ViewGene
Locus Name:
GeneID:
Location:

GeneID:1869
TrivialName: PA14_07170
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_07170
PAO1 Ortholog Locus:PA0551
Sequence Length:1062
Protein Length:353
Start: 620189
Stop: 621250
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG03940.1|AE004491_7 (AE004491) D-erythrose 4-phosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 353/353 (100%), Positives = 353/353 (100%)
Sequence:
ATGTCCACCCCGCCTTTTCGCGTCGCGCTCAATGGCTATGGCCGTATCGGCCGCTGCGTCCTGCGCGCGCTG
CACGAGCGCCCGGAGCAACTGGGCTTCGAGATCGTCGCGCTGAACGACCTGGCCGACCAGGCCAGCGTCGAG
TACCTGACCCGCTTCGACTCCACCCATGGCCGCTTTCCCGGCGAAGTGAAGGTCGACGGCGACTGCCTGCAC
ATCAACGGCGATTGCGTGAAGGTGCTGCGCAGCCCGACTCCGGAAGCCATCGACTGGCAGGCGCTGCGGGTC
GACCTGGTGCTGGAGTGCTCCGGCCAGTACACCAATCGCGCCCAGGCCGAGCGTTTCCTCCGCGCCGGCGCG
CCGCGGGTGCTGTTCTCGCAGCCGATGGCGAGCGAGGCGGACATCGACGCCACCATCGTCTATGGGGTCAAC
CAGCAGGACCTCAGCGGCCGCGAAACGCTGGTCTCCAACGCCTCCTGCACGACCAATTGCGGGGTGCCGCTG
CTCAAGCTGCTGAACGAGGCGATCGGCCTGGAATACGTGTCGATCACCACCATCCACTCGGCGATGAACGAC
CAGCCGGTGATCGACGCCTACCACCATGAGGACCTGCGCCGTACCCGTTCGGCGTTCCAGTCGGTGATCCCG
GTGTCCACCGGTCTGGCGCGCGGCATCGAACGCCTGTTGCCGGAACTTGCCGGGCGCATCCAGGCCAAAGCC
ATACGCGTGCCCACGGTGAACGTCTCGGCGCTGGACATCACCCTGCAGACTTCCCGCGACACCTCCGCCGCC
GAGATCAACCGGGTGCTTCGCGAGGCCGCCGAAAGCGGCCCGCTGCGCGGACTGCTGGCTTATACCGAGCTG
CCGCACGCCAGTTGCGATTTCAACCACGACCCCCATTCGGCCATCGTCGATGGCAGCCAGACCCGCGTTTCC
GGGCCTCGCCTGGTCAACCTGCTGGCCTGGTTCGACAACGAATGGGGATTCGCCAACCGTATGCTCGACGTC
GCCGGACACTACCTGCGCGCCGCCGTGCCTGATCAACAAGTACCCAAGGACTGA
Translation:
MSTPPFRVALNGYGRIGRCVLRALHERPEQLGFEIVALNDLADQASVEYLTRFDSTHGRFPGEVKVDGDCLH
INGDCVKVLRSPTPEAIDWQALRVDLVLECSGQYTNRAQAERFLRAGAPRVLFSQPMASEADIDATIVYGVN
QQDLSGRETLVSNASCTTNCGVPLLKLLNEAIGLEYVSITTIHSAMNDQPVIDAYHHEDLRRTRSAFQSVIP
VSTGLARGIERLLPELAGRIQAKAIRVPTVNVSALDITLQTSRDTSAAEINRVLREAAESGPLRGLLAYTEL
PHASCDFNHDPHSAIVDGSQTRVSGPRLVNLLAWFDNEWGFANRMLDVAGHYLRAAVPDQQVPKD*
AnnotationID:1878GeneID:1869
AnnotatorUID: diggins
Modification Date/Time: 2005-03-28 18:06:17
Gene Name:epd
Confidence Code:2
GeneProduct:D-erythrose 4-phosphate dehydrogenase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0057,pfam02800,pfam00044
Secondary Functional Category(ies):carbon compond metabolism
EC Number:1.2.1.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70531.1|AE016695_5 (AE016792) D-erythrose-4-phosphate dehydrogenase [Pseudomonas
           putida KT2440]
          Length = 352

 Score =  598 bits (1541), Expect = e-170
 Identities = 292/342 (85%), Positives = 313/342 (91%)

>gb|AAO53930.1| (AE016857) D-erythrose 4-phosphate dehydrogenase [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 347

 Score =  570 bits (1468), Expect = e-162
 Identities = 277/340 (81%), Positives = 306/340 (90%)

>gb|AAM86859.1|AE013932_2 (AE013932) D-erythrose 4-phosphate dehydrogenase [Yersinia pestis
           KIM]
          Length = 338

 Score =  354 bits (908), Expect = 5e-97
 Identities = 171/329 (51%), Positives = 238/329 (72%), Gaps = 4/329 (1%)







