ViewGene
Locus Name:
GeneID:
Location:

GeneID:1306
TrivialName: PA14_23880
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23880
PAO1 Ortholog Locus:PA3111
Sequence Length:1290
Protein Length:429
Start: 2075598
Stop: 2076887
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06499.1|AE004735_6 (AE004735) folylpolyglutamate synthetase [Pseudomonas aeruginosa PAO1]
Identities = 424/429 (98%), Positives = 428/429 (99%)
Sequence:
ATGACCCAGCGTTCCCTGGCCGATTGGCTGAGCTATCTCGAACAACTCCATCCGACGGCCATCGACATGGGT
CTGGAGCGTTCCCGCGAGGTAGCGCGCCGGCTCGGCCTGGGAAGGCCGGCGAAACGCGTGGTCACCGTTACC
GGGACCAACGGCAAGGGCTCTACCTGCGCCCTGCTCGCCGAGCTGCTGCGTGAGCAGGGGTTGTCGGTCGGG
GTCTACAGCTCGCCGCACCTGCTGCGCTATAACGAGCGGGTGCGGATCGACGGCATCGAGGCCGGCGATGCG
CAACTGTGCGACGCCTTCTCCGCGGTGGAGGCCGCACGCGGCGAGATTTCCCTGACCTATTTCGAAATGGGC
ACGCTGGCCGCCTTCTGGCTGTTCGAGCGCGCCGGGCTGGACTTCGCGGTGCTGGAAGTCGGCCTTGGCGGG
CGCCTGGATGCGGTCAACCTGATCGACGCCGACCTGGCGCTGATCACCAGCATCGGCCTGGACCATGCCGAG
TGGCTGGGCGATACCCGCGAAAGCGTGGCTTTCGAGAAAGCCGGTATCCTGCGCGCCGGCAAACCGGCCCTG
TGCGGCGATCTCGATCCCCCGCAGCCATTGCTGGAGCAGGTGGCTGCGCTGGGGGCACCGCTTTACCTGCGC
GGTCGCGACTACGACCTGGCGCTCGCCGATTATGGCTGGCACTGGCGCGGGCTGGCCGCGGACGGCCAGGCG
CTGTCGCTGCACGATCTGCCGTTGCTCGAGTTGCCCATGGAAAACGCCGCGCTGGCCCTGCAGGCCTACGCG
TTGCTCGAGTTGCCCTGGCAGGCGGAGCGCCTGGCCGAGGCGCTGCGGCGGACCCGGGTGACCGGTCGCCTC
GATCGCCGCGACCTGTCCTGGGACGGCCAGCCACGCCAGCTCCTGCTGGACGTCGGGCACAATCCCCAGGCC
GCCCAGTACCTGGCGCAACGCCTGCGTGCCGCAGCGCCACGAGGACGCTACCTGGCGGTCTTCGGCCTGCTG
GCGGACAAAGACCTGGATGGCGTACTGGAACCCTTGACCGGCTTGGTGCAGGATTGGGCCGTTGCACCGTTG
CCGACCCCGCGTTCGCGGCCGGCCGCGGAGCTGGAGGCGGCGCTGATCCTGCGCCAGGTTCCGGCGAGCAGC
CATGCGGATATCGCCGCTGCCCTGGACGCGCAGTGCGCCAAGGCTACCGCGGATGATGTCATTCTGCTGTTC
GGATCGTTCTATAGCGTGGCCGAAGGCCTGGAGTGGCTGGCCCGTAGAACGGATAAGGGGGAGTAA
Translation:
MTQRSLADWLSYLEQLHPTAIDMGLERSREVARRLGLGRPAKRVVTVTGTNGKGSTCALLAELLREQGLSVG
VYSSPHLLRYNERVRIDGIEAGDAQLCDAFSAVEAARGEISLTYFEMGTLAAFWLFERAGLDFAVLEVGLGG
RLDAVNLIDADLALITSIGLDHAEWLGDTRESVAFEKAGILRAGKPALCGDLDPPQPLLEQVAALGAPLYLR
GRDYDLALADYGWHWRGLAADGQALSLHDLPLLELPMENAALALQAYALLELPWQAERLAEALRRTRVTGRL
DRRDLSWDGQPRQLLLDVGHNPQAAQYLAQRLRAAAPRGRYLAVFGLLADKDLDGVLEPLTGLVQDWAVAPL
PTPRSRPAAELEAALILRQVPASSHADIAAALDAQCAKATADDVILLFGSFYSVAEGLEWLARRTDKGE*
AnnotationID:1315GeneID:1306
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 07:07:10
Gene Name:folC
Confidence Code:1
GeneProduct: folylpolyglutamate synthetase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name: dihydrofolate synthetase
Functional Category Confidence Code:5
COGs:COG0285
Secondary Functional Category(ies):
EC Number:6.3.2.17
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67611.1|AE016391_2 (AE016781) folylpolyglutamate synthetase [Pseudomonas putida
           KT2440]
          Length = 436

 Score =  596 bits (1537), Expect = e-170
 Identities = 297/428 (69%), Positives = 348/428 (81%)

>gb|AAM40260.1| (AE012193) folylpolyglutamate synthase/dihydrofolate synthase
           [Xanthomonas campestris pv. campestris str. ATCC 33913]
          Length = 422

 Score =  383 bits (984), Expect = e-105
 Identities = 215/424 (50%), Positives = 281/424 (66%), Gaps = 12/424 (2%)

>gb|AAC75375.1| (AE000320) dihydrofolate:folylpolyglutamate synthetase;
           dihydrofolate synthetase [Escherichia coli K12]
          Length = 422

 Score =  338 bits (866), Expect = 5e-92
 Identities = 194/424 (45%), Positives = 257/424 (60%), Gaps = 14/424 (3%)






 
Structural Features:
COG0285, FolC, Folylpolyglutamate synthase 
[Coenzyme metabolism]
CD-Length = 427 residues,  99.8% aligned
Score =  412 bits (1060), Expect = 4e-116
Identities = 198/437 (45%), Positives = 257/437 (58%), Gaps = 21/437 (4%)






   
Genomic Context:






   
Comment:


















    ReferenceID:2615




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19757




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33481




  
Author/Investigator(s):
        Murata T, Bognar AL, Hayashi T, Ohnishi M, Nakayama K, Terawaki Y.





