ViewGene
Locus Name:
GeneID:
Location:

GeneID:16
TrivialName: PA14_08780
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_08780
PAO1 Ortholog Locus:PA4269
Sequence Length:4200
Protein Length:1399
Start: 750342
Stop: 754541
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07657.1|AE004842_6 (AE004842) DNA-directed RNA polymerase beta* chain [Pseudomonas aeruginosa PAO1]
Identities = 1399/1399 (100%), Positives = 1399/1399 (100%)
Sequence:
TTGAAAGACTTGCTTAATCTGTTGAAAAACCAGGGTCAAATCGAAGAGTTCGATGCCATCCGTATTGGCCTG
GCTTCGCCCGAGATGATTCGTTCCTGGTCTTTCGGCGAAGTTAAAAAGCCGGAAACCATCAACTACCGTACC
TTCAAGCCGGAGCGCGACGGCCTGTTCTGCGCCAAGATCTTCGGCCCGGTGAAGGACTACGAGTGCCTGTGC
GGCAAGTACAAGCGCCTCAAGCACCGCGGTGTGATCTGCGAGAAGTGCGGCGTGGAAGTCGCCCTGGCCAAG
GTGCGCCGCGAGCGCATGGGCCACATCGAGCTGGCTTCGCCGGTTGCCCACATCTGGTTCCTGAAGTCGCTG
CCGTCCCGTATCGGCCTGCTGCTGGACATGACCCTGCGCGATATCGAGCGCGTGCTCTATTTCGAGAGCTAC
GTGGTGATCGATCCGGGCATGACCACTCTGGAAAAGGGCCAACTGCTGAACGACGAGCAATACTTCGAGGCC
CTCGAAGAGTTCGGTGACGATTTCGATGCTCGCATGGGCGCCGAAGCCGTTCACGAACTGCTCAACGCCATC
GACCTGGAGCACGAGATCGGCCGCCTGCGCGAAGAGATTCCGCAGACCAACTCGGAAACCAAGATCAAGAAG
CTGTCCAAGCGCCTGAAGCTGATGGAAGCCTTCCAGGGCTCCGGCAACAAGCCTGAGTGGATGGTCCTGACC
GTCCTGCCGGTGCTGCCGCCGGACCTGCGTCCGCTGGTTCCGCTGGATGGCGGTCGCTTCGCGACTTCCGAC
CTGAACGACCTATATCGTCGGGTGATCAACCGTAACAACCGTCTGAAGCGCCTGCTCGACCTGGCCGCTCCG
GACATCATCGTGCGCAACGAAAAGCGCATGCTGCAGGAAGCCGTCGACGCCCTGCTCGACAACGGCCGTCGC
GGTCGCGCCATCACCGGCTCGAACAAGCGTCCGCTGAAGTCGCTGGCCGACATGATCAAGGGCAAGCAAGGT
CGCTTCCGTCAGAACCTGCTCGGCAAGCGCGTGGACTACTCCGGTCGTTCCGTGATCACCGTGGGCCCGACC
CTGCGCCTGCACCAGTGCGGTCTGCCGAAGAAGATGGCCCTGGAGCTGTTCAAGCCGTTCATCTTCGGCAAG
CTGGAAGGTCGTGGCATGGCCACCACCATCAAGGCCGCCAAGAAAATGGTCGAGCGCGAGCTGCCCGAGGTC
TGGGACGTTCTCGCCGAAGTTATCCGCGAGCATCCGGTTCTCCTGAACCGTGCGCCGACCCTGCACCGTCTG
GGCATCCAGGCGTTCGAGCCGGTCCTCATCGAAGGCAAGGCGATCCAGCTGCACCCGCTGGTCTGCGCCGCG
TACAACGCCGACTTCGACGGTGACCAGATGGCCGTCCACGTTCCGCTGACCCTCGAGGCCCAGCTGGAAGCG
CGCGCGCTGATGATGTCCACCAACAACATCCTGTCGCCCGCCAACGGCGAGCCGATCATCGTTCCGTCGCAG
GACGTGGTAATGGGTCTGTACTACATGACCCGTGAAGCGATCAACGCGAAGGGCGAGGGCATGGCCTTCGCC
GACCTGCAGGAAGTCGACCGCGCCTACCGCAGCGGCCAGGCGTCCCTGCACGCTCGTGTGAAAGTGCGCATC
AACGAAAAGATCAAGGGTGAAGACGGCCAACTGACCGCCAATACCCGTATCGTCGACACCACCGTCGGCCGC
GCGCTGCTGTTCCAGGTCGTTCCGGCCGGCCTGCCGTTCGACGTGGTCAACCAGTCGATGAAGAAGAAGGCG
