ViewGene
Locus Name:
GeneID:
Location:

GeneID:1965
TrivialName: PA14_23530
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23530
PAO1 Ortholog Locus:PA3136
Sequence Length:1068
Protein Length:355
Start: 2050360
Stop: 2049293
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06524.1|AE004737_10 (AE004737) probable secretion protein [Pseudomonas aeruginosa PAO1]
Identities = 354/355 (99%), Positives = 355/355 (100%)
Sequence:
TTGGCCGAATTTTGCCGACGGAACACTCCACCCATGCCCGCCCAACTCAAACGTCGCCTGACCGTCTTCCTG
GTGGCCGTCGGCCTGATCGCCCTGGCCTTCTTCCTCCACTGGTGGTTCATCGGCCGCCACGTGGAAAGCACC
GACAACGCCTACGTCCAGGGCGAGATCACGCGGGTGGCCAGCCAGTTGGGCGCGCGGGTCGAGGAAGTCCTG
GTGCGCGACAACCAGCACGTGGACAAGGGGCAGCTACTGGTACGCCTGGAAGACGCCGACTTCAAGCTCGCC
GTCGAGCGCGCCCAGGCCGCGCTGGCCACCCGCGAGGCGGAACTGGCCCAGGCGCGCAGCAAGCTGGTGCAG
CAGGGCAGCCTGATCGCCGCCAGCGCCGCCGACGTCAACGCCAGCCAGGCAACCCTCGGCCGCGCACAGATC
GACCTGAACCGCGCCGAAGCCCTGCGCAAGCCCGGCTACGTTTCCGAGGAACGGGTCACCACCCTCACCGCC
GACAACCACGTGGCCCGCTCGCAACTGGCCAAGGCCCGCGCCGACCTCGAGGCACAACGCGTCCAGCGCGAC
ACCCTGGGCGCCGAGATCAAGCGCCTGGAAGCGCAGATCGCCAGCGCCCGCACCGAACTGGCGCAAGCCGAA
ATCAACCTGTCACGCACCCTGATCCATTCGCCGATCAACGGCCTGGTCGGCCAGCGCAGCGCACGCAACGGT
CAGTACGTGCAGGTTGGTACCCATTTGCTGTCGCTGGTGCCGGACGAAGACATCTGGGTCCAGGCCAACTTC
AAGGAGACCCAGGTCGGCCGCATGCGCGACGGGCAGAAGGCGCGCCTGACCTTCGACGCCTTCCCCGACACG
CCTATCGACGGCCGCATCGATAGCCTGTTCGCCGCTTCCGGCGCGCAGTTCAGCCTGCTGCCACCGGACAAC
GCCACCGGAAACTTCACCAAGGTGGTGCAACGCATCCCGGTGAAGATCGTGTTCGAGGCCGACAACCCGTTG
CATGGCCGCATCCGCCCCGGCATGTCCGTCGAAGCCGAGGTCGAGCTCCGTGACCGCTGA
Translation:
MAEFCRRNTPPMPAQLKRRLTVFLVAVGLIALAFFLHWWFIGRHVESTDNAYVQGEITRVASQLGARVEEVL
VRDNQHVDKGQLLVRLEDADFKLAVERAQAALATREAELAQARSKLVQQGSLIAASAADVNASQATLGRAQI
DLNRAEALRKPGYVSEERVTTLTADNHVARSQLAKARADLEAQRVQRDTLGAEIKRLEAQIASARTELAQAE
INLSRTLIHSPINGLVGQRSARNGQYVQVGTHLLSLVPDEDIWVQANFKETQVGRMRDGQKARLTFDAFPDT
PIDGRIDSLFAASGAQFSLLPPDNATGNFTKVVQRIPVKIVFEADNPLHGRIRPGMSVEAEVELRDR*
AnnotationID:1974GeneID:1965
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 09:09:07
Gene Name:
Confidence Code:3
GeneProduct:putative secretion protein
Cell Localization:()
Synonyms:mdr
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(27) Transport of small molecules
Alternate Gene Product Name:putative multidrug resistance protein
Functional Category Confidence Code:5
COGs:pfam00529,COG1566
Secondary Functional Category(ies):protein secretion/export apparatus
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67591.1|AE016388_11 (AE016781) HlyD family secretion protein [Pseudomonas putida
           KT2440]
          Length = 387

 Score =  506 bits (1304), Expect = e-143
 Identities = 255/343 (74%), Positives = 298/343 (86%)

>dbj|BAB49683.1| (AP003000) probable secretion protein [Mesorhizobium loti]
          Length = 367

