ViewGene
Locus Name:
GeneID:
Location:

GeneID:1669
TrivialName: PA14_46470
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_46470
PAO1 Ortholog Locus:PA1375
Sequence Length:1143
Protein Length:380
Start: 4136281
Stop: 4135139
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04764.1|AE004567_3 (AE004567) erythronate-4-phosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 377/380 (99%), Positives = 378/380 (99%)
Sequence:
ATGCGTATTCTCGCCGATGAAAACATTCCCGTGGTCGACGCCTTCTTCGCCGACCAGGGCTCCATTCGCCGC
TTGCCCGGGCGCGCCATCGACCGCGCGGCGCTGGCCGAGGTCGACGTGCTGCTGGTGCGCTCGGTCACCGAG
GTCAGCCGCGCCGCGCTGGCCGGCTCGCCGGTGCGCTTCGTCGGCACCTGCACCATCGGCACCGACCACCTC
GACCTCGACTACTTCGCCGAGGCTGGCATCGCCTGGTCCAGCGCGCCCGGCTGCAACGCCCGTGGGGTGGTG
GACTACGTGCTCGGCTGCCTGCTGGCGATGGCCGAGGTGCGCGGCGCCGACCTGGCCGAACGCACCTATGGG
GTGGTCGGCGCTGGGCAGGTCGGTGGGCGGCTGGTGGAGGTGCTGCGCGGGCTGGGCTGGAAAGTGCTGGTC
TGCGATCCGCCGCGCCAGGCACGCGAGCCGGACGGCGAATTCGTCTCGCTGGAACGGCTGCTGGCCGAGGCC
GACGTGATCAGCCTGCACACTCCGCTGAACCGCGACGGCGAACACCCGACCCGCCACCTGCTGGATGAACCC
CGCCTGGCCGCCCTGCGTCCCGGCACTTGGCTGGTCAACGCCAGCCGTGGCGCGGTGGTCGACAACCAGGCC
CTGCGCCGCCTGCTCGAAGGCGGCGCCGACCTGGAAGTGGCGCTGGACGTCTGGGAAGGCGAACCGCAGGCC
GACCCCGAACTGGCCGCGCACTGCCTGATCGCCACCCCGCACATCGCCGGCTACAGCCTGGAAGGCAAGCTG
CGCGGCACCGCGCAGATCTACCAGGCCTACTGCGCCTGGCGCGGCATCGCCGAACGTGTGAGCCTGCAAGAC
GTGCTGCCGGAAACCTGGCTCGCCGGCCTGCAACTCAACCCCGGCTGCGACCCGGCCTGGGCGCTGGCCACG
CTGTGCCGCGCGGTATACGACCCGCGCAGCGACGATGCCGCCTTCCGCCGCAGCCTGACCGGCGACAGCGCC
ACCCGCCGCGCCGCCTTCGACGCCCTGCGCAAACACTACCCGCCGCGCCGCGAGATCACCGGCCTGCGCGTC
GCCACCGGTGGGCGGGTGGAGTTGCAGCGGGTGGTGCGGGCGCTGGGGGCGCAGTTGGTCTAG
Translation:
MRILADENIPVVDAFFADQGSIRRLPGRAIDRAALAEVDVLLVRSVTEVSRAALAGSPVRFVGTCTIGTDHL
DLDYFAEAGIAWSSAPGCNARGVVDYVLGCLLAMAEVRGADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLV
CDPPRQAREPDGEFVSLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQA
LRRLLEGGADLEVALDVWEGEPQADPELAAHCLIATPHIAGYSLEGKLRGTAQIYQAYCAWRGIAERVSLQD
VLPETWLAGLQLNPGCDPAWALATLCRAVYDPRSDDAAFRRSLTGDSATRRAAFDALRKHYPPRREITGLRV
ATGGRVELQRVVRALGAQLV*
AnnotationID:1678GeneID:1669
AnnotatorUID: diggins
Modification Date/Time: 2005-04-27 09:09:05
Gene Name:pdxB
Confidence Code:2
GeneProduct:erythronate-4-phosphate dehydrogenase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0111
Secondary Functional Category(ies):
EC Number:1.1.1.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO55537.1| (AE016863) erythronate-4-phosphate dehydrogenase [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 380

 Score =  510 bits (1314), Expect = e-144
 Identities = 256/378 (67%), Positives = 298/378 (78%), Gaps = 2/378 (0%)

>gb|AAN67730.1|AE016404_5 (AE016782) erythronate-4-phosphate dehydrogenase [Pseudomonas
           putida KT2440]
          Length = 380

 Score =  492 bits (1267), Expect = e-138
 Identities = 253/381 (66%), Positives = 294/381 (77%), Gaps = 2/381 (0%)

>gb|AAN81317.1|AE016763_276 (AE016763) Erythronate-4-phosphate dehydrogenase [Escherichia coli
           CFT073]
          Length = 378

 Score =  316 bits (810), Expect = 1e-85
 Identities = 174/360 (48%), Positives = 223/360 (61%), Gaps = 6/360 (1%)






 
Structural Features:
COG0111, SerA, Phosphoglycerate dehydrogenase and related dehydrogenases 
[Amino acid transport and metabolism]
CD-Length = 324 residues,  96.6% aligned
Score =  192 bits (489), Expect = 6e-50
Identities = 104/318 (32%), Positives = 152/318 (47%), Gaps = 37/318 (11%)








   
Genomic Context:






   
Comment:


















    ReferenceID:3341




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20488




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37399




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1669_cdd.html


    		




 
URL:

















    ReferenceID:38003




  
Author/Investigator(s):
        Arps PJ, Winkler ME.





