ViewGene
Locus Name:
GeneID:
Location:

GeneID:1247
TrivialName: PA14_12390
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_12390
PAO1 Ortholog Locus:PA3977
Sequence Length:1284
Protein Length:427
Start: 1067594
Stop: 1066311
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07364.1|AE004815_8 (AE004815) glutamate-1-semialdehyde 2,1-aminomutase [Pseudomonas aeruginosa PAO1]
Identities = 426/427 (99%), Positives = 427/427 (100%)
Sequence:
ATGTCCCGTTCCGAAACGCTGTTCAACAACGCCCAGAAACACATTCCCGGCGGGGTCAACTCCCCGGTGCGC
GCCTTCAAGAGCGTCGGCGGCACCCCGCTGTTCTTCAAGCACGCCGAAGGCGCCTATGTACTGGACGAGGAC
GACAAGCGCTACGTGGACTATGTCGGCTCCTGGGGCCCGATGATCCTCGGCCACAGCCATCCGGACGTGCTC
GACGCGGTGCGCCGGCAGCTCGACCACGGCCTGTCCTATGGCGCGCCGACCGCGCTGGAAGTGGAAATGGCC
GACCTGGTCTGCTCCATGGTGCCGTCGATGGAGATGGTGCGCATGGTCAGCTCCGGCACCGAGGCGACCATG
AGCGCCATCCGCCTGGCCCGCGGCTACACCGGGCGCGACAGCATCATCAAGTTCGAAGGCTGCTACCACGGC
CACTCCGACAGCCTGCTGGTGAAGGCCGGCTCCGGCGCGTTGACCTTCGGCGTGCCGAACTCCCCGGGCGTT
CCGGCAGCCTTCGCCAAGCACACCCTGACCCTGCCGTTCAACGACATCGAGGCGGTGCGCAAGACACTGGGC
GAAGTCGGCAAGGAGGTCGCCTGCATCATCGTCGAGCCGGTTGCCGGCAACATGAACTGTGTGCCGCCGGCG
CCGGGCTTCCTCGAAGGCCTGCGTGAAGCCTGCGACGAACACGGCGTGGTGCTGATCTTCGACGAAGTGATG
ACCGGCTTCCGTGTCGCCCTCGGCGGCGCCCAGGCCTACTACGGGGTCACCCCGGACCTGTCGACCTTCGGC
AAGATCATCGGCGGCGGCATGCCGGTGGGCGCCTTCGGCGGCAAGCGCGAGATCATGCAGCAGATTTCCCCG
CTGGGCCCGGTCTACCAGGCCGGCACGCTCTCGGGCAACCCGCTGGCAATGGCCGCCGGCCTGACCACCCTG
CGCCTGATCAGCCGCCCCGGTTTCCACAACGAACTGACCGCCTACACCACGCGCATGCTCGACGGCCTGCAA
CAGCGCGCGGATGCCGCCGGCATCCCCTTCGTCACCACCCAGGCGGGCGGCATGTTCGGCCTGTACTTCAGC
GGCGCCGACGCCATCGTCACCTTCGAGGACGTGATGGCCAGCGACGTCGAACGCTTCAAGCGCTTCTTCCAC
CTGATGCTTGACGGTGGCGTGTACCTTGCGCCTAGCGCCTTCGAGGCCGGCTTCACCTCCATCGCCCATGGC
GACAAGGAGCTGGAAATCACGCTGAACGCCGCCGAAAAAGCCTTCGCCGCGCTGAAATGA
Translation:
MSRSETLFNNAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVLDEDDKRYVDYVGSWGPMILGHSHPDVL
DAVRRQLDHGLSYGAPTALEVEMADLVCSMVPSMEMVRMVSSGTEATMSAIRLARGYTGRDSIIKFEGCYHG
HSDSLLVKAGSGALTFGVPNSPGVPAAFAKHTLTLPFNDIEAVRKTLGEVGKEVACIIVEPVAGNMNCVPPA
PGFLEGLREACDEHGVVLIFDEVMTGFRVALGGAQAYYGVTPDLSTFGKIIGGGMPVGAFGGKREIMQQISP
LGPVYQAGTLSGNPLAMAAGLTTLRLISRPGFHNELTAYTTRMLDGLQQRADAAGIPFVTTQAGGMFGLYFS
GADAIVTFEDVMASDVERFKRFFHLMLDGGVYLAPSAFEAGFTSIAHGDKELEITLNAAEKAFAALK*
AnnotationID:1256GeneID:1247
AnnotatorUID: urbach
Modification Date/Time: 2004-08-30 15:03:28
Gene Name:hemL
Confidence Code:1
GeneProduct:glutamate 1-semialdehyde 2,1-aminomutase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:synthesis of 5-aminolevulinic acid (ALA)
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0001, KOG1401, pfam00202
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:
biosynthesis of tetrapyrroles (porphyrine biosynthesis)
Homology:
gnl|CDD|9877 COG0001, HemL, Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]
Length = 432
Score =  631 bits (1628), Expect = 0.0
 Identities = 271/428 (63%), Positives = 330/428 (77%), Gaps = 2/428 (0%)
Structural Features:






   
Genomic Context:






   
Comment:


















    ReferenceID:2497




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19640




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34079




  
Author/Investigator(s):
        Hungerer C, Troup B, Romling U, Jahn D.





