ViewGene
Locus Name:
GeneID:
Location:

GeneID:1837
TrivialName: PA14_46230
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_46230
PAO1 Ortholog Locus:PA1409
Sequence Length:1041
Protein Length:346
Start: 4110979
Stop: 4109939
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04798.1|AE004570_6 (AE004570) acetylpolyamine aminohydrolase [Pseudomonas aeruginosa PAO1]
Identities = 344/346 (99%), Positives = 345/346 (99%)
Sequence:
ATGCTGAGCGTCTACAGCGACGATCATCGTCTGCACTTCGGCCAGTCGGAACTGGTCGACGGCAAGCTGCAA
CCCTGTTTCGAAATGCCCAGCCGGGCCGACACCGTGCTGGCCCGGGTGAAGTCGCAGAACCTTGGCGAGGTG
ATCGCGCCGAAGGATTTCGGCCGCGAGCCGCTGCTGCGCATCCACGACGCCGCCTACCTGGACTTCCTCCAG
GGCGCCTGGGCCCGCTGGACCGCCGAAGGCCACAGCGGCGACCTGGTGTCCACCACCTTCCCCGGCCGCCGC
CTGCGCCGCGACGGGCCGATCCCCACGGCGCTGATGGGCGAGCTGGGCTACTACAGCTTCGACACCGAGGCG
CCGATCACCGCCGGCACCTGGCAGGCCATCTACAGCTCCGCCCAGGTCGCGCTGACCGCCCAGGAGCATATG
CGCCAGGGCGCCCGCAGCGCCTTCGCTCTCTGCCGTCCGCCGGGCCATCACGCCGGTGGCGACTTCATGGGC
GGCTACTGCTTCCTCAACAATGCCGCCATCGCCACCCAGGCGTTCCTCGACCAGGGCGCCCGGCGCGTGGCG
ATCCTTGATGTCGACTATCACCATGGCAACGGCACGCAGGATATCTTCTACCGCCGCGACGACGTGCTGTTC
GCCTCGATCCATGGCGATCCGCGGGTCGAATACCCGTACTTCCTCGGCTACGCCGACGAGCGCGGCGAAGGC
GCCGGCGAGGGCTGCAACCACAACTATCCGCTGGCCCATAGCAGCGGCTGGGACCTCTGGTCGGCGGCGCTC
GACGACGCCTGCGTGCGGATCGCCGGCTACGCCCCGGATGCCCTGGTGATTTCCCTCGGCGTGGACACCTAC
AAGGAAGACCCGATCTCCCAGTTCAGGCTGGATTCGCCGGACTACCTGCGGATGGGCGAGCGCATCGCCCGG
CTGGGCCTGCCGACCCTGTTCATCATGGAAGGCGGCTATGCGGTGGAAGCCATCGGCATCAACGCGGTCAAC
GTGCTGCAGGGCTACGAAGGCGCGGCCCGCTGA
Translation:
MLSVYSDDHRLHFGQSELVDGKLQPCFEMPSRADTVLARVKSQNLGEVIAPKDFGREPLLRIHDAAYLDFLQ
GAWARWTAEGHSGDLVSTTFPGRRLRRDGPIPTALMGELGYYSFDTEAPITAGTWQAIYSSAQVALTAQEHM
RQGARSAFALCRPPGHHAGGDFMGGYCFLNNAAIATQAFLDQGARRVAILDVDYHHGNGTQDIFYRRDDVLF
ASIHGDPRVEYPYFLGYADERGEGAGEGCNHNYPLAHSSGWDLWSAALDDACVRIAGYAPDALVISLGVDTY
KEDPISQFRLDSPDYLRMGERIARLGLPTLFIMEGGYAVEAIGINAVNVLQGYEGAAR*
AnnotationID:1846GeneID:1837
AnnotatorUID: diggins
Modification Date/Time: 2005-05-27 07:07:41
Gene Name:aphA
Confidence Code:2
GeneProduct:acetylpolyamine aminohydrolase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(5) Carbon compound catabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam00850
Secondary Functional Category(ies):transcriptional regulator
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70905.1|AE016734_9 (AE016794) acetylpolyamine aminohydrolase [Pseudomonas putida
           KT2440]
          Length = 347

 Score =  523 bits (1346), Expect = e-148
 Identities = 250/344 (72%), Positives = 284/344 (82%), Gaps = 2/344 (0%)

>dbj|BAB49912.1| (AP003000) acetylpolyamine aminohydolase [Mesorhizobium loti]
          Length = 343

 Score =  423 bits (1087), Expect = e-118
 Identities = 204/342 (59%), Positives = 251/342 (73%), Gaps = 1/342 (0%)








 
Structural Features:
pfam00850, Hist_deacetyl, Histone deacetylase family. 
CD-Length = 316 residues,  90.2% aligned
Score =  190 bits (483), Expect = 3e-49
Identities = 85/290 (29%), Positives = 125/290 (43%), Gaps = 8/290 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:3677




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20824




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37427




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1837_cdd.html


    		




 
URL:

















    ReferenceID:37997




  
Author/Investigator(s):
        Okii M, Iyobe S, Mitsuhashi S.





