ViewGene
Locus Name:
GeneID:
Location:

GeneID:1840
TrivialName: PA14_56880
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_56880
PAO1 Ortholog Locus:PA4374
Sequence Length:1131
Protein Length:376
Start: 5067018
Stop: 5068148
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07762.1|AE004853_5 (AE004853) probable RND efflux membrane fusion protein precursor [Pseudomonas aeruginosa PAO1]
Identities = 374/376 (99%), Positives = 375/376 (99%)
Sequence:
ATGTTGCTCCGCCGCATGTTGATCATGCTCGCCGCGGTGATCGCCGTGGTGGCGATTCTCGCCGGCTACAAG
GTCTACTCCATCCGTCAGCAGATCGCCCTTTTCAGCGCACCGAAACCGCCGATCAGCGTGACCGCCAGCCTG
GCCGAAAAGCGTCCCTGGCAGAGCCGCCTGCCAGCCATCGGCAGCCTCAAGGCATTCCAGGGCGTGACCCTC
ACCGCCGAAGTCTCCGGCACGGTACGCGACGTACTGTTCCTTTCCGGCGACCAGGTGAAGCTGGACCAACCG
CTGATCCAGCTGGAAAGCGACGTCGAGGAAGCCACCCTGCGCACTGCCGAGGCCGATCTCGGCCTGGCCAGG
GCCGAGTACCAGCGCGGCCGCGAACTGATCGGCAGCAAGGCCATCTCGAAAAGCGAATTCGACCGTCTCGCC
GCGCAGTGGGCCAAGACCAGCGCCACCGTCGCCGAGCTGAAGGCGGCGCTGGCGAAGAAGCGCGTGCTCGCG
CCCTTCGCCGGGACCATCGGCATCCGCCAGGTGGACGTCGGCGACTACGTCTCGCCCGGGACGCCGATCGCC
ACCTTGCAGGACCTTTCCACCCTGCTCCTGGATTTCCACCTGCCCGAGCAGGACTTCCCCCTGCTCAGCCGC
GGCCAGTTGGTGAAGGTCCGGGTCGCCGCCTACCCCGGCCAGGTGTTCGACGCCGAGATCGCCGCCATCAAC
CCCAAGGTCGACAACGAGACCCGCAACCTGCAGGTCCGCGCCGCCCTGGAGAACCCGGACGGCAAGCTGCTG
CCGGGCATGTTCGCCAACCTCGAGGTGATGTTGCCTGGCGAGGAACAACGCGTCGTGGTGCCGGAGACGGCG
ATCACCTTCACCCTCTACGGCGACTCGATCTACGTCGTCGGGCAGAAGAAGGACGAGCAGGGCCAGGTGTCG
AAGGATGACAAGGGCCAGCCGCAACGGGTCGTCGAGCGCCGCTTCGTCAGGATCGGCGAACGCCGCGAAGGC
CTGGCGGTGGTGCTCGAAGGCCTGGAGGGCGGCGAGCAGGTAGTGACTTCCGGGCAACTGAAGCTCGACAAC
GGCGCCGCGGTGGCCATCGTCGCCGAGCGGGACCTCCAGCAAGAGCACTGA
Translation:
MLLRRMLIMLAAVIAVVAILAGYKVYSIRQQIALFSAPKPPISVTASLAEKRPWQSRLPAIGSLKAFQGVTL
TAEVSGTVRDVLFLSGDQVKLDQPLIQLESDVEEATLRTAEADLGLARAEYQRGRELIGSKAISKSEFDRLA
AQWAKTSATVAELKAALAKKRVLAPFAGTIGIRQVDVGDYVSPGTPIATLQDLSTLLLDFHLPEQDFPLLSR
GQLVKVRVAAYPGQVFDAEIAAINPKVDNETRNLQVRAALENPDGKLLPGMFANLEVMLPGEEQRVVVPETA
ITFTLYGDSIYVVGQKKDEQGQVSKDDKGQPQRVVERRFVRIGERREGLAVVLEGLEGGEQVVTSGQLKLDN
GAAVAIVAERDLQQEH*
AnnotationID:1849GeneID:1840
AnnotatorUID: diggins
Modification Date/Time: 2005-05-02 07:07:13
Gene Name:
Confidence Code:3
GeneProduct:putative membrane fusion protein
Cell Localization:()
Synonyms:PA4374
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(15) Membrane proteins
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0845
Secondary Functional Category(ies):cell envelope biogenesis
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66532.1|AE016281_13 (AE016777) RND efflux membrane fusion protein-related protein
           [Pseudomonas putida KT2440]
          Length = 406

 Score =  437 bits (1124), Expect = e-122
 Identities = 224/375 (59%), Positives = 284/375 (75%)

>gb|AAO90607.1| (AE016963) efflux transporter, RND family, MFP subunit [Coxiella
           burnetii RSA 493]
          Length = 380

