ViewGene
Locus Name:
GeneID:
Location:

GeneID:1455
TrivialName: PA14_43690
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_43690
PAO1 Ortholog Locus:PA1609
Sequence Length:1218
Protein Length:405
Start: 3890617
Stop: 3891834
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04998.1|AE004589_1 (AE004589) beta-ketoacyl-ACP synthase I [Pseudomonas aeruginosa PAO1]
Identities = 404/405 (99%), Positives = 404/405 (99%)
Sequence:
ATGCGTCGCGTCGTTATCACCGGTCTGGGCATCGTTTCCTGCCTCGGCAATGACAAAGACACCGTTTCCGCC
AACCTCCGTGCGGGTCGGCCCGGCATTCGCTTCAATCCGTCCTACGCCGAGATGGGCCTGCGCAGCCACGTT
TCCGGTTCGGTCGACCTGAACCTCGAAGAGCTGATCGATCGCAAGGTCTTCCGCTTCATGGGCGATGCCGCC
GCTTACGCCTACCTGGCGATGGAGCAGGCGATCAAGGACTCCGGCCTGACTCCGGAACAGATTTCCAACCCC
CGCACCGGCCTGATCGCCGGCTCCGGCGGCGCTTCCACCCTGAACCAGATGGAAGCCATCGACACCCTGCGC
GAGAAAGGCGTCAAACGCATCGGCCCATACCGCGTGACCCGCACCATGGGCAGCACCGTATCGGCCTGCCTG
GCCACGCCGTTCCAGATCAAGGGCGTCAACTACTCGATCTCCTCCGCCTGCGCCACCAGCGCGCATTGCATC
GGCCAGGCCATGGAACAGATCCAGTTGGGCAAGCAGGACGTGGTCTTCGCCGGCGGCGGCGAAGAGGAACAC
TGGAGCCAGAGCTGCCTGTTCGACGCCATGGGCGCCCTCTCCACCCAGTACAACGAGACGCCGGAAAAGGCC
TCCCGCGCCTACGACGCCAAGCGTGACGGCTTCGTCATCGCCGGCGGCGGCGGCATGGTGGTGGTCGAGGAG
CTGGAGCATGCGCTCAAGCGCGGCGCCAAGATCTACGCCGAGATCGTCGGCTACGGCGCCACCTCCGACGGC
TACGACATGGTCGCCCCGAGCGGCGAAGGCGCGATCCGCTGCATGCAGCAGGCGCTGGCCACCGTCGACGCG
CCGATCGACTACCTGAACACCCACGGCACCTCCACCCCGGTCGGCGACGTCGCCGAGATCCGAGGCGTGCGC
GAAGTGTTCGGCGACAAGGCGCCGGCCATCAGCTCGACGAAGAGCCTGTCCGGCCACTCGCTGGGCGCCGCC
GGCGTACACGAGGCGATCTATTGCCTGCTGATGATGGAAGGCGGCTTCATCGCCGGCTCCGCCAACATCGAC
GAACTCGACCCGGAAGTGGCCGACCTGCCGATTCTCCGCGAGACCCGCGAGAACGCCAAGCTCGATACCGTC
ATGAGCAACAGCTTCGGCTTCGGCGGCACCAACGCCACCCTGGTCCTCAAGCGCTGGCAGGGTTGA
Translation:
MRRVVITGLGIVSCLGNDKDTVSANLRAGRPGIRFNPSYAEMGLRSHVSGSVDLNLEELIDRKVFRFMGDAA
AYAYLAMEQAIKDSGLTPEQISNPRTGLIAGSGGASTLNQMEAIDTLREKGVKRIGPYRVTRTMGSTVSACL
ATPFQIKGVNYSISSACATSAHCIGQAMEQIQLGKQDVVFAGGGEEEHWSQSCLFDAMGALSTQYNETPEKA
SRAYDAKRDGFVIAGGGGMVVVEELEHALKRGAKIYAEIVGYGATSDGYDMVAPSGEGAIRCMQQALATVDA
PIDYLNTHGTSTPVGDVAEIRGVREVFGDKAPAISSTKSLSGHSLGAAGVHEAIYCLLMMEGGFIAGSANID
ELDPEVADLPILRETRENAKLDTVMSNSFGFGGTNATLVLKRWQG*
AnnotationID:1464GeneID:1455
AnnotatorUID: diggins
Modification Date/Time: 2005-04-28 07:07:35
Gene Name:fabB
Confidence Code:1
GeneProduct:beta-ketoacyl-ACP synthase I
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:3-oxoacyl-(acyl-carrier-protein) synthase I
Functional Category Confidence Code:5
COGs:COG0304,cd00834,cd00825
Secondary Functional Category(ies):secondary metabolites, biosynthesis, transport, and catabolism
EC Number:2.3.1.41
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN69756.1|AE016612_2 (AE016789) 3-oxoacyl-(acyl-carrier-protein) synthase I [Pseudomonas
           putida KT2440]
          Length = 406

 Score =  724 bits (1868), Expect = 0.0
 Identities = 361/405 (89%), Positives = 381/405 (94%)

>gb|AAO55726.1| (AE016863) 3-oxoacyl-(acyl-carrier-protein) synthase I [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 407

 Score =  712 bits (1839), Expect = 0.0
 Identities = 357/406 (87%), Positives = 379/406 (93%), Gaps = 1/406 (0%)

>dbj|BAB36630.1| (AP002561) 3-oxoacyl-[acyl-carrier-protein] synthase I [Escherichia
           coli O157:H7]
          Length = 406

 Score =  550 bits (1418), Expect = e-156
 Identities = 283/404 (70%), Positives = 330/404 (81%), Gaps = 3/404 (0%)






 
Structural Features:
COG0304, FabB, 3-oxoacyl-(acyl-carrier-protein) synthase 
[Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]
CD-Length = 412 residues,  99.8% aligned
Score =  438 bits (1128), Expect = 5e-124
Identities = 200/413 (48%), Positives = 258/413 (62%), Gaps = 11/413 (2%)

cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), 
type I and II.
CD-Length = 406 residues, 100.0% aligned
Score =  426 bits (1098), Expect = 2e-120

cd00825, decarbox_cond_enzymes, decarboxylating condensing enzymes
CD-Length = 391 residues, 100.0% aligned
Score =  287 bits (735), Expect = 2e-78







   
Genomic Context:






   
Comment:


















    ReferenceID:2913




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:20057




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37901




  
Author/Investigator(s):
        Hoang TT, Schweizer HP.