  
Title:
        Mapping of the gene specifying aminoglycoside 3'-phosphotransferase II on the Pseudomonas aeruginosa chromosome.




  
PubMed:
        6307974


MedLine:
        




    
Source:
J Bacteriol. 1983 Aug;155(2):643-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6307974

















    ReferenceID:37998




  
Author/Investigator(s):
        Trieu-Cuot P, Klier A, Courvalin P.





  
Title:
        DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and Bacillus subtilis.




  
PubMed:
        3920478


MedLine:
        




    
Source:
Mol Gen Genet. 1985;198(2):348-52.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3920478

















    ReferenceID:37999




  
Author/Investigator(s):
        Sakurada K, Ohta T, Fujishiro K, Hasegawa M, Aisaka K.





  
Title:
        Acetylpolyamine amidohydrolase from Mycoplana ramosa: gene cloning and characterization of the metal-substituted enzyme.




  
PubMed:
        8824626


MedLine:
        




    
Source:
J Bacteriol. 1996 Oct;178(19):5781-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8824626









           
Homologs By Global Alignment 

           

       



     
Gene ID:1837
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3221
                           PA1409_tr
                           translation of PA1409
                           346
                           99.42
                           99.71
                           0
                           1841.0
     

     
     
99847
                           gb|AAG04798.1|AE004570_6
                           (AE004570) acetylpolyamine aminohydrolase [Pseudomonas aeruginosa PAO1]
                           346
                           99.42
                           99.71
                           0
                           1841.0
     

     
     
99848
                           gb|AAN70905.1|AE016734_9
                           (AE016794) acetylpolyamine aminohydrolase [Pseudomonas putida KT2440]
                           349
                           72.20
                           81.94
                           5
                           1346.0
     

     
     
3222
                           PA0321_tr
                           translation of PA0321
                           346
                           68.78
                           77.16
                           2
                           1262.0
     

     
     
99849
                           gb|AAG03710.1|AE004470_4
                           (AE004470) probable acetylpolyamine aminohydrolase [Pseudomonas aeruginosa PAO1]
                           346
                           68.78
                           77.16
                           2
                           1262.0
     

     






      

          
GC ORFID: 44839How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1409Glimmer Score: 

          
Start: 842930Stop: 843970

          
Length: 1041


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1409 translation of PA1409Homolog Bit Score 713.0

          
Other Homologs:  t_PA0321 (ORF: BLASTX 489.0), t_PA1409 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCTGAGCGTCTACAGCGACGATCATCGTCTGCACTTCGGCCAGTCGGAACTGGTCGACGGCAAGCTGCAA 
CCCTGTTTCGAAATGCCCAGCCGGGCCGACACCGTGCTGGCCCGGGTGAAGTCGCAGAACCTTGGCGAGGTG 
ATCGCGCCGAAGGATTTCGGCCGCGAGCCGCTGCTGCGCATCCACGACGCCGCCTACCTGGACTTCCTCCAG 
GGCGCCTGGGCCCGCTGGACCGCCGAAGGCCACAGCGGCGACCTGGTGTCCACCACCTTCCCCGGCCGCCGC 
CTGCGCCGCGACGGGCCGATCCCCACGGCGCTGATGGGCGAGCTGGGCTACTACAGCTTCGACACCGAGGCG 
CCGATCACCGCCGGCACCTGGCAGGCCATCTACAGCTCCGCCCAGGTCGCGCTGACCGCCCAGGAGCATATG 
CGCCAGGGCGCCCGCAGCGCCTTCGCTCTCTGCCGTCCGCCGGGCCATCACGCCGGTGGCGACTTCATGGGC 
GGCTACTGCTTCCTCAACAATGCCGCCATCGCCACCCAGGCGTTCCTCGACCAGGGCGCCCGGCGCGTGGCG 
ATCCTTGATGTCGACTATCACCATGGCAACGGCACGCAGGATATCTTCTACCGCCGCGACGACGTGCTGTTC 
GCCTCGATCCATGGCGATCCGCGGGTCGAATACCCGTACTTCCTCGGCTACGCCGACGAGCGCGGCGAAGGC 
GCCGGCGAGGGCTGCAACCACAACTATCCGCTGGCCCATAGCAGCGGCTGGGACCTCTGGTCGGCGGCGCTC 
GACGACGCCTGCGTGCGGATCGCCGGCTACGCCCCGGATGCCCTGGTGATTTCCCTCGGCGTGGACACCTAC 
AAGGAAGACCCGATCTCCCAGTTCAGGCTGGATTCGCCGGACTACCTGCGGATGGGCGAGCGCATCGCCCGG 
CTGGGCCTGCCGACCCTGTTCATCATGGAAGGCGGCTATGCGGTGGAAGCCATCGGCATCAACGCGGTCAAC 
GTGCTGCAGGGCTACGAAGGCGCGGCCCGCTGA