ViewGene
Locus Name:
GeneID:
Location:

GeneID:1797
TrivialName: PA14_23270
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23270
PAO1 Ortholog Locus:PA3167
Sequence Length:1086
Protein Length:361
Start: 2017607
Stop: 2018692
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06555.1|AE004740_8 (AE004740) 3-phosphoserine aminotransferase [Pseudomonas aeruginosa PAO1]
Identities = 360/361 (99%), Positives = 360/361 (99%)
Sequence:
GTGAGCAAGCGAGCCTTCAATTTCTGCGCCGGTCCCGCGGCGCTTCCCGACGCAGTTCTGCAACGTGCCCAG
GCCGAGCTTCTCGACTGGCGGGGCAAGGGCCTTTCGGTCATGGAAATGAGCCACCGTAGCGACGACTACGTG
GCCATCGCCAGCAAGGCCGAGCAGGACCTGCGCGACCTGCTCGACATTCCCTCGGACTACAAGGTGCTGTTC
CTGCAGGGCGGCGCCAGCCAGCAGTTCGCCGAGATTCCGCTGAACCTGCTGCCCGAAGATGGCGTCGCCGAC
TATATCGATACCGGTATCTGGTCGAAGAAGGCCATCGAGGAGGCTCGTCGCTATGGCACCGTGAATGTCGCG
GCCAGCGCCAAGGAGTACGACTACTTCGCCATTCCGGGTCAGAACGAGTGGACGCTGACCAAGGACGCGGCC
TATGTGCACTACGCCTCCAACGAGACCATCGGCGGCCTCGAGTTCGACTGGATTCCCGAGACCGGCGACGTG
CCGCTGGTCACCGACATGTCCTCCGATATCCTCTCGCGCCCGCTCGACGTGTCCCGCTTCGGCCTGATCTAT
GCCGGGGCGCAGAAGAACATCGGCCCGTCCGGCCTGGTGGTGGTGATCGTTCGCGAAGACCTGCTCGGCCGC
GCCCGCAGCGTCTGCCCGACCATGCTCAACTACAAGATCGCCGCGGACAACGGTTCCATGTACAACACCCCG
GCGACCTACTCCTGGTACCTGTCCGGCTTGGTCTTCGAATGGCTGAAGGAGCAGGGCGGGGTGACCGCGATG
GAGCAGCGCAACCGCGCCAAGAAGGACCTGCTGTACAAGACCATCGATGCCAGCGACTTCTACACCAACCCG
ATCCAGCCGAGCGCCCGCTCCTGGATGAACGTGCCGTTCCGCCTGGCCGACGAGCGTCTCGACAAGCCGTTC
CTGGAAGGCGCCGAGGCGCGCGGGCTGCTCAACCTGAAAGGCCACCGCTCGGTCGGCGGCATGCGCGCTTCC
ATCTACAACGCCCTTGGCCTGGACGCGGTCGAGGCGCTGGTCGCATACATGGCGGAGTTCGAGAAGGAGCAC
GGCTGA
Translation:
MSKRAFNFCAGPAALPDAVLQRAQAELLDWRGKGLSVMEMSHRSDDYVAIASKAEQDLRDLLDIPSDYKVLF
LQGGASQQFAEIPLNLLPEDGVADYIDTGIWSKKAIEEARRYGTVNVAASAKEYDYFAIPGQNEWTLTKDAA
YVHYASNETIGGLEFDWIPETGDVPLVTDMSSDILSRPLDVSRFGLIYAGAQKNIGPSGLVVVIVREDLLGR
ARSVCPTMLNYKIAADNGSMYNTPATYSWYLSGLVFEWLKEQGGVTAMEQRNRAKKDLLYKTIDASDFYTNP
IQPSARSWMNVPFRLADERLDKPFLEGAEARGLLNLKGHRSVGGMRASIYNALGLDAVEALVAYMAEFEKEH
G*
AnnotationID:1806GeneID:1797
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 12:12:35
Gene Name:serC
Confidence Code:2
GeneProduct:3-phosphoserine aminotransferase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam00266,COG1932
Secondary Functional Category(ies):biosynthesis of cofactors, prosthetic groups and carriers
EC Number:2.6.1.52
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67388.1|AE016365_3 (AE016780) 3-phosphoserine aminotransferase [Pseudomonas putida
           KT2440]
          Length = 361