  
Title:
        Cloning, mapping and characterization of the Pseudomonas aeruginosa hemL gene.




  
PubMed:
        7565600


MedLine:
        96004705




    
Source:
Mol Gen Genet. 1995 Aug 21;248(3):375-80.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00557262&dopt=GenPept









           
Homologs By Global Alignment 

           

       



     
Gene ID:1247
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2265
                           PA3977_tr
                           translation of PA3977
                           427
                           99.76
                           99.99
                           0
                           2208.0
     

     
     
74130
                           gb|AAG07364.1|AE004815_8
                           (AE004815) glutamate-1-semialdehyde 2,1-aminomutase [Pseudomonas aeruginosa PAO1]
                           427
                           99.76
                           99.99
                           0
                           2208.0
     

     
     
74131
                           emb|CAA57575.1|
                           (X82072) glutamate 1-semialdehyde 2,1-aminomutase [Pseudomonas aeruginosa]
                           427
                           99.53
                           99.99
                           0
                           2205.0
     

     
     
74132
                           gb|AAN70353.1|AE016677_4
                           (AE016792) glutamate-1-semialdehyde-2,1-aminomutase [Pseudomonas putida KT2440]
                           427
                           89.92
                           94.37
                           0
                           2010.0
     

     
     
74133
                           gb|AAO58229.1|
                           (AE016873) glutamate-1-semialdehyde-2,1-aminomutase [Pseudomonas syringae pv. tomato str. DC3000]
                           427
                           89.22
                           93.67
                           0
                           1995.0
     

     






      

          
GC ORFID: 44249How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3977Glimmer Score: 

          
Start: 3886344Stop: 3887627

          
Length: 1284


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3977 translation of PA3977Homolog Bit Score 855.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5724 (ORF: BLASTX 783.0), t_PA3977 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCCGTTCCGAAACGCTGTTCAACAACGCCCAGAAACACATTCCCGGCGGGGTCAACTCCCCGGTGCGC 
GCCTTCAAGAGCGTCGGCGGCACCCCGCTGTTCTTCAAGCACGCCGAAGGCGCCTATGTACTGGACGAGGAC 
GACAAGCGCTACGTGGACTATGTCGGCTCCTGGGGCCCGATGATCCTCGGCCACAGCCATCCGGACGTGCTC 
GACGCGGTGCGCCGGCAGCTCGACCACGGCCTGTCCTATGGCGCGCCGACCGCGCTGGAAGTGGAAATGGCC 
GACCTGGTCTGCTCCATGGTGCCGTCGATGGAGATGGTGCGCATGGTCAGCTCCGGCACCGAGGCGACCATG 
AGCGCCATCCGCCTGGCCCGCGGCTACACCGGGCGCGACAGCATCATCAAGTTCGAAGGCTGCTACCACGGC 
CACTCCGACAGCCTGCTGGTGAAGGCCGGCTCCGGCGCGTTGACCTTCGGCGTGCCGAACTCCCCGGGCGTT 
CCGGCAGCCTTCGCCAAGCACACCCTGACCCTGCCGTTCAACGACATCGAGGCGGTGCGCAAGACACTGGGC 
GAAGTCGGCAAGGAGGTCGCCTGCATCATCGTCGAGCCGGTTGCCGGCAACATGAACTGTGTGCCGCCGGCG 
CCGGGCTTCCTCGAAGGCCTGCGTGAAGCCTGCGACGAACACGGCGTGGTGCTGATCTTCGACGAAGTGATG 
ACCGGCTTCCGTGTCGCCCTCGGCGGCGCCCAGGCCTACTACGGGGTCACCCCGGACCTGTCGACCTTCGGC 
AAGATCATCGGCGGCGGCATGCCGGTGGGCGCCTTCGGCGGCAAGCGCGAGATCATGCAGCAGATTTCCCCG 
CTGGGCCCGGTCTACCAGGCCGGCACGCTCTCGGGCAACCCGCTGGCAATGGCCGCCGGCCTGACCACCCTG 
CGCCTGATCAGCCGCCCCGGTTTCCACAACGAACTGACCGCCTACACCACGCGCATGCTCGACGGCCTGCAA 
CAGCGCGCGGATGCCGCCGGCATCCCCTTCGTCACCACCCAGGCGGGCGGCATGTTCGGCCTGTACTTCAGC 
GGCGCCGACGCCATCGTCACCTTCGAGGACGTGATGGCCAGCGACGTCGAACGCTTCAAGCGCTTCTTCCAC 
CTGATGCTTGACGGTGGCGTGTACCTTGCGCCTAGCGCCTTCGAGGCCGGCTTCACCTCCATCGCCCATGGC 
GACAAGGAGCTGGAAATCACGCTGAACGCCGCCGAAAAAGCCTTCGCCGCGCTGAAATGA