 
Structural Features:
COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/
erythrose-4-phosphate dehydrogenase 
[Carbohydrate transport and metabolism]
CD-Length = 335 residues,  97.6% aligned
Score =  406 bits (1046), Expect = 1e-114
Identities = 161/334 (48%), Positives = 223/334 (66%), Gaps = 8/334 (2%)

pfam02800, Gp_dh_C, Glyceraldehyde 3-phosphate dehydrogenase, 
C-terminal domain. 
CD-Length = 162 residues, 100.0% aligned
Score =  194 bits (494), Expect = 1e-50
Identities = 77/163 (47%), Positives = 106/163 (65%), Gaps = 1/163 (0%)

pfam00044, Gp_dh_N, Glyceraldehyde 3-phosphate dehydrogenase, 
NAD binding domain.
CD-Length = 151 residues, 100.0% aligned
Score =  158 bits (402), Expect = 8e-40
Identities = 68/158 (43%), Positives = 95/158 (60%), Gaps = 9/158 (5%)







   
Genomic Context:






   
Comment:


















    ReferenceID:3741




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20888




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33864




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1869_cdd.html


    		




 
URL:

















    ReferenceID:35292




  
Author/Investigator(s):
        Carroll PA, Zhao G, Boyko SA, Winkler ME, Calderwood SB.





  
Title:
        Identification, sequencing, and enzymatic activity of the erythrose-4-phosphate dehydrogenase gene of Vibrio cholerae.




  
PubMed:
        8982014


MedLine:
        




    
Source:
J Bacteriol. 1997 Jan;179(1):293-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8982014









           
Homologs By Global Alignment 

           

       



     
Gene ID:1869
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3304
                           PA0551_tr
                           translation of PA0551
                           353
                           99.99
                           99.99
                           0
                           1823.0
     

     
     
102572
                           gb|AAG03940.1|AE004491_7
                           (AE004491) D-erythrose 4-phosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
                           353
                           99.99
                           99.99
                           0
                           1823.0
     

     
     
102573
                           gb|AAN70531.1|AE016695_5
                           (AE016792) D-erythrose-4-phosphate dehydrogenase [Pseudomonas putida KT2440]
                           354
                           83.05
                           89.54
                           3
                           1537.0
     

     
     
102574
                           gb|AAO53930.1|
                           (AE016857) D-erythrose 4-phosphate dehydrogenase [Pseudomonas syringae pv. tomato str. DC3000]
                           354
                           79.37
                           87.57
                           8
                           1468.0
     

     
     
102589
                           gb|AAN54005.1|AE015538_2
                           (AE015538) D-erythrose-4-phosphate dehydrogenase [Shewanella oneidensis MR-1]
                           354
                           50.28
                           67.51
                           17
                           887.0
     

     






      

          
GC ORFID: 44871How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0551Glimmer Score: 

          
Start: 6421531Stop: 6422592

          
Length: 1062


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA0551 translation of PA0551Homolog Bit Score 706.0

          
Other Homologs:  psyr_15may02_Scaffold6_revised_gene6572 (ORF: BLASTX 569.0), t_PA3195 (ORF: BLASTX 322.0), psyr_15may02_Scaffold3_revised_gene4954 (ORF: BLASTX 293.0), t_PA0551 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCACCCCGCCTTTTCGCGTCGCGCTCAATGGCTATGGCCGTATCGGCCGCTGCGTCCTGCGCGCGCTG 
CACGAGCGCCCGGAGCAACTGGGCTTCGAGATCGTCGCGCTGAACGACCTGGCCGACCAGGCCAGCGTCGAG 
TACCTGACCCGCTTCGACTCCACCCATGGCCGCTTTCCCGGCGAAGTGAAGGTCGACGGCGACTGCCTGCAC 
ATCAACGGCGATTGCGTGAAGGTGCTGCGCAGCCCGACTCCGGAAGCCATCGACTGGCAGGCGCTGCGGGTC 
GACCTGGTGCTGGAGTGCTCCGGCCAGTACACCAATCGCGCCCAGGCCGAGCGTTTCCTCCGCGCCGGCGCG 
CCGCGGGTGCTGTTCTCGCAGCCGATGGCGAGCGAGGCGGACATCGACGCCACCATCGTCTATGGGGTCAAC 
CAGCAGGACCTCAGCGGCCGCGAAACGCTGGTCTCCAACGCCTCCTGCACGACCAATTGCGGGGTGCCGCTG 
CTCAAGCTGCTGAACGAGGCGATCGGCCTGGAATACGTGTCGATCACCACCATCCACTCGGCGATGAACGAC 
CAGCCGGTGATCGACGCCTACCACCATGAGGACCTGCGCCGTACCCGTTCGGCGTTCCAGTCGGTGATCCCG 
GTGTCCACCGGTCTGGCGCGCGGCATCGAACGCCTGTTGCCGGAACTTGCCGGGCGCATCCAGGCCAAAGCC 
ATACGCGTGCCCACGGTGAACGTCTCGGCGCTGGACATCACCCTGCAGACTTCCCGCGACACCTCCGCCGCC 
GAGATCAACCGGGTGCTTCGCGAGGCCGCCGAAAGCGGCCCGCTGCGCGGACTGCTGGCTTATACCGAGCTG 
CCGCACGCCAGTTGCGATTTCAACCACGACCCCCATTCGGCCATCGTCGATGGCAGCCAGACCCGCGTTTCC 
GGGCCTCGCCTGGTCAACCTGCTGGCCTGGTTCGACAACGAATGGGGATTCGCCAACCGTATGCTCGACGTC 
GCCGGACACTACCTGCGCGCCGCCGTGCCTGATCAACAAGTACCCAAGGACTGA