  
Title:
        Structural analysis of the Escherichia coli K-12 hisT operon by using a kanamycin resistance cassette.




  
PubMed:
        3029016


MedLine:
        




    
Source:
J Bacteriol. 1987 Mar;169(3):1061-70.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=3029016

















    ReferenceID:38004




  
Author/Investigator(s):
        Schoenlein PV, Roa BB, Winkler ME.





  
Title:
        Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12.




  
PubMed:
        2681152


MedLine:
        




    
Source:
J Bacteriol. 1989 Nov;171(11):6084-92.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2681152









           
Homologs By Global Alignment 

           

       



     
Gene ID:1669
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2938
                           PA1375_tr
                           translation of PA1375
                           380
                           99.21
                           99.47
                           0
                           1947.0
     

     
     
91552
                           gb|AAG04764.1|AE004567_3
                           (AE004567) erythronate-4-phosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
                           380
                           99.21
                           99.47
                           0
                           1947.0
     

     
     
91553
                           gb|AAO55537.1|
                           (AE016863) erythronate-4-phosphate dehydrogenase [Pseudomonas syringae pv. tomato str. DC3000]
                           381
                           67.45
                           78.47
                           2
                           1318.0
     

     
     
91554
                           gb|AAN67730.1|AE016404_5
                           (AE016782) erythronate-4-phosphate dehydrogenase [Pseudomonas putida KT2440]
                           381
                           66.40
                           77.16
                           2
                           1271.0
     

     
     
91568
                           emb|CAC93002.1|
                           (AJ414153) putative D-isomer specific 2-hydroxyacid dehydrogenase [Yersinia pestis CO92]
                           386
                           46.11
                           59.58
                           17
                           790.0
     

     






      

          
GC ORFID: 44671How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1375Glimmer Score: 

          
Start: 817628Stop: 818770

          
Length: 1143


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA1375 translation of PA1375Homolog Bit Score 754.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene837 (ORF: BLASTX 511.0), t_PA1375 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGTATTCTCGCCGATGAAAACATTCCCGTGGTCGACGCCTTCTTCGCCGACCAGGGCTCCATTCGCCGC 
TTGCCCGGGCGCGCCATCGACCGCGCGGCGCTGGCCGAGGTCGACGTGCTGCTGGTGCGCTCGGTCACCGAG 
GTCAGCCGCGCCGCGCTGGCCGGCTCGCCGGTGCGCTTCGTCGGCACCTGCACCATCGGCACCGACCACCTC 
GACCTCGACTACTTCGCCGAGGCTGGCATCGCCTGGTCCAGCGCGCCCGGCTGCAACGCCCGTGGGGTGGTG 
GACTACGTGCTCGGCTGCCTGCTGGCGATGGCCGAGGTGCGCGGCGCCGACCTGGCCGAACGCACCTATGGG 
GTGGTCGGCGCTGGGCAGGTCGGTGGGCGGCTGGTGGAGGTGCTGCGCGGGCTGGGCTGGAAAGTGCTGGTC 
TGCGATCCGCCGCGCCAGGCACGCGAGCCGGACGGCGAATTCGTCTCGCTGGAACGGCTGCTGGCCGAGGCC 
GACGTGATCAGCCTGCACACTCCGCTGAACCGCGACGGCGAACACCCGACCCGCCACCTGCTGGATGAACCC 
CGCCTGGCCGCCCTGCGTCCCGGCACTTGGCTGGTCAACGCCAGCCGTGGCGCGGTGGTCGACAACCAGGCC 
CTGCGCCGCCTGCTCGAAGGCGGCGCCGACCTGGAAGTGGCGCTGGACGTCTGGGAAGGCGAACCGCAGGCC 
GACCCCGAACTGGCCGCGCACTGCCTGATCGCCACCCCGCACATCGCCGGCTACAGCCTGGAAGGCAAGCTG 
CGCGGCACCGCGCAGATCTACCAGGCCTACTGCGCCTGGCGCGGCATCGCCGAACGTGTGAGCCTGCAAGAC 
GTGCTGCCGGAAACCTGGCTCGCCGGCCTGCAACTCAACCCCGGCTGCGACCCGGCCTGGGCGCTGGCCACG 
CTGTGCCGCGCGGTATACGACCCGCGCAGCGACGATGCCGCCTTCCGCCGCAGCCTGACCGGCGACAGCGCC 
ACCCGCCGCGCCGCCTTCGACGCCCTGCGCAAACACTACCCGCCGCGCCGCGAGATCACCGGCCTGCGCGTC 
GCCACCGGTGGGCGGGTGGAGTTGCAGCGGGTGGTGCGGGCGCTGGGGGCGCAGTTGGTCTAG