ViewGene
Locus Name:
GeneID:
Location:

GeneID:1339
TrivialName: PA14_36310
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_36310
PAO1 Ortholog Locus:PA2195
Sequence Length:1254
Protein Length:417
Start: 3234672
Stop: 3233419
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05583.1|AE004646_4 (AE004646) hydrogen cyanide synthase HcnC [Pseudomonas aeruginosa PAO1]
Identities = 414/417 (99%), Positives = 416/417 (99%)
Sequence:
ATGAACAGAACCTATGACATCGTGATTGCCGGCGGCGGCGTGATCGGCGCGTCCTGCGCCTACCAACTGTCC
AGGCGCGGCAACCTGCGCATCGCCGTGGTCGACGACAAGCGACCGGGCAACGCCACCCGCGCCTCGGCCGGC
GGCCTCTGGGCCATCGGCGAATCGGTGGGGCTGGGCTGCGGGGTGATCTTCTTCCGCATGATGTCCTCCCGC
AACCGGCGCGAGGCCCAGGGCGCGGCGGTGGCGGTGGACGCGAGCACGCCGCACATCCTGCCGCCGGCGTTC
TTCGACCTCGCCCTGCAATCCAACGCGCTGTACCCGGAACTGCACCGAGAACTGATCGAACGCCACGGGATG
GACTTCAAGTTCGAGCGCACCGGCCTGAAATACGTGATCCAGGACGACGAGGATCGCCAGTACGCCGAGCAC
ATCGTGGCGCAGATCCCGCATCTGGCCGAGCAGGTACGCTGGCTGGACCGCGAGGAACTGCGTCGTGCCGAG
CCGGCGGTCAGCCACGCGGCCCACGGCGCGCTGGAATTCCTCTGCGACCACCAGGTCAGCCCATTCCGCCTG
GCCGACGCCTACCTGGAGGCGGCGCGCCAGAACGGCGTCGAGCTGTTGCTGGGAACCAACGTCACCGGCGTG
CTGCGCCAGGGCCGGCGGATCAGCGGAGTGCGCACGGACAATGCCGGGGTACTGCATTGCCGCACCCTGATC
AACGCCGCCGGCGCCTGGGCCGCCGAACTCAGCGAGCTGGCCACCGGCCGGCGCATCCCGGTGAAACCGGTG
AAGGGCCAGATCGTCCTCACCGAGCGTATGCCGCGACTGCTGAACGGTTGCCTGACCACCAGCGACTGCTAC
ATGGCGCAGAAGGACAACGGCGAGATCCTGATCGGCAGCACCACCGAGGACAAGGGCTTCGACGTCAGCAAC
ACCTTCCCGGAAATCGCCGGCCTGGTGCAGGGCGCGGTGCGTTGCGTGCCGGAGCTGCAACAGGTCAACCTC
AAGCGCACCTGGGCCGGCCTGCGCCCGGGCTCGCCGGACGAACTGCCGATTCTCGGTCCGGTGGCGGAGGTG
GAGGGCTACCTGAACGCCTGCGGGCATTTCCGCACCGGTATCCTCACCTCGGCGGTCACCGGGGTGCTGCTC
GACCGGCTGGTCCACGAAGAGACGCTGCCGCTGGACATCGCGCCGTTCCTCGCCGCGCGCTTCCAGCCGGAG
CCTGCCGCCGTGGCGGTCGCGGCCTGCTAG
Translation:
MNRTYDIVIAGGGVIGASCAYQLSRRGNLRIAVVDDKRPGNATRASAGGLWAIGESVGLGCGVIFFRMMSSR
NRREAQGAAVAVDASTPHILPPAFFDLALQSNALYPELHRELIERHGMDFKFERTGLKYVIQDDEDRQYAEH
IVAQIPHLAEQVRWLDREELRRAEPAVSHAAHGALEFLCDHQVSPFRLADAYLEAARQNGVELLLGTNVTGV
LRQGRRISGVRTDNAGVLHCRTLINAAGAWAAELSELATGRRIPVKPVKGQIVLTERMPRLLNGCLTTSDCY
MAQKDNGEILIGSTTEDKGFDVSNTFPEIAGLVQGAVRCVPELQQVNLKRTWAGLRPGSPDELPILGPVAEV
EGYLNACGHFRTGILTSAVTGVLLDRLVHEETLPLDIAPFLAARFQPEPAAVAVAAC*
AnnotationID:1348GeneID:1339
AnnotatorUID: diggins
Modification Date/Time: 2006-01-18 21:09:10
Gene Name:hcnC
Confidence Code:1
GeneProduct:hydrogen cyanide synthase HcnC
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(8) Central intermediary metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAC38596.1| (AF053760) hydrogen cyanide synthase HcnC [Pseudomonas fluorescens]
          Length = 417

 Score =  657 bits (1696), Expect = 0.0
 Identities = 324/417 (77%), Positives = 360/417 (86%), Gaps = 7/417 (1%)

>emb|CAD10849.1| (AJ418459) N-terminal hydrogen cyanide synthase [Pseudomonas sp.
           CA2]
          Length = 140

 Score =  237 bits (605), Expect = 9e-62
 Identities = 113/139 (81%), Positives = 128/139 (92%)






 
Structural Features:






   
Genomic Context:






   
Comment:


















    ReferenceID:2681




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19826




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:38245




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1339_cdd.html


    		




 
URL:

















    ReferenceID:38246




  
Author/Investigator(s):
        Pessi G, Haas D.