  
Title:
        Molecular analysis of the folC gene of Pseudomonas aeruginosa.




  
PubMed:
        11145267


MedLine:
        




    
Source:
Microbiol Immunol. 2000;44(11):879-86.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11145267

















    ReferenceID:38094




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1306_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1306
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2369
                           PA3111_tr
                           translation of PA3111
                           429
                           98.83
                           99.76
                           0
                           2166.0
     

     
     
75997
                           gb|AAG06499.1|AE004735_6
                           (AE004735) folylpolyglutamate synthetase [Pseudomonas aeruginosa PAO1]
                           429
                           98.83
                           99.76
                           0
                           2166.0
     

     
     
75998
                           dbj|BAB13796.1|
                           (AB031231) folylpolyglutamate synthetase [Pseudomonas aeruginosa]
                           429
                           98.83
                           99.76
                           0
                           2166.0
     

     
     
75999
                           gb|AAN67611.1|AE016391_2
                           (AE016781) folylpolyglutamate synthetase [Pseudomonas putida KT2440]
                           436
                           68.11
                           79.81
                           7
                           1535.0
     

     
     
76000
                           gb|AAO57283.1|
                           (AE016869) folylpolyglutamate synthase/dihydrofolate synthase [Pseudomonas syringae pv. tomato str. DC3000]
                           435
                           65.74
                           77.93
                           7
                           1467.0
     

     






      

          
GC ORFID: 44308How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3111Glimmer Score: 

          
Start: 2878333Stop: 2877044

          
Length: 1290


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA3111 translation of PA3111Homolog Bit Score 838.0

          
Other Homologs:  psyr_15may02_Scaffold7_revised_gene7131 (ORF: BLASTX 576.0), t_PA3111 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCCAGCGTTCCCTGGCCGATTGGCTGAGCTATCTCGAACAACTCCATCCGACGGCCATCGACATGGGT 
CTGGAGCGTTCCCGCGAGGTAGCGCGCCGGCTCGGCCTGGGAAGGCCGGCGAAACGCGTGGTCACCGTTACC 
GGGACCAACGGCAAGGGCTCTACCTGCGCCCTGCTCGCCGAGCTGCTGCGTGAGCAGGGGTTGTCGGTCGGG 
GTCTACAGCTCGCCGCACCTGCTGCGCTATAACGAGCGGGTGCGGATCGACGGCATCGAGGCCGGCGATGCG 
CAACTGTGCGACGCCTTCTCCGCGGTGGAGGCCGCACGCGGCGAGATTTCCCTGACCTATTTCGAAATGGGC 
ACGCTGGCCGCCTTCTGGCTGTTCGAGCGCGCCGGGCTGGACTTCGCGGTGCTGGAAGTCGGCCTTGGCGGG 
CGCCTGGATGCGGTCAACCTGATCGACGCCGACCTGGCGCTGATCACCAGCATCGGCCTGGACCATGCCGAG 
TGGCTGGGCGATACCCGCGAAAGCGTGGCTTTCGAGAAAGCCGGTATCCTGCGCGCCGGCAAACCGGCCCTG 
TGCGGCGATCTCGATCCCCCGCAGCCATTGCTGGAGCAGGTGGCTGCGCTGGGGGCACCGCTTTACCTGCGC 
GGTCGCGACTACGACCTGGCGCTCGCCGATTATGGCTGGCACTGGCGCGGGCTGGCCGCGGACGGCCAGGCG 
CTGTCGCTGCACGATCTGCCGTTGCTCGAGTTGCCCATGGAAAACGCCGCGCTGGCCCTGCAGGCCTACGCG 
TTGCTCGAGTTGCCCTGGCAGGCGGAGCGCCTGGCCGAGGCGCTGCGGCGGACCCGGGTGACCGGTCGCCTC 
GATCGCCGCGACCTGTCCTGGGACGGCCAGCCACGCCAGCTCCTGCTGGACGTCGGGCACAATCCCCAGGCC 
GCCCAGTACCTGGCGCAACGCCTGCGTGCCGCAGCGCCACGAGGACGCTACCTGGCGGTCTTCGGCCTGCTG 
GCGGACAAAGACCTGGATGGCGTACTGGAACCCTTGACCGGCTTGGTGCAGGATTGGGCCGTTGCACCGTTG 
CCGACCCCGCGTTCGCGGCCGGCCGCGGAGCTGGAGGCGGCGCTGATCCTGCGCCAGGTTCCGGCGAGCAGC 
CATGCGGATATCGCCGCTGCCCTGGACGCGCAGTGCGCCAAGGCTACCGCGGATGATGTCATTCTGCTGTTC 
GGATCGTTCTATAGCGTGGCCGAAGGCCTGGAGTGGCTGGCCCGTAGAACGGATAAGGGGGAGTAA