ATCTCCAAGCTGATCAACCACTGCTATCGCGTGGTGGGTCTGAAGGACACCGTCATCTTCGCCGACCAGCTG
ATGTACACCGGTTTCGCCTACTCGACCATTTCCGGCGTGTCCATCGGCGTCAACGACTTCGTCATCCCGGAC
GAAAAGGCGCGGATCATCAACGCCGCCACCGACGAAGTGAAGGAGATCGAGAGCCAGTACGCCTCCGGCCTG
GTAACCCAGGGCGAGAAGTACAACAAGGTGATCGACCTGTGGTCGAAGGCCAACGACGAAGTGTCCAAGGCG
ATGATGGCCAACCTCTCGAAAGAGAAGGTCGTCGATCGCGAGGGCAAGGAAGTCGATCAGGAGTCCTTCAAC
TCCATGTACATGATGGCTGACTCGGGTGCGCGGGGCTCCGCGGCCCAGATCCGTCAGCTGGCAGGTATGCGT
GGTCTGATGGCCAAGCCGGACGGCTCGATCATCGAGACCCCGATCACCGCGAACTTCCGGGAAGGCCTGAAC
GTACTCCAGTACTTCATCTCCACCCACGGTGCTCGTAAGGGTCTGGCGGATACCGCGCTGAAGACCGCGAAC
TCCGGTTACCTGACCCGTCGTCTGGTCGACGTGGCCCAGGATCTGGTAGTGACCGAGATCGATTGCGGTACC
GAGCACGGCCTGCTGATGTCGCCGCACATCGAAGGCGGCGACGTGGTCGAACCGCTCGGCGAGCGCGTGCTC
GGCCGTGTGATCGCGCGCGACGTGTTCAAGCCGGGCAGCGACGAGGTCATCGTGCCGGCCGGCACCCTGATC
GACGAGAAGTGGGTCGACTTCCTCGAAGTGATGAGCGTCGACGAAGTGGTGGTGCGTTCCCCGATCACCTGC
GAAACCCGTCATGGCATCTGCGCCATGTGCTACGGCCGCGACCTGGCCCGTGGCCATCGCGTCAACATCGGC
GAGGCGGTCGGTGTCATCGCTGCCCAGTCCATCGGTGAGCCGGGCACCCAGCTGACCATGCGTACCTTCCAC
ATCGGCGGTGCGGCCAGCCGGACCTCCGCGGCCGACAACGTCCAGGTGAAGAACGGCGGTACCATCCGCCTG
CACAACCTGAAGCATGTGGTTCGTGCCGACGGCGCGCTGGTCGCGGTTTCCCGTTCCGGCGAACTGGCGGTT
GCCGACGACTTCGGTCGCGAGCGCGAGCGCTACAAGCTGCCGTACGGTGCGGTGATCTCGGTCAAGGAAGGT
GACAAGGTCGACCCGGGCGCCATCGTCGCCAAGTGGGACCCGCACACCCACCCGATCGTCACCGAGGTGGAC
GGTACCGTGGCCTTCGTGGGCATGGAAGAGGGCATCACCGTCAAGCGTCAGACCGACGAACTGACCGGCCTG
ACCAACATCGAAGTGATGGATCCGAAGGACCGTCCGGCTGCCGGCAAGGACATCCGTCCGGCCGTGAAGCTG
ATCGATGCCGCGGGCAAGGACCTGCTGCTGCCGGGTACCGACGTACCGGCGCAGTACTTCCTGCCGGCCAAC
GCCCTGGTCAACCTGACCGACGGCGCCAAGGTGAGCATCGGTGACGTTGTCGCGCGTATCCCGCAGGAAACC
TCGAAGACCCGTGACATCACCGGTGGTCTGCCGCGCGTTGCCGACCTGTTCGAGGCTCGTCGTCCGAAAGAG
CCTTCGATCCTGGCGGAAATCAGCGGCACCATCTCCTTCGGCAAGGAGACCAAGGGCAAGCGCCGCCTGGTC
ATCACGCCGAACGATGGCAGCGATCCGTACGAGGAGCTGATTCCGAAGTGGCGTCACCTGAACGTGTTCGAA
GGCGAACAGGTGAACCGCGGCGAAGTCATCTCCGACGGTCCGAGCAACCCGCACGACATCCTGCGCCTGCTG
GGCGTGAGCTCGCTGGCGAAGTACATCGTCAACGAGATCCAGGACGTCTACCGTCTGCAGGGCGTGAAAATC
AACGACAAGCACATCGAGACCATCCTGCGTCAGATGCTGCGCAAGGTCGAAGTCAGTGAGTCCGGCGACTCC
AGCTTCATCAAAGGCGACCAGGTGGAACTCACCCAGGTGCTGGAAGAGAACGAACAGCTCGGTACCGAGGAC
AAGTTCCCGGCCAAGTACGAGCGGGTTCTGCTGGGTATCACCAAGGCCTCCCTGTCGACCGAGTCGTTCATT
TCCGCGGCGTCGTTCCAGGAGACCACCCGCGTCCTCACCGAGGCGGCGGTCACCGGCAAGCGCGACTTCCTG
