ViewGene
Locus Name:
GeneID:
Location:

GeneID:1785
TrivialName: PA14_23290
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23290
PAO1 Ortholog Locus:PA3165
Sequence Length:1110
Protein Length:369
Start: 2019858
Stop: 2020967
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06553.1|AE004740_6 (AE004740) histidinol-phosphate aminotransferase [Pseudomonas aeruginosa PAO1]
Identities = 369/369 (100%), Positives = 369/369 (100%)
Sequence:
ATGTCCGATTTCCTTGCCCTGGCCCAGCCGGGGGTGCAAAAGCTGTCGCCCTACGTCCCTGGCAAGCCGGTG
GACGAACTGGCCCGCGAGCTGGGCATCGACCCTGCGGCGATCGTCAAGCTCGCCAGCAACGAGAACCCGCTG
GGTGCGAGCCCAAAGGCGCTGGAGGCTATCCGCGCCGAACTGGCGGAACTGACCCGTTATCCTGACGGCAAC
GGTTTCGAACTCAAGCGCAAGCTGGCCGAGCGTTGCGCGGTGGATGCGGCGCAGGTGACCCTGGGCAACGGC
TCCAACGACATTCTCGACCTGGTCGCCCGTGCCTACCTCGCGCCTGGTCTGAACGCCGTGTTCAGCGAACAT
GCCTTCGCCGTCTACCCGATCGCCACCCAGGCCGTGGGCGCCGAGGGGCGGGCGGTCAAGGCGCGCGCCTGG
GGGCATGACCTGGAAGCGATGCTCGCCGCCATCGATGGGCAAACTCGCGTGGTGTTCGTCGCCAACCCGAAC
AACCCGACCGGGACCTGGTTCGGTGCGGACGCCCTGGAGCGGTTCCTCGCCCAGGTGCCGGCGGAGGTGCTG
GTGGTGCTGGACGAGGCCTATATCGAATACGCCGAGGGCGACGAGCTGCCCGATGGCCTGGACTACCTGGCG
CGGCACCCCAACCTGCTGGTCTCGCGGACCTTCTCCAAGGCCTATGGCCTGGCTTCGCTGCGGGTCGGCTAC
GCGCTTTCGAGCAAGGCGGTGGCCGATGTGCTCAACCGCGTGCGCCAGCCGTTCAATGTCAATAGCCTGGCC
CTGGCGGCTGCCTGCGCGGCGCTGGATGACCATGACTACCTGGCGCAGAGTCGCCGCCTAAACGATTCCGGC
ATGGCGCAGCTGGAGGATGGCTTCCACGCGTTGGGCCTGTCCTGGATTCCCTCGAAGGGCAACTTCATCGCC
GTGGATCTGGCTCGCGATGCCGGTCCGGTCTACCAGGCGCTGCTGCGCGAAGGTGTGATCGTGCGTCCGGTG
GCTGGCTACGGGATGCCGACCTTCCTGCGCGTCTCCATCGGGCTGCCGGAAGAGAACGATCGTTTCCTCCAG
GCGCTGGGCAAGGTGCTGGCGCATGACTGA
Translation:
MSDFLALAQPGVQKLSPYVPGKPVDELARELGIDPAAIVKLASNENPLGASPKALEAIRAELAELTRYPDGN
GFELKRKLAERCAVDAAQVTLGNGSNDILDLVARAYLAPGLNAVFSEHAFAVYPIATQAVGAEGRAVKARAW
GHDLEAMLAAIDGQTRVVFVANPNNPTGTWFGADALERFLAQVPAEVLVVLDEAYIEYAEGDELPDGLDYLA
RHPNLLVSRTFSKAYGLASLRVGYALSSKAVADVLNRVRQPFNVNSLALAAACAALDDHDYLAQSRRLNDSG
MAQLEDGFHALGLSWIPSKGNFIAVDLARDAGPVYQALLREGVIVRPVAGYGMPTFLRVSIGLPEENDRFLQ
ALGKVLAHD*
AnnotationID:1794GeneID:1785
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 12:12:43
Gene Name:hisC2
Confidence Code:2
GeneProduct: histidinol-phosphate aminotransferase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:imidazole acetol phosphate aminotransferase
Functional Category Confidence Code:5
COGs:COG0079
Secondary Functional Category(ies):
EC Number:2.6.1.9
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAD47361.1|AF038578_4 (AF038578) imidazole acetol phosphate aminotransferase [Pseudomonas
           stutzeri]
          Length = 366

 Score =  454 bits (1167), Expect = e-127
 Identities = 243/369 (65%), Positives = 277/369 (75%), Gaps = 11/369 (2%)

>gb|AAB58526.1| (U83322) imidazoleacetol phosphate aminotransferase
           [Methylobacillus flagellatus]
          Length = 368

 Score =  397 bits (1019), Expect = e-110
 Identities = 205/366 (56%), Positives = 264/366 (72%), Gaps = 2/366 (0%)

>gb|AAC22821.1| (U32796) histidinol-phosphate aminotransferase (hisH) [Haemophilus
           influenzae Rd]
          Length = 366

 Score =  386 bits (992), Expect = e-106
 Identities = 191/363 (52%), Positives = 257/363 (70%), Gaps = 2/363 (0%)








 
Structural Features:
COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase 
and cobyric acid decarboxylase 
[Amino acid transport and metabolism]
CD-Length = 356 residues,  99.2% aligned
Score =  335 bits (860), Expect = 5e-93
Identities = 167/365 (45%), Positives = 230/365 (63%), Gaps = 16/365 (4%)






   
Genomic Context:






   
Comment:


















    ReferenceID:3573




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20720




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32377




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1785_cdd.html


    		




 
URL:

















    ReferenceID:33928




  
Author/Investigator(s):
        Grisolia V, Carlomagno MS, Nappo AG, Bruni CB.