  
Title:
        Transcriptional control of the hydrogen cyanide biosynthetic genes hcnABC by the anaerobic regulator ANR and the quorum-sensing regulators LasR and RhlR in Pseudomonas aeruginosa.




  
PubMed:
        11092854


MedLine:
        




    
Source:
J Bacteriol. 2000 Dec;182(24):6940-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=11092854

















    ReferenceID:38247




  
Author/Investigator(s):
        Laville J, Blumer C, Von Schroetter C, Gaia V, Defago G, Keel C, Haas D.





  
Title:
        Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.




  
PubMed:
        9620970


MedLine:
        




    
Source:
J Bacteriol. 1998 Jun;180(12):3187-96.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=9620970

















    ReferenceID:38249




  
Author/Investigator(s):
        Gallagher LA, Manoil C.





  
Title:
        Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by cyanide poisoning.




  
PubMed:
        11591663


MedLine:
        




    
Source:
J Bacteriol. 2001 Nov;183(21):6207-14.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=11591663









           
Homologs By Global Alignment 

           

       



     
Gene ID:1339
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2446
                           PA2195_tr
                           translation of PA2195
                           417
                           99.28
                           99.76
                           0
                           2145.0
     

     
     
77785
                           gb|AAG05583.1|AE004646_4
                           (AE004646) hydrogen cyanide synthase HcnC [Pseudomonas aeruginosa PAO1]
                           417
                           99.28
                           99.76
                           0
                           2145.0
     

     
     
77786
                           gb|AAF21030.1|AF208523_3
                           (AF208523) hydrogen cyanide synthase HcnC [Pseudomonas aeruginosa]
                           417
                           99.28
                           99.76
                           0
                           2145.0
     

     
     
77787
                           gb|AAC38596.1|
                           (AF053760) hydrogen cyanide synthase HcnC [Pseudomonas fluorescens]
                           424
                           76.41
                           84.90
                           14
                           1701.0
     

     
     
77788
                           gb|AAQ59357.1|
                           (AE016916) hydrogen cyanide synthase HcnC [Chromobacterium violaceum ATCC 12472]
                           420
                           74.76
                           84.28
                           4
                           1643.0
     

     






      

          
GC ORFID: 44341How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2195Glimmer Score: 

          
Start: 1719244Stop: 1720497

          
Length: 1254


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA2195 translation of PA2195Homolog Bit Score 830.0

          
Other Homologs:  t_PA2195 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACAGAACCTATGACATCGTGATTGCCGGCGGCGGCGTGATCGGCGCGTCCTGCGCCTACCAACTGTCC 
AGGCGCGGCAACCTGCGCATCGCCGTGGTCGACGACAAGCGACCGGGCAACGCCACCCGCGCCTCGGCCGGC 
GGCCTCTGGGCCATCGGCGAATCGGTGGGGCTGGGCTGCGGGGTGATCTTCTTCCGCATGATGTCCTCCCGC 
AACCGGCGCGAGGCCCAGGGCGCGGCGGTGGCGGTGGACGCGAGCACGCCGCACATCCTGCCGCCGGCGTTC 
TTCGACCTCGCCCTGCAATCCAACGCGCTGTACCCGGAACTGCACCGAGAACTGATCGAACGCCACGGGATG 
GACTTCAAGTTCGAGCGCACCGGCCTGAAATACGTGATCCAGGACGACGAGGATCGCCAGTACGCCGAGCAC 
ATCGTGGCGCAGATCCCGCATCTGGCCGAGCAGGTACGCTGGCTGGACCGCGAGGAACTGCGTCGTGCCGAG 
CCGGCGGTCAGCCACGCGGCCCACGGCGCGCTGGAATTCCTCTGCGACCACCAGGTCAGCCCATTCCGCCTG 
GCCGACGCCTACCTGGAGGCGGCGCGCCAGAACGGCGTCGAGCTGTTGCTGGGAACCAACGTCACCGGCGTG 
CTGCGCCAGGGCCGGCGGATCAGCGGAGTGCGCACGGACAATGCCGGGGTACTGCATTGCCGCACCCTGATC 
AACGCCGCCGGCGCCTGGGCCGCCGAACTCAGCGAGCTGGCCACCGGCCGGCGCATCCCGGTGAAACCGGTG 
AAGGGCCAGATCGTCCTCACCGAGCGTATGCCGCGACTGCTGAACGGTTGCCTGACCACCAGCGACTGCTAC 
ATGGCGCAGAAGGACAACGGCGAGATCCTGATCGGCAGCACCACCGAGGACAAGGGCTTCGACGTCAGCAAC 
ACCTTCCCGGAAATCGCCGGCCTGGTGCAGGGCGCGGTGCGTTGCGTGCCGGAGCTGCAACAGGTCAACCTC 
AAGCGCACCTGGGCCGGCCTGCGCCCGGGCTCGCCGGACGAACTGCCGATTCTCGGTCCGGTGGCGGAGGTG 
GAGGGCTACCTGAACGCCTGCGGGCATTTCCGCACCGGTATCCTCACCTCGGCGGTCACCGGGGTGCTGCTC 
GACCGGCTGGTCCACGAAGAGACGCTGCCGCTGGACATCGCGCCGTTCCTCGCCGCGCGCTTCCAGCCGGAG 
CCTGCCGCCGTGGCGGTCGCGGCCTGCTAG