ViewGene
Locus Name:
GeneID:
Location:

GeneID:1736
TrivialName: PA14_48280
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_48280
PAO1 Ortholog Locus:PA1237
Sequence Length:1152
Protein Length:383
Start: 4295514
Stop: 4296665
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04626.1|AE004553_3 (AE004553) probable multidrug resistance efflux pump [Pseudomonas aeruginosa PAO1]
Identities = 378/383 (98%), Positives = 379/383 (98%)
Sequence:
ATGAACCAGGCAATCAGGGAACCCATCGAACACACCACTGGCGAAACCATGCCAGCAGTCACGCGCCGGCGC
CGAACCTGGCTGCTGGGCGGCCTCGCCGGCGCCATCGCGCTCGCCGCCCTGCTGGCCTGGTGGTGGAGCAGC
GGACGCTTCCTGGAGGGCACCGACGATGCCTATGTACGCGCCGACTGGGTGGCGGTCAGCGCGCAGGTCTCC
GGCTACGTCGCCGAGGTGCTGGTGGCCGACGACGCCGACGTCCAGGCCGGCGACCTGCTGCTGCGCCTGGAC
CCGCGCGACTTCCGCCAGCGCCTGCGCGCCGCCGAGGCCCGCGAAGCGGCGGCGCAGGCGGCGCTGGAAGCC
CAGCGCGCGAAGCTGGAGACCCTCGATCGGCAACTGCTGGAGCAGGTGCAGACGATCAGCCGCGCCCGCGCC
GATGGCGAAGCGGCGCGAGCCGAATGGCGCCGCGCCGAGACCGACTGGCGACGCTACCGGCAATTGGCCGAC
GAGCATGCCACCAGTCGCCAGCGCCTGGAGAATGCCGACGCGGCGCACCAGCGAGCGCGGGCGGCGGCGCGG
CGGGCAAGCGCCGAGGAAGGCCGCCAGCGCGCCGCCAGGGACGTACTGAAGAGCCGGCGACGCGAGGCGGAG
GCGGCGCTCGCCCAGCGCCAGGCGGAGCTGCAGGAAGCCGCGGCGGCGCGCGAACTGGCGCGCCACGCCCTG
GACGATACCGAAATCCGCGCCCCATTCGCCGGCCGCGTCGGCCAGCGCAAGGTGCGCCTGCGCCAGTACGTC
ACGCCGGGGCTGCCGCTGCTGGCGGTGGTGCCGCTGGAGCAGGCCTACGTGGTGGCCAACTACAAGGAGACC
CAGCTCGAACACATCCGCCCCGGGCAACCGGTAGAGCTGGAGGTGGACACGTTCGGCCGCCGCTGGCGCGGC
CGCGTCGACAGCGTGGCGCCGGCCTCCGGCGCGGTATTCGCGCTGCTGCCGCCGGACAACGCCACCGGCAAC
TTCACCAAGATCGTCCAGCGCTTCCCGGTGCGTATCCGCCTGGACACCGACGCCGCCGAGCGGGGCCGGCTG
CTGCCGGGGATGTCGGTGATCGCCACCGTGGACACTCGCGAACCGGACGGAGCCTCCGCCGATGAGCGCTGA
Translation:
MNQAIREPIEHTTGETMPAVTRRRRTWLLGGLAGAIALAALLAWWWSSGRFLEGTDDAYVRADWVAVSAQVS
GYVAEVLVADDADVQAGDLLLRLDPRDFRQRLRAAEAREAAAQAALEAQRAKLETLDRQLLEQVQTISRARA
DGEAARAEWRRAETDWRRYRQLADEHATSRQRLENADAAHQRARAAARRASAEEGRQRAARDVLKSRRREAE
AALAQRQAELQEAAAARELARHALDDTEIRAPFAGRVGQRKVRLRQYVTPGLPLLAVVPLEQAYVVANYKET
QLEHIRPGQPVELEVDTFGRRWRGRVDSVAPASGAVFALLPPDNATGNFTKIVQRFPVRIRLDTDAAERGRL
LPGMSVIATVDTREPDGASADER*
AnnotationID:1745GeneID:1736
AnnotatorUID: diggins
Modification Date/Time: 2005-02-22 08:08:22
Gene Name:
Confidence Code:3
GeneProduct:putative multidrug resistance efflux pump
Cell Localization:()
Synonyms:PA1237
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(3) Antibiotic resistance and susceptibility
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1566
Secondary Functional Category(ies):transport of small molecules
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67682.1|AE016398_6 (AE016781) multidrug efflux MFS membrane fusion protein, putative
           [Pseudomonas putida KT2440]
          Length = 425

 Score =  352 bits (902), Expect = 3e-96
 Identities = 204/381 (53%), Positives = 255/381 (66%), Gaps = 2/381 (0%)

