATTGCAAGTCCGGGGTCAGCGGCGCCGGTCGGGGCGCCAAGGTTGGCTCG
CTGTTCTGCGAGGCGGGCGAAAGCATGATGGCCTACGCGGTCAAGGGGCATCGGCATCTCCCGGAAATCAGC
CAGGGCCTGTGTCGGGCCTCCGGCGGCGACGTCGGGCTGACGTTCGTACCGCACCTGACGCCAATGATCCGC
GGTATCCATGCAACCCTCTATGCCCATGTCGCGGATCGCTCGGTCGACCTCCAGGCGCTGTTCGAGAAGCGC
TACGCCGACGAACCCTTCGTCGACGTGATGCCGGCCGGCAGCCATCCGGAGACCCGCAGCGTGCGTGGCGCC
AATGTCTGCCGAATCGCCGTGCATCGCCCCCAGGGCGGCGACCTGGTGGTGGTGCTGTCGGTGATCGACAAC
CTGGTCAAGGGCGCCTCGGGTCAGGCGCTCCAGAACATGAACATCCTGTTCGGGCTGGACGAGCGCCTGGGC
CTCTCGCATGCGGCCCTGCTCCCCTGA
Translation:
MIKVGIVGGTGYTGVELLRLLAQHPQARVEVITSRSEAGVKVADMYPNLRGHYDDLQFSVPDVQRLGACDVV
FFATPHGVAHALAGELLDAGTRVIDLSADFRLADAEEWARWYGQPHGAPALLDEAVYGLPEVNREKIRQARL
IAVPGCYPTATQLGLIPLLEAGLADASRLIADCKSGVSGAGRGAKVGSLFCEAGESMMAYAVKGHRHLPEIS
QGLCRASGGDVGLTFVPHLTPMIRGIHATLYAHVADRSVDLQALFEKRYADEPFVDVMPAGSHPETRSVRGA
NVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQALQNMNILFGLDERLGLSHAALLP*
AnnotationID:1980GeneID:1971
AnnotatorUID: diggins
Modification Date/Time: 2005-03-29 18:06:01
Gene Name:argC
Confidence Code:2
GeneProduct:N-acetyl-gamma-glutamyl-phosphate reductase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:acetylglutamate semialdehyde dehydrogenase
Functional Category Confidence Code:5
COGs:COG0002
Secondary Functional Category(ies):
EC Number:1.2.1.38
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66062.1|AE016235_1 (AE016775) N-acetyl-gamma-glutamyl-phosphate reductase, putative
           [Pseudomonas putida KT2440]
          Length = 344

 Score =  621 bits (1602), Expect = e-177
 Identities = 310/344 (90%), Positives = 321/344 (93%)

>gb|AAO54146.1| (AE016858) N-acetyl-gamma-glutamyl-phosphate reductase [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 344

 Score =  600 bits (1546), Expect = e-171
 Identities = 296/344 (86%), Positives = 315/344 (91%)

>emb|CAD85393.1| (BX321861) argC; N-acetyl-gamma-glutamyl-phosphate reductase
           [Nitrosomonas europaea ATCC 19718]
          Length = 342

 Score =  461 bits (1187), Expect = e-129
 Identities = 230/344 (66%), Positives = 268/344 (77%), Gaps = 2/344 (0%)








 
Structural Features:
COG0002, ArgC, Acetylglutamate semialdehyde dehydrogenase 
[Amino acid transport and metabolism]
CD-Length = 349 residues,  99.7% aligned
Score =  451 bits (1161), Expect = 7e-128
Identities = 193/349 (55%), Positives = 239/349 (68%), Gaps = 6/349 (1%)








   
Genomic Context:






   
Comment:


















    ReferenceID:3945




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21091




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34615




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1971_cdd.html


    		




 
URL:

















    ReferenceID:35245




  
Author/Investigator(s):
        Chun JY, Lee EJ, Lee HS, Cheon CI, Min KH, Lee MS.





  
Title:
        Molecular cloning and analysis of the argC gene from Corynebacterium glutamicum.




  
PubMed:
        9818083


MedLine:
        




    
Source:
Biochem Mol Biol Int. 1998 Oct;46(3):437-47.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9818083

















    ReferenceID:35246




  
Author/Investigator(s):
        Ludovice M, Martin JF, Carrachas P, Liras P.





  
Title:
        Characterization of the Streptomyces clavuligerus argC gene encoding N-acetylglutamyl-phosphate reductase: expression in Streptomyces lividans and effect on clavulanic acid production.




  
PubMed:
        1339424


MedLine:
        




    
Source:
J Bacteriol. 1992 Jul;174(14):4606-13.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1339424

















    ReferenceID:35247




  
Author/Investigator(s):
        Smith MC, Mountain A, Baumberg S.