CGTGGTCTGAAAGAGAACGTGGTCGTGGGTCGCCTGATCCCGGCCGGTACCGGTCTGGCTTACCACAGCGAG
CGCAAGCGTCAGCGCGACCTCGGCAAGCCGCAGCGTGTGAGTGCCAGCGAGGCGGAAGCCGCACTGACCGAA
GCGCTGAACTCGAGCGGTAACTAA
Translation:
MKDLLNLLKNQGQIEEFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLC
GKYKRLKHRGVICEKCGVEVALAKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESY
VVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVHELLNAIDLEHEIGRLREEIPQTNSETKIKK
LSKRLKLMEAFQGSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAP
DIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
LRLHQCGLPKKMALELFKPFIFGKLEGRGMATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRL
GIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQ
DVVMGLYYMTREAINAKGEGMAFADLQEVDRAYRSGQASLHARVKVRINEKIKGEDGQLTANTRIVDTTVGR
ALLFQVVPAGLPFDVVNQSMKKKAISKLINHCYRVVGLKDTVIFADQLMYTGFAYSTISGVSIGVNDFVIPD
EKARIINAATDEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVVDREGKEVDQESFN
SMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTAN
SGYLTRRLVDVAQDLVVTEIDCGTEHGLLMSPHIEGGDVVEPLGERVLGRVIARDVFKPGSDEVIVPAGTLI
DEKWVDFLEVMSVDEVVVRSPITCETRHGICAMCYGRDLARGHRVNIGEAVGVIAAQSIGEPGTQLTMRTFH
IGGAASRTSAADNVQVKNGGTIRLHNLKHVVRADGALVAVSRSGELAVADDFGRERERYKLPYGAVISVKEG
DKVDPGAIVAKWDPHTHPIVTEVDGTVAFVGMEEGITVKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAVKL
IDAAGKDLLLPGTDVPAQYFLPANALVNLTDGAKVSIGDVVARIPQETSKTRDITGGLPRVADLFEARRPKE
PSILAEISGTISFGKETKGKRRLVITPNDGSDPYEELIPKWRHLNVFEGEQVNRGEVISDGPSNPHDILRLL
GVSSLAKYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEVSESGDSSFIKGDQVELTQVLEENEQLGTED
KFPAKYERVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDFLRGLKENVVVGRLIPAGTGLAYHSE
RKRQRDLGKPQRVSASEAEAALTEALNSSGN*
AnnotationID:26GeneID:16
AnnotatorUID: diggins
Modification Date/Time: 2005-04-03 17:05:44
Gene Name:rpoC
Confidence Code:2
GeneProduct:DNA-directed RNA polymerase beta* chain
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(24) Transcription, RNA processing and degradation
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0086,smart00663,pfam04998,pfam04997
Secondary Functional Category(ies):
EC Number:2.7.7.6
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO54162.1| (AE016858) DNA-directed RNA polymerase, beta' subunit [Pseudomonas
            syringae pv. tomato str. DC3000]
          Length = 1399