>dbj|BAC52858.1| (AP005962) multidrug resistance efflux pump [Bradyrhizobium
           japonicum USDA 110]
          Length = 393

 Score =  267 bits (683), Expect = 7e-71
 Identities = 166/352 (47%), Positives = 217/352 (61%), Gaps = 16/352 (4%)








 
Structural Features:
COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms]
CD-Length = 352 residues,  96.3% aligned
Score =  281 bits (720), Expect = 1e-76
Identities = 148/363 (40%), Positives = 201/363 (55%), Gaps = 27/363 (7%)







   
Genomic Context:






   
Comment:


















    ReferenceID:3475




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20622




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37547




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1736_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1736
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3048
                           PA1237_tr
                           translation of PA1237
                           383
                           98.69
                           98.95
                           0
                           1898.0
     

     
     
94161
                           gb|AAG04626.1|AE004553_3
                           (AE004553) probable multidrug resistance efflux pump [Pseudomonas aeruginosa PAO1]
                           383
                           98.69
                           98.95
                           0
                           1898.0
     

     
     
94162
                           gb|AAN67682.1|AE016398_6
                           (AE016781) multidrug efflux MFS membrane fusion protein, putative [Pseudomonas putida KT2440]
                           428
                           47.66
                           59.57
                           48
                           905.0
     

     
     
3049
                           PA2836_tr
                           translation of PA2836
                           388
                           43.04
                           56.70
                           39
                           673.0
     

     
     
94164
                           gb|AAG06224.1|AE004710_6
                           (AE004710) probable secretion protein [Pseudomonas aeruginosa PAO1]
                           388
                           43.04
                           56.70
                           39
                           673.0
     

     






      

          
GC ORFID: 44738How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1237Glimmer Score: 

          
Start: 658394Stop: 657243

          
Length: 1152


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1237 translation of PA1237Homolog Bit Score 735.0

          
Other Homologs:  t_PA2836 (ORF: BLASTX 259.0), t_PA3136 (ORF: BLASTX 224.0), t_PA1237 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACCAGGCAATCAGGGAACCCATCGAACACACCACTGGCGAAACCATGCCAGCAGTCACGCGCCGGCGC 
CGAACCTGGCTGCTGGGCGGCCTCGCCGGCGCCATCGCGCTCGCCGCCCTGCTGGCCTGGTGGTGGAGCAGC 
GGACGCTTCCTGGAGGGCACCGACGATGCCTATGTACGCGCCGACTGGGTGGCGGTCAGCGCGCAGGTCTCC 
GGCTACGTCGCCGAGGTGCTGGTGGCCGACGACGCCGACGTCCAGGCCGGCGACCTGCTGCTGCGCCTGGAC 
CCGCGCGACTTCCGCCAGCGCCTGCGCGCCGCCGAGGCCCGCGAAGCGGCGGCGCAGGCGGCGCTGGAAGCC 
CAGCGCGCGAAGCTGGAGACCCTCGATCGGCAACTGCTGGAGCAGGTGCAGACGATCAGCCGCGCCCGCGCC 
GATGGCGAAGCGGCGCGAGCCGAATGGCGCCGCGCCGAGACCGACTGGCGACGCTACCGGCAATTGGCCGAC 
GAGCATGCCACCAGTCGCCAGCGCCTGGAGAATGCCGACGCGGCGCACCAGCGAGCGCGGGCGGCGGCGCGG 
CGGGCAAGCGCCGAGGAAGGCCGCCAGCGCGCCGCCAGGGACGTACTGAAGAGCCGGCGACGCGAGGCGGAG 
GCGGCGCTCGCCCAGCGCCAGGCGGAGCTGCAGGAAGCCGCGGCGGCGCGCGAACTGGCGCGCCACGCCCTG 
GACGATACCGAAATCCGCGCCCCATTCGCCGGCCGCGTCGGCCAGCGCAAGGTGCGCCTGCGCCAGTACGTC 
ACGCCGGGGCTGCCGCTGCTGGCGGTGGTGCCGCTGGAGCAGGCCTACGTGGTGGCCAACTACAAGGAGACC 
CAGCTCGAACACATCCGCCCCGGGCAACCGGTAGAGCTGGAGGTGGACACGTTCGGCCGCCGCTGGCGCGGC 
CGCGTCGACAGCGTGGCGCCGGCCTCCGGCGCGGTATTCGCGCTGCTGCCGCCGGACAACGCCACCGGCAAC 
TTCACCAAGATCGTCCAGCGCTTCCCGGTGCGTATCCGCCTGGACACCGACGCCGCCGAGCGGGGCCGGCTG 
CTGCCGGGGATGTCGGTGATCGCCACCGTGGACACTCGCGAACCGGACGGAGCCTCCGCCGATGAGCGCTGA