  
Title:
        Fatty acid biosynthesis in Pseudomonas aeruginosa: cloning and characterization of the fabAB operon encoding beta-hydroxyacyl-acyl carrier protein dehydratase (FabA) and beta-ketoacyl-acyl carrier protein synthase I (FabB).




  
PubMed:
        9286984


MedLine:
        




    
Source:
J Bacteriol. 1997 Sep;179(17):5326-32.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=9286984

















    ReferenceID:38052




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1455_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1455
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2620
                           PA1609_tr
                           translation of PA1609
                           405
                           99.75
                           99.75
                           0
                           2064.0
     

     
     
81929
                           gb|AAG04998.1|AE004589_1
                           (AE004589) beta-ketoacyl-ACP synthase I [Pseudomonas aeruginosa PAO1]
                           405
                           99.75
                           99.75
                           0
                           2064.0
     

     
     
81930
                           gb|AAC45620.1|
                           (U70470) beta-ketoacyl-ACP synthase I [Pseudomonas aeruginosa]
                           405
                           98.76
                           99.01
                           0
                           2041.0
     

     
     
81931
                           gb|AAN69756.1|AE016612_2
                           (AE016789) 3-oxoacyl-(acyl-carrier-protein) synthase I [Pseudomonas putida KT2440]
                           406
                           88.91
                           93.84
                           1
                           1868.0
     

     
     
81932
                           gb|AAO55726.1|
                           (AE016863) 3-oxoacyl-(acyl-carrier-protein) synthase I [Pseudomonas syringae pv. tomato str. DC3000]
                           407
                           87.71
                           93.12
                           2
                           1841.0
     

     






      

          
GC ORFID: 44457How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1609Glimmer Score: 

          
Start: 1063292Stop: 1062075

          
Length: 1218


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1609 translation of PA1609Homolog Bit Score 799.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene427 (ORF: BLASTX 714.0), t_PA2965 (ORF: BLASTX 281.0), psyr_15may02_Scaffold16_revised_gene2610 (ORF: BLASTX 273.0), t_PA1609 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGTCGCGTCGTTATCACCGGTCTGGGCATCGTTTCCTGCCTCGGCAATGACAAAGACACCGTTTCCGCC 
AACCTCCGTGCGGGTCGGCCCGGCATTCGCTTCAATCCGTCCTACGCCGAGATGGGCCTGCGCAGCCACGTT 
TCCGGTTCGGTCGACCTGAACCTCGAAGAGCTGATCGATCGCAAGGTCTTCCGCTTCATGGGCGATGCCGCC 
GCTTACGCCTACCTGGCGATGGAGCAGGCGATCAAGGACTCCGGCCTGACTCCGGAACAGATTTCCAACCCC 
CGCACCGGCCTGATCGCCGGCTCCGGCGGCGCTTCCACCCTGAACCAGATGGAAGCCATCGACACCCTGCGC 
GAGAAAGGCGTCAAACGCATCGGCCCATACCGCGTGACCCGCACCATGGGCAGCACCGTATCGGCCTGCCTG 
GCCACGCCGTTCCAGATCAAGGGCGTCAACTACTCGATCTCCTCCGCCTGCGCCACCAGCGCGCATTGCATC 
GGCCAGGCCATGGAACAGATCCAGTTGGGCAAGCAGGACGTGGTCTTCGCCGGCGGCGGCGAAGAGGAACAC 
TGGAGCCAGAGCTGCCTGTTCGACGCCATGGGCGCCCTCTCCACCCAGTACAACGAGACGCCGGAAAAGGCC 
TCCCGCGCCTACGACGCCAAGCGTGACGGCTTCGTCATCGCCGGCGGCGGCGGCATGGTGGTGGTCGAGGAG 
CTGGAGCATGCGCTCAAGCGCGGCGCCAAGATCTACGCCGAGATCGTCGGCTACGGCGCCACCTCCGACGGC 
TACGACATGGTCGCCCCGAGCGGCGAAGGCGCGATCCGCTGCATGCAGCAGGCGCTGGCCACCGTCGACGCG 
CCGATCGACTACCTGAACACCCACGGCACCTCCACCCCGGTCGGCGACGTCGCCGAGATCCGAGGCGTGCGC 
GAAGTGTTCGGCGACAAGGCGCCGGCCATCAGCTCGACGAAGAGCCTGTCCGGCCACTCGCTGGGCGCCGCC 
GGCGTACACGAGGCGATCTATTGCCTGCTGATGATGGAAGGCGGCTTCATCGCCGGCTCCGCCAACATCGAC 
GAACTCGACCCGGAAGTGGCCGACCTGCCGATTCTCCGCGAGACCCGCGAGAACGCCAAGCTCGATACCGTC 
ATGAGCAACAGCTTCGGCTTCGGCGGCACCAACGCCACCCTGGTCCTCAAGCGCTGGCAGGGTTGA