 Score =  261 bits (666), Expect = 6e-69
 Identities = 141/343 (41%), Positives = 207/343 (60%), Gaps = 2/343 (0%)








 
Structural Features:
pfam00529, HlyD, HlyD family secretion protein.
CD-Length = 309 residues,  94.5% aligned
Score = 99.0 bits (246), Expect = 7e-22
Identities = 86/295 (29%), Positives = 132/295 (44%), Gaps = 21/295 (7%)

COG1566, EmrA, Multidrug resistance efflux pump 
[Defense mechanisms]
CD-Length = 352 residues,  97.2% aligned
Score =  306 bits (785), Expect = 2e-84
Identities = 137/346 (39%), Positives = 203/346 (58%), Gaps = 10/346 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14469




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21079




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32386




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1965_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1965
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3427
                           PA3136_tr
                           translation of PA3136
                           355
                           99.71
                           99.99
                           0
                           1762.0
     

     
     
105491
                           gb|AAG06524.1|AE004737_10
                           (AE004737) probable secretion protein [Pseudomonas aeruginosa PAO1]
                           355
                           99.43
                           99.99
                           0
                           1760.0
     

     
     
105492
                           gb|AAD33771.1|AF139107_1
                           (AF139107) hypothetical multidrug resistance protein [Pseudomonas aeruginosa]
                           388
                           73.19
                           73.19
                           93
                           1393.0
     

     
     
105493
                           gb|AAN67591.1|AE016388_11
                           (AE016781) HlyD family secretion protein [Pseudomonas putida KT2440]
                           387
                           65.89
                           77.26
                           32
                           1294.0
     

     
     
3428
                           PA1237_tr
                           translation of PA1237
                           384
                           39.58
                           53.64
                           30
                           587.0
     

     






      

          
GC ORFID: 44967How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3136Glimmer Score: 

          
Start: 2903571Stop: 2904638

          
Length: 1068


          
Start Codon: TTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3136 translation of PA3136Homolog Bit Score 683.0

          
Other Homologs:  t_PA3136 (ORF: GLIMMER)

          
GC ORF Sequence

           
TTGGCCGAATTTTGCCGACGGAACACTCCACCCATGCCCGCCCAACTCAAACGTCGCCTGACCGTCTTCCTG 
GTGGCCGTCGGCCTGATCGCCCTGGCCTTCTTCCTCCACTGGTGGTTCATCGGCCGCCACGTGGAAAGCACC 
GACAACGCCTACGTCCAGGGCGAGATCACGCGGGTGGCCAGCCAGTTGGGCGCGCGGGTCGAGGAAGTCCTG 
GTGCGCGACAACCAGCACGTGGACAAGGGGCAGCTACTGGTACGCCTGGAAGACGCCGACTTCAAGCTCGCC 
GTCGAGCGCGCCCAGGCCGCGCTGGCCACCCGCGAGGCGGAACTGGCCCAGGCGCGCAGCAAGCTGGTGCAG 
CAGGGCAGCCTGATCGCCGCCAGCGCCGCCGACGTCAACGCCAGCCAGGCAACCCTCGGCCGCGCACAGATC 
GACCTGAACCGCGCCGAAGCCCTGCGCAAGCCCGGCTACGTTTCCGAGGAACGGGTCACCACCCTCACCGCC 
GACAACCACGTGGCCCGCTCGCAACTGGCCAAGGCCCGCGCCGACCTCGAGGCACAACGCGTCCAGCGCGAC 
ACCCTGGGCGCCGAGATCAAGCGCCTGGAAGCGCAGATCGCCAGCGCCCGCACCGAACTGGCGCAAGCCGAA 
ATCAACCTGTCACGCACCCTGATCCATTCGCCGATCAACGGCCTGGTCGGCCAGCGCAGCGCACGCAACGGT 
CAGTACGTGCAGGTTGGTACCCATTTGCTGTCGCTGGTGCCGGACGAAGACATCTGGGTCCAGGCCAACTTC 
AAGGAGACCCAGGTCGGCCGCATGCGCGACGGGCAGAAGGCGCGCCTGACCTTCGACGCCTTCCCCGACACG 
CCTATCGACGGCCGCATCGATAGCCTGTTCGCCGCTTCCGGCGCGCAGTTCAGCCTGCTGCCACCGGACAAC 
GCCACCGGAAACTTCACCAAGGTGGTGCAACGCATCCCGGTGAAGATCGTGTTCGAGGCCGACAACCCGTTG 
CATGGCCGCATCCGCCCCGGCATGTCCGTCGAAGCCGAGGTCGAGCTCCGTGACCGCTGA