ViewGene
Locus Name:
GeneID:
Location:

GeneID:1284
TrivialName: PA14_16070
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_16070
PAO1 Ortholog Locus:PA3736
Sequence Length:1305
Protein Length:434
Start: 1368457
Stop: 1369761
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07123.1|AE004792_8 (AE004792) homoserine dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 433/434 (99%), Positives = 434/434 (100%)
Sequence:
GTGAAACCGGTCAAAGTAGGCATCTGTGGGTTGGGGACCGTCGGTGGCGGTACCTTCAATGTACTCAAACGC
AACGCCGAGGAGATTGCCCGCCGTGCCGGGCGCGGTATCGAGGTTGCGCAGATCGCCGCCCGCCGGCCGAAC
CCGAAGTGCGATACCGGTGCGACCCCCATCACCGCCGATATCTTCGACGTAGCGTGCAATCCCGAGATCGAC
GTGGTCGTCGAGTTGATCGGCGGCTACACCCTGGCCCACGAGCTGGTGCTCAAGGCCATCGAGAACGGCAAG
CACGTGGTCACCGCGAACAAGGCGCTGATCGCCGTGCACGGCAACGAGATCTTCGCCAAGGCCCGCGAGAAG
GGCGTGATCGTCGCCTTCGAGGCCGCTGTCGCCGGCGGCATCCCGGTGATCAAGGCGATCCGCGAGGGGCTG
TCGGCTAACCGCATCAACTGGCTGGCCGGGATCATCAACGGTACCGGCAACTTCATCCTCAGCGAAATGCGC
GAGAAGGGCCGTACCTTCCCCGACGTGCTCGCCGAGGCCCAGGCCCTGGGCTATGCCGAGGCCGACCCGACC
TTCGACGTGGAAGGCATCGACGCCGCCCACAAGCTGACCATCCTCGCCTCGATCGCCTTCGGCATTCCGCTG
CAGTTCGACAAGGCCTACACCGAAGGCATCTCGAAACTGACCAGCGCCGACGTCAACTACGCCGACGCCCTC
GGCTATCGCATCAAGCACCTGGGCGTGGCGCGTCGCACCGAGAGCGGCTTCGAGCTGCGCGTGCACCCGACC
CTGATTCCCTCGGATCGCCTGATCGCCAACGTCAACGGCGTGATGAACGCGGTGATGGTCAACGGCGACGCC
GTCGGCTCGACCCTCTACTACGGCGCCGGTGCCGGCATGGAGCCGACCGCTTCCTCGGTGGTGGCCGACCTC
GTCGACGTGGTCCGCGCCATGACCTCCGATCCGGAGAACCGCGTACCGCACCTGGCATTCCAGCCGGACGCG
CTGTCCGACCACCCGATCCTGCCGATCGAAGCCTGCGAAAGCGCCTACTACCTGCGCATCCAGGCCAAAGAC
CACCCGGGCGTACTGGCCCAGGTGGCCACCATCCTGTCCGAGCGCGGCATCAACATCGAATCGATCATGCAG
AAGGAGGCCGAGGAACAGGACGGCCTGGTGCCGATGATCCTGGTTACCCACCGGGTCATCGAACAACGCATC
AACGATGCCATCGCCGCCCTGGAAGCGCTGGAAGGCGTGTCCGGGCCGGTGGTCCGTATCCGTGTCGAACAA
CTGAATTGA
Translation:
MKPVKVGICGLGTVGGGTFNVLKRNAEEIARRAGRGIEVAQIAARRPNPKCDTGATPITADIFDVACNPEID
VVVELIGGYTLAHELVLKAIENGKHVVTANKALIAVHGNEIFAKAREKGVIVAFEAAVAGGIPVIKAIREGL
SANRINWLAGIINGTGNFILSEMREKGRTFPDVLAEAQALGYAEADPTFDVEGIDAAHKLTILASIAFGIPL
QFDKAYTEGISKLTSADVNYADALGYRIKHLGVARRTESGFELRVHPTLIPSDRLIANVNGVMNAVMVNGDA
VGSTLYYGAGAGMEPTASSVVADLVDVVRAMTSDPENRVPHLAFQPDALSDHPILPIEACESAYYLRIQAKD
HPGVLAQVATILSERGINIESIMQKEAEEQDGLVPMILVTHRVIEQRINDAIAALEALEGVSGPVVRIRVEQ
LN*
AnnotationID:1293GeneID:1284
AnnotatorUID: diggins
Modification Date/Time: 2005-04-22 08:08:10
Gene Name:hom
Confidence Code:1
GeneProduct:homoserine dehydrogenase
Cell Localization:()
Synonyms:metL
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0460,pfam00742,pfam03447
Secondary Functional Category(ies):
EC Number:1.1.1.3
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO55001.1| (AE016861) homoserine dehydrogenase [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 434

 Score =  776 bits (2004), Expect = 0.0
 Identities = 395/434 (91%), Positives = 412/434 (94%)

>emb|CAE37774.1| (BX640430) homoserine dehydrogenase [Bordetella parapertussis]
          Length = 434

 Score =  530 bits (1364), Expect = e-150
 Identities = 278/436 (63%), Positives = 337/436 (77%), Gaps = 6/436 (1%)