  
Title:
        Cloning, structure, and expression of the Escherichia coli K-12 hisC gene.




  
PubMed:
        2999081


MedLine:
        




    
Source:
J Bacteriol. 1985 Dec;164(3):1317-23.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2999081

















    ReferenceID:33929




  
Author/Investigator(s):
        Riggs D, Artz S.





  
Title:
        The hisD-hisC gene border of the Salmonella typhimurium histidine operon.




  
PubMed:
        6390096


MedLine:
        




    
Source:
Mol Gen Genet. 1984;196(3):526-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6390096









           
Homologs By Global Alignment 

           

       



     
Gene ID:1785
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3149
                           PA3165_tr
                           translation of PA3165
                           369
                           99.99
                           99.99
                           0
                           1871.0
     

     
     
97854
                           gb|AAG06553.1|AE004740_6
                           (AE004740) histidinol-phosphate aminotransferase [Pseudomonas aeruginosa PAO1]
                           369
                           99.99
                           99.99
                           0
                           1871.0
     

     
     
97855
                           gb|AAD47361.1|AF038578_4
                           (AF038578) imidazole acetol phosphate aminotransferase [Pseudomonas stutzeri]
                           374
                           64.97
                           74.06
                           13
                           1175.0
     

     
     
97856
                           gb|AAB58526.1|
                           (U83322) imidazoleacetol phosphate aminotransferase [Methylobacillus flagellatus]
                           370
                           55.40
                           71.35
                           3
                           1018.0
     

     
     
97858
                           emb|CAD14607.1|
                           (AL646061) PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE PROTEIN [Ralstonia solanacearum]
                           376
                           54.52
                           68.61
                           9
                           987.0
     

     






      

          
GC ORFID: 44787How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3165Glimmer Score: 

          
Start: 2934073Stop: 2932964

          
Length: 1110


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3165 translation of PA3165Homolog Bit Score 725.0

          
Other Homologs:  t_PA3165 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCGATTTCCTTGCCCTGGCCCAGCCGGGGGTGCAAAAGCTGTCGCCCTACGTCCCTGGCAAGCCGGTG 
GACGAACTGGCCCGCGAGCTGGGCATCGACCCTGCGGCGATCGTCAAGCTCGCCAGCAACGAGAACCCGCTG 
GGTGCGAGCCCAAAGGCGCTGGAGGCTATCCGCGCCGAACTGGCGGAACTGACCCGTTATCCTGACGGCAAC 
GGTTTCGAACTCAAGCGCAAGCTGGCCGAGCGTTGCGCGGTGGATGCGGCGCAGGTGACCCTGGGCAACGGC 
TCCAACGACATTCTCGACCTGGTCGCCCGTGCCTACCTCGCGCCTGGTCTGAACGCCGTGTTCAGCGAACAT 
GCCTTCGCCGTCTACCCGATCGCCACCCAGGCCGTGGGCGCCGAGGGGCGGGCGGTCAAGGCGCGCGCCTGG 
GGGCATGACCTGGAAGCGATGCTCGCCGCCATCGATGGGCAAACTCGCGTGGTGTTCGTCGCCAACCCGAAC 
AACCCGACCGGGACCTGGTTCGGTGCGGACGCCCTGGAGCGGTTCCTCGCCCAGGTGCCGGCGGAGGTGCTG 
GTGGTGCTGGACGAGGCCTATATCGAATACGCCGAGGGCGACGAGCTGCCCGATGGCCTGGACTACCTGGCG 
CGGCACCCCAACCTGCTGGTCTCGCGGACCTTCTCCAAGGCCTATGGCCTGGCTTCGCTGCGGGTCGGCTAC 
GCGCTTTCGAGCAAGGCGGTGGCCGATGTGCTCAACCGCGTGCGCCAGCCGTTCAATGTCAATAGCCTGGCC 
CTGGCGGCTGCCTGCGCGGCGCTGGATGACCATGACTACCTGGCGCAGAGTCGCCGCCTAAACGATTCCGGC 
ATGGCGCAGCTGGAGGATGGCTTCCACGCGTTGGGCCTGTCCTGGATTCCCTCGAAGGGCAACTTCATCGCC 
GTGGATCTGGCTCGCGATGCCGGTCCGGTCTACCAGGCGCTGCTGCGCGAAGGTGTGATCGTGCGTCCGGTG 
GCTGGCTACGGGATGCCGACCTTCCTGCGCGTCTCCATCGGGCTGCCGGAAGAGAACGATCGTTTCCTCCAG 
GCGCTGGGCAAGGTGCTGGCGCATGACTGA