 Score = 2568 bits (6656), Expect = 0.0
 Identities = 1290/1399 (92%), Positives = 1356/1399 (96%)

>gb|AAN66078.1|AE016237_2 (AE016775) DNA-directed RNA polymerase, beta' subunit [Pseudomonas
            putida KT2440]
          Length = 1399

 Score = 2565 bits (6648), Expect = 0.0
 Identities = 1290/1399 (92%), Positives = 1355/1399 (96%)

>gb|AAN53310.1|AE015472_2 (AE015472) DNA-directed RNA polymerase, beta' subunit [Shewanella
            oneidensis MR-1]
          Length = 1405

 Score = 2143 bits (5552), Expect = 0.0
 Identities = 1070/1403 (76%), Positives = 1220/1403 (86%), Gaps = 4/1403 (0%)






 
Structural Features:
COG0086, RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription] 
CD-Length = 808 residues,  99.3% aligned
Score =  922 bits (2384), Expect = 0.0
Identities = 450/861 (52%), Positives = 532/861 (61%), Gaps = 86/861 (9%)

smart00663, RPOLA_N, RNA polymerase I subunit A N-terminus
CD-Length = 305 residues, 100.0% aligned
Score =  399 bits (1026), Expect = 1e-111
Identities = 155/305 (50%), Positives = 193/305 (63%), Gaps = 25/305 (8%)

pfam04998, RNA_pol_Rpb1_5, RNA polymerase Rpb1, domain 5. 
CD-Length = 546 residues, 100.0% aligned
Score =  337 bits (864), Expect = 6e-93
Identities = 156/602 (25%), Positives = 227/602 (37%), Gaps = 101/602 (16%)

pfam04997, RNA_pol_Rpb1_1, RNA polymerase Rpb1, domain 1.
CD-Length = 334 residues, 100.0% aligned
Score =  328 bits (843), Expect = 3e-90
Identities = 139/353 (39%), Positives = 181/353 (51%), Gaps = 43/353 (12%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14029




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17177




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36638




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:16_cdd.html


    		




 
URL:

















    ReferenceID:36770




  
Author/Investigator(s):
        Ovchinnikov YuA, Monastyrskaya GS, Gubanov VV, Guryev SO, Salomatina IS, Shuvaeva TM, Lipkin VM, Sverdlov ED.





  
Title:
        The primary structure of E. coli RNA polymerase, Nucleotide sequence of the rpoC gene and amino acid sequence of the beta'-subunit.




  
PubMed:
        6287430


MedLine:
        




    
Source:
Nucleic Acids Res. 1982 Jul 10;10(13):4035-44.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6287430

















    ReferenceID:36771




  
Author/Investigator(s):
        Squires C, Krainer A, Barry G, Shen WF, Squires CL.





  
Title:
        Nucleotide sequence at the end of the gene for the RNA polymerase beta' subunit (rpoC).