  
Title:
        Nucleotide sequence of the Bacillus subtilis argC gene encoding N-acetylglutamate-gamma-semialdehyde dehydrogenase.




  
PubMed:
        2117746


MedLine:
        




    
Source:
Nucleic Acids Res. 1990 Aug 11;18(15):4595.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2117746

















    ReferenceID:35248




  
Author/Investigator(s):
        Parsot C, Boyen A, Cohen GN, Glansdorff N.





  
Title:
        Nucleotide sequence of Escherichia coli argB and argC genes: comparison of N-acetylglutamate kinase and N-acetylglutamate-gamma-semialdehyde dehydrogenase with homologous and analogous enzymes.




  
PubMed:
        2851495


MedLine:
        




    
Source:
Gene. 1988 Sep 7;68(2):275-83.






    
Reference Type:Journal 







    
Data:


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1971
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3434
                           PA0662_tr
                           translation of PA0662
                           344
                           99.41
                           99.41
                           0
                           1759.0
     

     
     
105560
                           gb|AAG04051.1|AE004501_3
                           (AE004501) N-acetyl-gamma-glutamyl-phosphate reductase [Pseudomonas aeruginosa PAO1]
                           344
                           99.41
                           99.41
                           0
                           1759.0
     

     
     
105561
                           gb|AAN66062.1|AE016235_1
                           (AE016775) N-acetyl-gamma-glutamyl-phosphate reductase, putative [Pseudomonas putida KT2440]
                           344
                           90.11
                           93.31
                           0
                           1602.0
     

     
     
105562
                           gb|AAO54146.1|
                           (AE016858) N-acetyl-gamma-glutamyl-phosphate reductase [Pseudomonas syringae pv. tomato str. DC3000]
                           344
                           86.04
                           91.56
                           0
                           1546.0
     

     
     
105563
                           gb|AAQ61357.1|
                           (AE016923) N-acetyl-gamma-glutamyl-phosphate reductase [Chromobacterium violaceum ATCC 12472]
                           344
                           70.93
                           81.39
                           2
                           1269.0
     

     






      

          
GC ORFID: 44973How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0662Glimmer Score: 

          
Start: 6527310Stop: 6528344

          
Length: 1035


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA0662 translation of PA0662Homolog Bit Score 682.0

          
Other Homologs:  psyr_15may02_Scaffold14_revised_gene2367 (ORF: BLASTX 608.0), t_PA0662 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGATCAAGGTCGGCATCGTTGGCGGTACGGGTTATACGGGCGTGGAACTGCTGCGCCTGCTGGCGCAGCAT 
CCGCAGGCCCGGGTGGAAGTGATCACTTCGCGTTCCGAGGCGGGGGTGAAGGTCGCCGACATGTACCCGAAC 
CTGCGAGGTCATTATGACGACCTGCAGTTCAGCGTGCCGGACGTGCAGCGCCTCGGCGCCTGCGACGTGGTG 
TTCTTCGCCACGCCGCACGGCGTGGCGCACGCGCTGGCTGGCGAACTGCTGGACGCCGGGACCCGGGTCATC 
GATCTGTCCGCTGACTTCCGCCTGGCGGACGCCGAGGAGTGGGCGCGCTGGTACGGCCAGCCGCATGGCGCT 
CCGGCGCTGCTCGACGAGGCTGTCTACGGCCTGCCGGAAGTGAACCGCGAGAAGATCCGCCAGGCCCGCCTG 
ATCGCCGTGCCGGGTTGCTACCCGACCGCGACCCAACTGGGCCTGATCCCGCTGCTGGAGGCCGGCCTGGCC 
GACGCCTCGCGGCTGATCGCCGATTGCAAGTCCGGGGTCAGCGGCGCCGGTCGGGGCGCCAAGGTTGGCTCG 
CTGTTCTGCGAGGCGGGCGAAAGCATGATGGCCTACGCGGTCAAGGGGCATCGGCATCTCCCGGAAATCAGC 
CAGGGCCTGTGTCGGGCCTCCGGCGGCGACGTCGGGCTGACGTTCGTACCGCACCTGACGCCAATGATCCGC 
GGTATCCATGCAACCCTCTATGCCCATGTCGCGGATCGCTCGGTCGACCTCCAGGCGCTGTTCGAGAAGCGC 
TACGCCGACGAACCCTTCGTCGACGTGATGCCGGCCGGCAGCCATCCGGAGACCCGCAGCGTGCGTGGCGCC 
AATGTCTGCCGAATCGCCGTGCATCGCCCCCAGGGCGGCGACCTGGTGGTGGTGCTGTCGGTGATCGACAAC 
CTGGTCAAGGGCGCCTCGGGTCAGGCGCTCCAGAACATGAACATCCTGTTCGGGCTGGACGAGCGCCTGGGC 
CTCTCGCATGCGGCCCTGCTCCCCTGA