ViewGene
Locus Name:
GeneID:
Location:

GeneID:1970
TrivialName: PA14_61580
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_61580
PAO1 Ortholog Locus:PA4655
Sequence Length:1023
Protein Length:340
Start: 5495502
Stop: 5494480
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08042.1|AE004879_8 (AE004879) ferrochelatase [Pseudomonas aeruginosa PAO1]
Identities = 338/340 (99%), Positives = 338/340 (99%)
Sequence:
ATGACCGAGAATGCCCTGCTGTTGCTCAACCTGGGCTCCCCGGATTCGACCCGGGTGGAGGATGTCCGCCGC
TATCTCGACCAGTTCCTCATGGATCCCTACGTGGTCGACCTGCCCTGGCCGCTGCGGCGCCTGCTGGTGTCG
CTGATCCTGATCAAGCGTCCGGCCGAATCGGCGCACGCCTACAGCTCGATCTGGTGGGACGAAGGGTCGCCA
CTGATCGTCCTCAGTCGTCGCCTGCAGGAAGCGATGAAGCCGCACTGGCCGCATGGACCGGTGGAACTGGCG
ATGCGCTACGGCCAGCCGGCCATCGAGAAGGTCCTGCTCGACCTGGCGCGCCGCGGTATCCGGCGGGTGACC
CTGGCGCCGCTGTATCCACAGTTCGCCGACAGCACCACGACCACCGCCGAACAAGAGGTGCGCCGGGTGATC
GCCGCCCATCGCCTGGAGCTGGAGGTCAGCACGCTGCCGCCGTTCTACGACCAGCCGGTCTACCTCGATGCC
CTGGTGGAAAGCGTGCGTCCGTACCTGCAGCAGCCCCACGACCATCTGTTGCTGAGCTTCCATGGCTTGCCC
GAGCGGCACATCCGCAAGCTGGTGAAGGATCCTGCCCACGACCTGCTGGCCGAGAACAGCCGCAACGTCAGC
CCCGAAGCCCTCGCCCTCTGCTACCGCAGCCAGTGCCTGCGCACCGCCGAGGCCTTCGCCGAGCGCGCCGGC
CTGGAGCAGGGGCGCTGGTCGGTGTCGTTCCAGTCGCGCCTGGGGCGCGCCAAGTGGATCGAGCCCTATACC
GACGCCAAGCTCGACGAACTGGTGCAGCGTGGGGTGAAGCGCCTGCTGGTGATGTGCCCGGCGTTCGTCGCC
GACTGCATCGAGACTCTGGAGGAAATCGGCATGCGCGGCCGCGAGCAGTTCATCAGCGCCGGCGGCGAGGAC
CTGGTGCTGATTCCCTGCCTCAACGACCACCCCGCCTGGGTCGGCGCCCTGGGCGAGATGAGCGGGCGCTTG
GCCAGGCCGCTCTGA
Translation:
MTENALLLLNLGSPDSTRVEDVRRYLDQFLMDPYVVDLPWPLRRLLVSLILIKRPAESAHAYSSIWWDEGSP
LIVLSRRLQEAMKPHWPHGPVELAMRYGQPAIEKVLLDLARRGIRRVTLAPLYPQFADSTTTTAEQEVRRVI
AAHRLELEVSTLPPFYDQPVYLDALVESVRPYLQQPHDHLLLSFHGLPERHIRKLVKDPAHDLLAENSRNVS
PEALALCYRSQCLRTAEAFAERAGLEQGRWSVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVA
DCIETLEEIGMRGREQFISAGGEDLVLIPCLNDHPAWVGALGEMSGRLARPL*
AnnotationID:1979GeneID:1970
AnnotatorUID: diggins
Modification Date/Time: 2005-04-26 20:08:04
Gene Name:hemH
Confidence Code:2
GeneProduct:ferrochelatase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam00762
Secondary Functional Category(ies):
EC Number:4.99.1.1
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66369.1|AE016265_3 (AE016776) ferrochelatase [Pseudomonas putida KT2440]
          Length = 338

 Score =  480 bits (1236), Expect = e-135
 Identities = 225/334 (67%), Positives = 275/334 (82%), Gaps = 2/334 (0%)

>gb|AAO54657.1| (AE016859) ferrochelatase [Pseudomonas syringae pv. tomato str.
           DC3000]
          Length = 340

 Score =  477 bits (1227), Expect = e-134
 Identities = 227/335 (67%), Positives = 273/335 (81%)

>gb|AAG31804.1|AF314196_1 (AF314196) ferrochelatase [Pseudomonas fluorescens]
          Length = 340

 Score =  467 bits (1201), Expect = e-131
 Identities = 231/337 (68%), Positives = 264/337 (78%), Gaps = 4/337 (1%)








 
Structural Features:
pfam00762, Ferrochelatase.
CD-Length = 316 residues,  97.8% aligned
Score =  233 bits (596), Expect = 2e-62
Identities = 110/337 (32%), Positives = 171/337 (50%), Gaps = 37/337 (10%)






   
Genomic Context:






   
Comment:


















    ReferenceID:3943




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21089




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36549




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1970_cdd.html


    		




 
URL:

















    ReferenceID:36595




  
Author/Investigator(s):
        Kanazireva E, Biel AJ.