 Score =  656 bits (1692), Expect = 0.0
 Identities = 321/361 (88%), Positives = 341/361 (94%)

>gb|AAO55266.1| (AE016862) phosphoserine aminotransferase [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 361

 Score =  609 bits (1571), Expect = e-174
 Identities = 296/361 (81%), Positives = 330/361 (91%)

>emb|CAC90218.1| (AJ414148) phosphoserine aminotransferase [Yersinia pestis CO92]
          Length = 361

 Score =  416 bits (1070), Expect = e-116
 Identities = 204/359 (56%), Positives = 268/359 (74%), Gaps = 1/359 (0%)








 
Structural Features:
pfam00266, Aminotran_5, Aminotransferase class-V.
CD-Length = 354 residues, 100.0% aligned
Score =  213 bits (544), Expect = 3e-56
Identities = 99/357 (27%), Positives = 138/357 (38%), Gaps = 25/357 (7%)

COG1932, SerC, Phosphoserine aminotransferase 
[Coenzyme metabolism / Amino acid transport and metabolism]
CD-Length = 365 residues,  98.9% aligned
Score =  497 bits (1282), Expect = 7e-142
Identities = 208/362 (57%), Positives = 263/362 (72%), Gaps = 5/362 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14431




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20744




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32375




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1797_cdd.html


    		




 
URL:

















    ReferenceID:33944




  
Author/Investigator(s):
        Xie G, Brettin TS, Bonner CA, Jensen RA.





  
Title:
        Mixed-function supraoperons that exhibit overall conservation, albeit shuffled gene organization, across wide intergenomic distances within eubacteria.




  
PubMed:
        10518299


MedLine:
        




    
Source:
Microb Comp Genomics. 1999;4(1):5-28.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10518299

















    ReferenceID:33945




  
Author/Investigator(s):
        Xie G, Bonner CA, Jensen RA.





  
Title:
        A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling.




  
PubMed:
        10368439


MedLine:
        




    
Source:
J Mol Evol. 1999 Jul;49(1):108-21.
Erratum in:
    * J Mol Evol 2000 Feb;50(2):202.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10368439

















    ReferenceID:33946




  
Author/Investigator(s):
        Metcalf WW, Zhang JK, Shi X, Wolfe RS.





  
Title:
        Molecular, genetic, and biochemical characterization of the serC gene of Methanosarcina barkeri Fusaro.




  
PubMed:
        8824630


MedLine:
        




    
Source:
J Bacteriol. 1996 Oct;178(19):5797-802.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8824630

















    ReferenceID:33947




  
Author/Investigator(s):
        Griffin HG, Griffin AM.





  
Title:
        Cloning and DNA sequence analysis of the serC-aroA operon from Salmonella gallinarum; evolutionary relationships between the prokaryotic and eukaryotic aroA-encoded enzymes.




  
PubMed:
        2045774


MedLine:
        




    
Source:
J Gen Microbiol. 1991 Jan;137 ( Pt 1):113-21.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2045774

















    ReferenceID:33948




  
Author/Investigator(s):
        Griffin HG.





  
Title:
        Nucleotide sequence of the Salmonella serC gene.




  
PubMed:
        2198540


MedLine:
        




    
Source:
Nucleic Acids Res. 1990 Jul 25;18(14):4260.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2198540

















    ReferenceID:33949




  
Author/Investigator(s):
        O'Gaora P, Maskel D, Coleman D, Cafferkey M, Dougan G.





  
Title:
        Cloning and characterisation of the serC and aroA genes of Yersinia enterocolitica, and construction of an aroA mutant.




  
PubMed:
        2691337


MedLine:
        




    
Source:
Gene. 1989 Dec 7;84(1):23-30.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2691337

















    ReferenceID:33950




  
Author/Investigator(s):
        Duncan K, Coggins JR.





  
Title:
        The serC-aro A operon of Escherichia coli. A mixed function operon encoding enzymes from two different amino acid biosynthetic pathways.




  
PubMed:
        3518706


MedLine:
        




    
Source:
Biochem J. 1986 Feb 15;234(1):49-57.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3518706

















    ReferenceID:33951




  
Author/Investigator(s):
        Hoiseth SK, Stocker BA.