  
PubMed:
        6278450


MedLine:
        




    
Source:
Nucleic Acids Res. 1981 Dec 21;9(24):6827-40.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6278450

















    ReferenceID:36773




  
Author/Investigator(s):
        Newman A, Hayward RS.





  
Title:
        Cloning of DNA of the rpoBC operon from the chromosome of Escherichia coli K12.




  
PubMed:
        6246404


MedLine:
        




    
Source:
Mol Gen Genet. 1980 Feb;177(3):527-33.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6246404









           
Homologs By Global Alignment 

           

       



     
Gene ID:16
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
37
                           PA4269_tr
                           translation of PA4269
                           1399
                           99.99
                           99.99
                           0
                           7108.0
     

     
     
8736
                           gb|AAG07657.1|AE004842_6
                           (AE004842) DNA-directed RNA polymerase beta* chain [Pseudomonas aeruginosa PAO1]
                           1399
                           99.92
                           99.99
                           0
                           7106.0
     

     
     
8737
                           gb|AAO54162.1|
                           (AE016858) DNA-directed RNA polymerase, beta' subunit [Pseudomonas syringae pv. tomato str. DC3000]
                           1399
                           92.13
                           96.92
                           0
                           6653.0
     

     
     
8738
                           gb|AAN66078.1|AE016237_2
                           (AE016775) DNA-directed RNA polymerase, beta' subunit [Pseudomonas putida KT2440]
                           1399
                           92.13
                           96.85
                           0
                           6645.0
     

     
     
8739
                           emb|CAA34538.1|
                           (X16538) beta'-subunit of RNA polymerase [Pseudomonas putida]
                           1411
                           87.81
                           92.70
                           14
                           6306.0
     

     






      

          
GC ORFID: 43018How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4269Glimmer Score: 

          
Start: 4203597Stop: 4199398

          
Length: 4200


          
Start Codon: TTGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA4269 translation of PA4269Homolog Bit Score 2742.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene86 (ORF: BLASTX 2568.0), t_PA4269 (ORF: GLIMMER)