 
Structural Features:
COG0460, ThrA, Homoserine dehydrogenase 
[Amino acid transport and metabolism]
CD-Length = 333 residues, 100.0% aligned
Score =  369 bits (950), Expect = 3e-103
Identities = 163/333 (48%), Positives = 211/333 (63%), Gaps = 11/333 (3%)

pfam00742, Homoserine_dh, Homoserine dehydrogenase.
CD-Length = 185 residues, 100.0% aligned
Score =  243 bits (621), Expect = 3e-65
Identities = 108/185 (58%), Positives = 124/185 (67%), Gaps = 6/185 (3%)

pfam03447, NAD_binding_3, Homoserine dehydrogenase, NAD binding domain.
CD-Length = 132 residues, 100.0% aligned
Score =  141 bits (358), Expect = 1e-34
Identities = 60/133 (45%), Positives = 73/133 (54%), Gaps = 3/133 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14321




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19713




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31821




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1284_cdd.html


    		




 
URL:

















    ReferenceID:34256




  
Author/Investigator(s):
        Clepet C, Borne F, Krishnapillai V, Baird C, Patte JC, Cami B.





  
Title:
        Isolation, organization and expression of the Pseudomonas aeruginosa threonine genes.




  
PubMed:
        1333566


MedLine:
        




    
Source:
Mol Microbiol. 1992 Nov;6(21):3109-19.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1333566









           
Homologs By Global Alignment 

           

       



     
Gene ID:1284
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2342
                           PA3736_tr
                           translation of PA3736
                           434
                           99.76
                           99.99
                           0
                           2178.0
     

     
     
75243
                           gb|AAG07123.1|AE004792_8
                           (AE004792) homoserine dehydrogenase [Pseudomonas aeruginosa PAO1]
                           434
                           99.53
                           99.99
                           0
                           2175.0
     

     
     
75244
                           gb|AAO55001.1|
                           (AE016861) homoserine dehydrogenase [Pseudomonas syringae pv. tomato str. DC3000]
                           434
                           90.78
                           94.93
                           0
                           2000.0
     

     
     
75245
                           gb|AAN67092.1|AE016338_2
                           (AE016779) homoserine dehydrogenase [Pseudomonas putida KT2440]
                           434
                           90.78
                           94.93
                           0
                           1997.0
     

     
     
75246
                           emb|CAA46167.1|
                           (X65033) homoserine dehydrogenase [Pseudomonas aeruginosa]
                           443
                           86.90
                           88.03
                           13
                           1854.0
     

     






      

          
GC ORFID: 44286How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3736Glimmer Score: 

          
Start: 3585480Stop: 3584176

          
Length: 1305


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3736 translation of PA3736Homolog Bit Score 843.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4568 (ORF: BLASTX 775.0), t_PA3736 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGAAACCGGTCAAAGTAGGCATCTGTGGGTTGGGGACCGTCGGTGGCGGTACCTTCAATGTACTCAAACGC 
AACGCCGAGGAGATTGCCCGCCGTGCCGGGCGCGGTATCGAGGTTGCGCAGATCGCCGCCCGCCGGCCGAAC 
CCGAAGTGCGATACCGGTGCGACCCCCATCACCGCCGATATCTTCGACGTAGCGTGCAATCCCGAGATCGAC 
GTGGTCGTCGAGTTGATCGGCGGCTACACCCTGGCCCACGAGCTGGTGCTCAAGGCCATCGAGAACGGCAAG 
CACGTGGTCACCGCGAACAAGGCGCTGATCGCCGTGCACGGCAACGAGATCTTCGCCAAGGCCCGCGAGAAG 
GGCGTGATCGTCGCCTTCGAGGCCGCTGTCGCCGGCGGCATCCCGGTGATCAAGGCGATCCGCGAGGGGCTG 
TCGGCTAACCGCATCAACTGGCTGGCCGGGATCATCAACGGTACCGGCAACTTCATCCTCAGCGAAATGCGC 
GAGAAGGGCCGTACCTTCCCCGACGTGCTCGCCGAGGCCCAGGCCCTGGGCTATGCCGAGGCCGACCCGACC 
TTCGACGTGGAAGGCATCGACGCCGCCCACAAGCTGACCATCCTCGCCTCGATCGCCTTCGGCATTCCGCTG 
CAGTTCGACAAGGCCTACACCGAAGGCATCTCGAAACTGACCAGCGCCGACGTCAACTACGCCGACGCCCTC 
GGCTATCGCATCAAGCACCTGGGCGTGGCGCGTCGCACCGAGAGCGGCTTCGAGCTGCGCGTGCACCCGACC 
CTGATTCCCTCGGATCGCCTGATCGCCAACGTCAACGGCGTGATGAACGCGGTGATGGTCAACGGCGACGCC 
GTCGGCTCGACCCTCTACTACGGCGCCGGTGCCGGCATGGAGCCGACCGCTTCCTCGGTGGTGGCCGACCTC 
GTCGACGTGGTCCGCGCCATGACCTCCGATCCGGAGAACCGCGTACCGCACCTGGCATTCCAGCCGGACGCG 
CTGTCCGACCACCCGATCCTGCCGATCGAAGCCTGCGAAAGCGCCTACTACCTGCGCATCCAGGCCAAAGAC 
CACCCGGGCGTACTGGCCCAGGTGGCCACCATCCTGTCCGAGCGCGGCATCAACATCGAATCGATCATGCAG 
AAGGAGGCCGAGGAACAGGACGGCCTGGTGCCGATGATCCTGGTTACCCACCGGGTCATCGAACAACGCATC 
AACGATGCCATCGCCGCCCTGGAAGCGCTGGAAGGCGTGTCCGGGCCGGTGGTCCGTATCCGTGTCGAACAA 
CTGAATTGA