  
Title:
        Nucleotide sequence of the Rhodobacter capsulatus hemH gene.




  
PubMed:
        8621079


MedLine:
        




    
Source:
Gene. 1996 Apr 17;170(1):149-50.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8621079

















    ReferenceID:36596




  
Author/Investigator(s):
        Hansson M, Hederstedt L.





  
Title:
        Cloning and characterization of the Bacillus subtilis hemEHY gene cluster, which encodes protoheme IX biosynthetic enzymes.




  
PubMed:
        1459957


MedLine:
        




    
Source:
J Bacteriol. 1992 Dec;174(24):8081-93.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1459957









           
Homologs By Global Alignment 

           

       



     
Gene ID:1970
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3433
                           PA4655_tr
                           translation of PA4655
                           340
                           99.41
                           99.41
                           0
                           1759.0
     

     
     
105552
                           gb|AAG08042.1|AE004879_8
                           (AE004879) ferrochelatase [Pseudomonas aeruginosa PAO1]
                           340
                           99.41
                           99.41
                           0
                           1759.0
     

     
     
105555
                           gb|AAG31804.1|AF314196_1
                           (AF314196) ferrochelatase [Pseudomonas fluorescens]
                           344
                           68.02
                           77.61
                           8
                           1204.0
     

     
     
105554
                           gb|AAO54657.1|
                           (AE016859) ferrochelatase [Pseudomonas syringae pv. tomato str. DC3000]
                           344
                           67.15
                           80.81
                           8
                           1230.0
     

     
     
105553
                           gb|AAN66369.1|AE016265_3
                           (AE016776) ferrochelatase [Pseudomonas putida KT2440]
                           342
                           65.78
                           80.70
                           6
                           1238.0
     

     






      

          
GC ORFID: 44972How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4655Glimmer Score: 

          
Start: 4759182Stop: 4758160

          
Length: 1023


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4655 translation of PA4655Homolog Bit Score 682.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4305 (ORF: BLASTX 482.0), t_PA4655 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCGAGAATGCCCTGCTGTTGCTCAACCTGGGCTCCCCGGATTCGACCCGGGTGGAGGATGTCCGCCGC 
TATCTCGACCAGTTCCTCATGGATCCCTACGTGGTCGACCTGCCCTGGCCGCTGCGGCGCCTGCTGGTGTCG 
CTGATCCTGATCAAGCGTCCGGCCGAATCGGCGCACGCCTACAGCTCGATCTGGTGGGACGAAGGGTCGCCA 
CTGATCGTCCTCAGTCGTCGCCTGCAGGAAGCGATGAAGCCGCACTGGCCGCATGGACCGGTGGAACTGGCG 
ATGCGCTACGGCCAGCCGGCCATCGAGAAGGTCCTGCTCGACCTGGCGCGCCGCGGTATCCGGCGGGTGACC 
CTGGCGCCGCTGTATCCACAGTTCGCCGACAGCACCACGACCACCGCCGAACAAGAGGTGCGCCGGGTGATC 
GCCGCCCATCGCCTGGAGCTGGAGGTCAGCACGCTGCCGCCGTTCTACGACCAGCCGGTCTACCTCGATGCC 
CTGGTGGAAAGCGTGCGTCCGTACCTGCAGCAGCCCCACGACCATCTGTTGCTGAGCTTCCATGGCTTGCCC 
GAGCGGCACATCCGCAAGCTGGTGAAGGATCCTGCCCACGACCTGCTGGCCGAGAACAGCCGCAACGTCAGC 
CCCGAAGCCCTCGCCCTCTGCTACCGCAGCCAGTGCCTGCGCACCGCCGAGGCCTTCGCCGAGCGCGCCGGC 
CTGGAGCAGGGGCGCTGGTCGGTGTCGTTCCAGTCGCGCCTGGGGCGCGCCAAGTGGATCGAGCCCTATACC 
GACGCCAAGCTCGACGAACTGGTGCAGCGTGGGGTGAAGCGCCTGCTGGTGATGTGCCCGGCGTTCGTCGCC 
GACTGCATCGAGACTCTGGAGGAAATCGGCATGCGCGGCCGCGAGCAGTTCATCAGCGCCGGCGGCGAGGAC 
CTGGTGCTGATTCCCTGCCTCAACGACCACCCCGCCTGGGTCGGCGCCCTGGGCGAGATGAGCGGGCGCTTG 
GCCAGGCCGCTCTGA