          
GC ORF Sequence

           
TTGAAAGACTTGCTTAATCTGTTGAAAAACCAGGGTCAAATCGAAGAGTTCGATGCCATCCGTATTGGCCTG 
GCTTCGCCCGAGATGATTCGTTCCTGGTCTTTCGGCGAAGTTAAAAAGCCGGAAACCATCAACTACCGTACC 
TTCAAGCCGGAGCGCGACGGCCTGTTCTGCGCCAAGATCTTCGGCCCGGTGAAGGACTACGAGTGCCTGTGC 
GGCAAGTACAAGCGCCTCAAGCACCGCGGTGTGATCTGCGAGAAGTGCGGCGTGGAAGTCGCCCTGGCCAAG 
GTGCGCCGCGAGCGCATGGGCCACATCGAGCTGGCTTCGCCGGTTGCCCACATCTGGTTCCTGAAGTCGCTG 
CCGTCCCGTATCGGCCTGCTGCTGGACATGACCCTGCGCGATATCGAGCGCGTGCTCTATTTCGAGAGCTAC 
GTGGTGATCGATCCGGGCATGACCACTCTGGAAAAGGGCCAACTGCTGAACGACGAGCAATACTTCGAGGCC 
CTCGAAGAGTTCGGTGACGATTTCGATGCTCGCATGGGCGCCGAAGCCGTTCACGAACTGCTCAACGCCATC 
GACCTGGAGCACGAGATCGGCCGCCTGCGCGAAGAGATTCCGCAGACCAACTCGGAAACCAAGATCAAGAAG 
CTGTCCAAGCGCCTGAAGCTGATGGAAGCCTTCCAGGGCTCCGGCAACAAGCCTGAGTGGATGGTCCTGACC 
GTCCTGCCGGTGCTGCCGCCGGACCTGCGTCCGCTGGTTCCGCTGGATGGCGGTCGCTTCGCGACTTCCGAC 
CTGAACGACCTATATCGTCGGGTGATCAACCGTAACAACCGTCTGAAGCGCCTGCTCGACCTGGCCGCTCCG 
GACATCATCGTGCGCAACGAAAAGCGCATGCTGCAGGAAGCCGTCGACGCCCTGCTCGACAACGGCCGTCGC 
GGTCGCGCCATCACCGGCTCGAACAAGCGTCCGCTGAAGTCGCTGGCCGACATGATCAAGGGCAAGCAAGGT 
CGCTTCCGTCAGAACCTGCTCGGCAAGCGCGTGGACTACTCCGGTCGTTCCGTGATCACCGTGGGCCCGACC 
CTGCGCCTGCACCAGTGCGGTCTGCCGAAGAAGATGGCCCTGGAGCTGTTCAAGCCGTTCATCTTCGGCAAG 
CTGGAAGGTCGTGGCATGGCCACCACCATCAAGGCCGCCAAGAAAATGGTCGAGCGCGAGCTGCCCGAGGTC 
TGGGACGTTCTCGCCGAAGTTATCCGCGAGCATCCGGTTCTCCTGAACCGTGCGCCGACCCTGCACCGTCTG 
GGCATCCAGGCGTTCGAGCCGGTCCTCATCGAAGGCAAGGCGATCCAGCTGCACCCGCTGGTCTGCGCCGCG 
TACAACGCCGACTTCGACGGTGACCAGATGGCCGTCCACGTTCCGCTGACCCTCGAGGCCCAGCTGGAAGCG 
CGCGCGCTGATGATGTCCACCAACAACATCCTGTCGCCCGCCAACGGCGAGCCGATCATCGTTCCGTCGCAG 
GACGTGGTAATGGGTCTGTACTACATGACCCGTGAAGCGATCAACGCGAAGGGCGAGGGCATGGCCTTCGCC 
GACCTGCAGGAAGTCGACCGCGCCTACCGCAGCGGCCAGGCGTCCCTGCACGCTCGTGTGAAAGTGCGCATC 
AACGAAAAGATCAAGGGTGAAGACGGCCAACTGACCGCCAATACCCGTATCGTCGACACCACCGTCGGCCGC 
GCGCTGCTGTTCCAGGTCGTTCCGGCCGGCCTGCCGTTCGACGTGGTCAACCAGTCGATGAAGAAGAAGGCG 
ATCTCCAAGCTGATCAACCACTGCTATCGCGTGGTGGGTCTGAAGGACACCGTCATCTTCGCCGACCAGCTG 
ATGTACACCGGTTTCGCCTACTCGACCATTTCCGGCGTGTCCATCGGCGTCAACGACTTCGTCATCCCGGAC 
GAAAAGGCGCGGATCATCAACGCCGCCACCGACGAAGTGAAGGAGATCGAGAGCCAGTACGCCTCCGGCCTG 
GTAACCCAGGGCGAGAAGTACAACAAGGTGATCGACCTGTGGTCGAAGGCCAACGACGAAGTGTCCAAGGCG 