 Score =  254 bits (649), Expect = 6e-67
 Identities = 142/357 (39%), Positives = 214/357 (59%), Gaps = 10/357 (2%)

>gb|AAO09558.1|AE016800_163 (AE016800) Membrane-fusion protein [Vibrio vulnificus CMCP6]
          Length = 361

 Score =  248 bits (632), Expect = 6e-65
 Identities = 138/361 (38%), Positives = 217/361 (60%), Gaps = 16/361 (4%)







 
Structural Features:
COG0845, AcrA, Membrane-fusion protein 
[Cell envelope biogenesis, outer membrane]
CD-Length = 372 residues,  99.7% aligned
Score =  112 bits (281), Expect = 1e-25
Identities = 119/392 (30%), Positives = 176/392 (44%), Gaps = 42/392 (10%)






   
Genomic Context:






   
Comment:


















    ReferenceID:3683




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17132




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1840_cdd.html


    		




 
URL:

















    ReferenceID:20830




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1840
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3227
                           PA4374_tr
                           translation of PA4374
                           376
                           99.46
                           99.73
                           0
                           1839.0
     

     
     
100001
                           gb|AAG07762.1|AE004853_5
                           (AE004853) probable RND efflux membrane fusion protein precursor [Pseudomonas aeruginosa PAO1]
                           376
                           99.46
                           99.73
                           0
                           1839.0
     

     
     
100002
                           gb|AAN66532.1|AE016281_13
                           (AE016777) RND efflux membrane fusion protein-related protein [Pseudomonas putida KT2440]
                           406
                           55.17
                           69.95
                           30
                           1122.0
     

     
     
100003
                           gb|AAF93341.1|
                           (AE004106) conserved hypothetical protein [Vibrio cholerae O1 biovar eltor str. N16961]
                           384
                           38.54
                           57.29
                           24
                           666.0
     

     






      

          
GC ORFID: 44842How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4374Glimmer Score: 

          
Start: 4330694Stop: 4331824

          
Length: 1131


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4374 translation of PA4374Homolog Bit Score 712.0

          
Other Homologs:  t_PA4374 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTTGCTCCGCCGCATGTTGATCATGCTCGCCGCGGTGATCGCCGTGGTGGCGATTCTCGCCGGCTACAAG 
GTCTACTCCATCCGTCAGCAGATCGCCCTTTTCAGCGCACCGAAACCGCCGATCAGCGTGACCGCCAGCCTG 
GCCGAAAAGCGTCCCTGGCAGAGCCGCCTGCCAGCCATCGGCAGCCTCAAGGCATTCCAGGGCGTGACCCTC 
ACCGCCGAAGTCTCCGGCACGGTACGCGACGTACTGTTCCTTTCCGGCGACCAGGTGAAGCTGGACCAACCG 
CTGATCCAGCTGGAAAGCGACGTCGAGGAAGCCACCCTGCGCACTGCCGAGGCCGATCTCGGCCTGGCCAGG 
GCCGAGTACCAGCGCGGCCGCGAACTGATCGGCAGCAAGGCCATCTCGAAAAGCGAATTCGACCGTCTCGCC 
GCGCAGTGGGCCAAGACCAGCGCCACCGTCGCCGAGCTGAAGGCGGCGCTGGCGAAGAAGCGCGTGCTCGCG 
CCCTTCGCCGGGACCATCGGCATCCGCCAGGTGGACGTCGGCGACTACGTCTCGCCCGGGACGCCGATCGCC 
ACCTTGCAGGACCTTTCCACCCTGCTCCTGGATTTCCACCTGCCCGAGCAGGACTTCCCCCTGCTCAGCCGC 
GGCCAGTTGGTGAAGGTCCGGGTCGCCGCCTACCCCGGCCAGGTGTTCGACGCCGAGATCGCCGCCATCAAC 
CCCAAGGTCGACAACGAGACCCGCAACCTGCAGGTCCGCGCCGCCCTGGAGAACCCGGACGGCAAGCTGCTG 
CCGGGCATGTTCGCCAACCTCGAGGTGATGTTGCCTGGCGAGGAACAACGCGTCGTGGTGCCGGAGACGGCG 
ATCACCTTCACCCTCTACGGCGACTCGATCTACGTCGTCGGGCAGAAGAAGGACGAGCAGGGCCAGGTGTCG 
AAGGATGACAAGGGCCAGCCGCAACGGGTCGTCGAGCGCCGCTTCGTCAGGATCGGCGAACGCCGCGAAGGC 
CTGGCGGTGGTGCTCGAAGGCCTGGAGGGCGGCGAGCAGGTAGTGACTTCCGGGCAACTGAAGCTCGACAAC 
GGCGCCGCGGTGGCCATCGTCGCCGAGCGGGACCTCCAGCAAGAGCACTGA