  
Title:
        Genes aroA and serC of Salmonella typhimurium constitute an operon.




  
PubMed:
        2989248


MedLine:
        




    
Source:
J Bacteriol. 1985 Jul;163(1):355-61.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2989248









           
Homologs By Global Alignment 

           

       



     
Gene ID:1797
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3166
                           PA3167_tr
                           translation of PA3167
                           361
                           99.72
                           99.72
                           0
                           1866.0
     

     
     
98310
                           gb|AAG06555.1|AE004740_8
                           (AE004740) 3-phosphoserine aminotransferase [Pseudomonas aeruginosa PAO1]
                           361
                           99.44
                           99.72
                           0
                           1863.0
     

     
     
98311
                           gb|AAN67388.1|AE016365_3
                           (AE016780) 3-phosphoserine aminotransferase [Pseudomonas putida KT2440]
                           361
                           88.64
                           94.45
                           0
                           1688.0
     

     
     
98312
                           gb|AAD47359.1|AF038578_2
                           (AF038578) 3-phosphoserine aminotransferase [Pseudomonas stutzeri]
                           366
                           85.51
                           92.62
                           5
                           1649.0
     

     
     
98313
                           gb|AAO55266.1|
                           (AE016862) phosphoserine aminotransferase [Pseudomonas syringae pv. tomato str. DC3000]
                           361
                           81.71
                           91.41
                           0
                           1567.0
     

     






      

          
GC ORFID: 44799How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3167Glimmer Score: 

          
Start: 2936324Stop: 2935239

          
Length: 1086


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3167 translation of PA3167Homolog Bit Score 723.0

          
Other Homologs:  t_PA3167 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGAGCAAGCGAGCCTTCAATTTCTGCGCCGGTCCCGCGGCGCTTCCCGACGCAGTTCTGCAACGTGCCCAG 
GCCGAGCTTCTCGACTGGCGGGGCAAGGGCCTTTCGGTCATGGAAATGAGCCACCGTAGCGACGACTACGTG 
GCCATCGCCAGCAAGGCCGAGCAGGACCTGCGCGACCTGCTCGACATTCCCTCGGACTACAAGGTGCTGTTC 
CTGCAGGGCGGCGCCAGCCAGCAGTTCGCCGAGATTCCGCTGAACCTGCTGCCCGAAGATGGCGTCGCCGAC 
TATATCGATACCGGTATCTGGTCGAAGAAGGCCATCGAGGAGGCTCGTCGCTATGGCACCGTGAATGTCGCG 
GCCAGCGCCAAGGAGTACGACTACTTCGCCATTCCGGGTCAGAACGAGTGGACGCTGACCAAGGACGCGGCC 
TATGTGCACTACGCCTCCAACGAGACCATCGGCGGCCTCGAGTTCGACTGGATTCCCGAGACCGGCGACGTG 
CCGCTGGTCACCGACATGTCCTCCGATATCCTCTCGCGCCCGCTCGACGTGTCCCGCTTCGGCCTGATCTAT 
GCCGGGGCGCAGAAGAACATCGGCCCGTCCGGCCTGGTGGTGGTGATCGTTCGCGAAGACCTGCTCGGCCGC 
GCCCGCAGCGTCTGCCCGACCATGCTCAACTACAAGATCGCCGCGGACAACGGTTCCATGTACAACACCCCG 
GCGACCTACTCCTGGTACCTGTCCGGCTTGGTCTTCGAATGGCTGAAGGAGCAGGGCGGGGTGACCGCGATG 
GAGCAGCGCAACCGCGCCAAGAAGGACCTGCTGTACAAGACCATCGATGCCAGCGACTTCTACACCAACCCG 
ATCCAGCCGAGCGCCCGCTCCTGGATGAACGTGCCGTTCCGCCTGGCCGACGAGCGTCTCGACAAGCCGTTC 
CTGGAAGGCGCCGAGGCGCGCGGGCTGCTCAACCTGAAAGGCCACCGCTCGGTCGGCGGCATGCGCGCTTCC 
ATCTACAACGCCCTTGGCCTGGACGCGGTCGAGGCGCTGGTCGCATACATGGCGGAGTTCGAGAAGGAGCAC 
GGCTGA