ATGATGGCCAACCTCTCGAAAGAGAAGGTCGTCGATCGCGAGGGCAAGGAAGTCGATCAGGAGTCCTTCAAC 
TCCATGTACATGATGGCTGACTCGGGTGCGCGGGGCTCCGCGGCCCAGATCCGTCAGCTGGCAGGTATGCGT 
GGTCTGATGGCCAAGCCGGACGGCTCGATCATCGAGACCCCGATCACCGCGAACTTCCGGGAAGGCCTGAAC 
GTACTCCAGTACTTCATCTCCACCCACGGTGCTCGTAAGGGTCTGGCGGATACCGCGCTGAAGACCGCGAAC 
TCCGGTTACCTGACCCGTCGTCTGGTCGACGTGGCCCAGGATCTGGTAGTGACCGAGATCGATTGCGGTACC 
GAGCACGGCCTGCTGATGTCGCCGCACATCGAAGGCGGCGACGTGGTCGAACCGCTCGGCGAGCGCGTGCTC 
GGCCGTGTGATCGCGCGCGACGTGTTCAAGCCGGGCAGCGACGAGGTCATCGTGCCGGCCGGCACCCTGATC 
GACGAGAAGTGGGTCGACTTCCTCGAAGTGATGAGCGTCGACGAAGTGGTGGTGCGTTCCCCGATCACCTGC 
GAAACCCGTCATGGCATCTGCGCCATGTGCTACGGCCGCGACCTGGCCCGTGGCCATCGCGTCAACATCGGC 
GAGGCGGTCGGTGTCATCGCTGCCCAGTCCATCGGTGAGCCGGGCACCCAGCTGACCATGCGTACCTTCCAC 
ATCGGCGGTGCGGCCAGCCGGACCTCCGCGGCCGACAACGTCCAGGTGAAGAACGGCGGTACCATCCGCCTG 
CACAACCTGAAGCATGTGGTTCGTGCCGACGGCGCGCTGGTCGCGGTTTCCCGTTCCGGCGAACTGGCGGTT 
GCCGACGACTTCGGTCGCGAGCGCGAGCGCTACAAGCTGCCGTACGGTGCGGTGATCTCGGTCAAGGAAGGT 
GACAAGGTCGACCCGGGCGCCATCGTCGCCAAGTGGGACCCGCACACCCACCCGATCGTCACCGAGGTGGAC 
GGTACCGTGGCCTTCGTGGGCATGGAAGAGGGCATCACCGTCAAGCGTCAGACCGACGAACTGACCGGCCTG 
ACCAACATCGAAGTGATGGATCCGAAGGACCGTCCGGCTGCCGGCAAGGACATCCGTCCGGCCGTGAAGCTG 
ATCGATGCCGCGGGCAAGGACCTGCTGCTGCCGGGTACCGACGTACCGGCGCAGTACTTCCTGCCGGCCAAC 
GCCCTGGTCAACCTGACCGACGGCGCCAAGGTGAGCATCGGTGACGTTGTCGCGCGTATCCCGCAGGAAACC 
TCGAAGACCCGTGACATCACCGGTGGTCTGCCGCGCGTTGCCGACCTGTTCGAGGCTCGTCGTCCGAAAGAG 
CCTTCGATCCTGGCGGAAATCAGCGGCACCATCTCCTTCGGCAAGGAGACCAAGGGCAAGCGCCGCCTGGTC 
ATCACGCCGAACGATGGCAGCGATCCGTACGAGGAGCTGATTCCGAAGTGGCGTCACCTGAACGTGTTCGAA 
GGCGAACAGGTGAACCGCGGCGAAGTCATCTCCGACGGTCCGAGCAACCCGCACGACATCCTGCGCCTGCTG 
GGCGTGAGCTCGCTGGCGAAGTACATCGTCAACGAGATCCAGGACGTCTACCGTCTGCAGGGCGTGAAAATC 
AACGACAAGCACATCGAGACCATCCTGCGTCAGATGCTGCGCAAGGTCGAAGTCAGTGAGTCCGGCGACTCC 
AGCTTCATCAAAGGCGACCAGGTGGAACTCACCCAGGTGCTGGAAGAGAACGAACAGCTCGGTACCGAGGAC 
AAGTTCCCGGCCAAGTACGAGCGGGTTCTGCTGGGTATCACCAAGGCCTCCCTGTCGACCGAGTCGTTCATT 
TCCGCGGCGTCGTTCCAGGAGACCACCCGCGTCCTCACCGAGGCGGCGGTCACCGGCAAGCGCGACTTCCTG 
CGTGGTCTGAAAGAGAACGTGGTCGTGGGTCGCCTGATCCCGGCCGGTACCGGTCTGGCTTACCACAGCGAG 
CGCAAGCGTCAGCGCGACCTCGGCAAGCCGCAGCGTGTGAGTGCCAGCGAGGCGGAAGCCGCACTGACCGAA 
GCGCTGAACTCGAGCGGTAACTAA