ViewGene
Locus Name:
GeneID:
Location:

GeneID:1194
TrivialName: PA14_18580
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_18580
PAO1 Ortholog Locus:PA3540
Sequence Length:1311
Protein Length:436
Start: 1595308
Stop: 1593998
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06928.1|AE004774_6 (AE004774) GDP-mannose 6-dehydrogenase AlgD [Pseudomonas aeruginosa PAO1]
Identities = 436/436 (100%), Positives = 436/436 (100%)
Sequence:
ATGCGAATCAGCATCTTTGGTTTGGGCTATGTCGGTGCAGTATGTGCTGGCTGCCTGTCGGCACGCGGTCAT
GAAGTCATTGGTGTGGATGTCTCCAGCACCAAGATCGACCTGATCAACCAGGGCAAGTCGCCCATCGTCGAA
CCGGGCCTGGAAGCGTTGTTGCAGCAAGGCCGGCAGACCGGACGGCTGTCGGGCACCACCGATTTCAAGAAG
GCCGTGCTGGACTCCGACGTATCGTTCATCTGCGTCGGCACGCCGAGCAAGAAGAACGGCGACCTGGACCTG
GGCTACATCGAGACCGTCTGCCGCGAGATCGGCTTCGCCATCCGCGAGAAGTCCGAACGCCACACCGTGGTG
GTGCGCAGCACCGTACTGCCGGGCACCGTCAACAACGTGGTGATCCCGCTGATCGAGGACTGCTCGGGCAAG
AAGGCCGGGGTCGACTTCGGCGTCGGCACCAACCCCGAATTCCTCCGCGAGAGCACCGCGATCAAGGACTAC
GACTTCCCGCCGATGACCGTGATCGGCGAACTGGACAAGCAGACCGGCGACCTTCTCGAGGAAATCTACCGC
GAGCTGGACGCGCCGATCATCCGCAAGACCGTCGAGGTCGCCGAGATGATCAAGTACACCTGCAACGTCTGG
CACGCCGCCAAGGTCACCTTCGCCAACGAGATCGGCAACATCGCCAAGGCGGTCGGCGTCGACGGCCGCGAG
GTGATGGACGTGATCTGCCAGGACCACAAGCTCAACCTGTCGCGCTACTACATGCGTCCCGGCTTCGCCTTC
GGCGGCTCCTGCCTGCCCAAGGATGTACGCGCCCTCACCTATCGCGCCAGCCAGCTGGACGTCGAGCACCCG
ATGCTCGGTTCGTTGATGCGCAGCAACTCCAACCAGGTGCAGAAGGCCTTCGATCTCATCACCAGCCACGAC
ACCCGCAAGGTCGGCCTGCTCGGCCTGTCGTTCAAGGCCGGCACCGACGATTTGCGCGAAAGCCCGCTGGTG
GAGCTGGCCGAGATGCTCATCGGCAAGGGCTACGAGTTGCGCATCTTCGACCGCAACGTCGAATACGCGCGT
GTCCACGGGGCCAACAAGGAATACATCGAGTCGAAGATCCCGCACGTCTCCTCACTGCTGGTCTCCGACCTC
GACGAAGTGGTGGCGAGTTCCGATGTGCTGGTGCTGGGCAATGGCGACGAGCTGTTCGTCGACCTGGTGAAC
AAGACCCCGAGCGGCAAGAAGCTGGTCGACCTGGTGGGCTTCATGCCGCACACCACCACTGCCCAGGCCGAG
GGCATCTGCTGGTAG
Translation:
MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQTGRLSGTTDFKK
AVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVVVRSTVLPGTVNNVVIPLIEDCSGK
KAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELDKQTGDLLEEIYRELDAPIIRKTVEVAEMIKYTCNVW
HAAKVTFANEIGNIAKAVGVDGREVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHP
MLGSLMRSNSNQVQKAFDLITSHDTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNVEYAR
VHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVDLVGFMPHTTTAQAE
GICW*
AnnotationID:1203GeneID:1194
AnnotatorUID: danlee
Modification Date/Time: 2006-03-11 16:04:25
Gene Name:algD
Confidence Code:1
GeneProduct:GDP-mannose 6-dehydrogenase AlgD
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(23) Secreted Factors (toxins, enzymes, alginate)
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam03721,COG1004
Secondary Functional Category(ies):Adaptation, protection; Cell wall / LPS / capsule
EC Number:1.1.1.132
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAB58939.1| (AF001555) GDP mannose dehydrogenase [Pseudomonas syringae pv.
           phaseolicola]
          Length = 438

 Score =  710 bits (1832), Expect = 0.0
 Identities = 346/438 (78%), Positives = 390/438 (89%), Gaps = 2/438 (0%)

>gb|AAN66912.1|AE016319_8 (AE016778) GDP-mannose 6-dehydrogenase [Pseudomonas putida KT2440]
          Length = 438

 Score =  698 bits (1802), Expect = 0.0
 Identities = 345/438 (78%), Positives = 387/438 (88%), Gaps = 2/438 (0%)









 
Structural Features:
pfam03721, UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase family
CD-Length = 192 residues, 100.0% aligned
Score =  233 bits (595), Expect = 4e-62
Identities = 98/196 (50%), Positives = 124/196 (63%), Gaps = 4/196 (2%)

COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase 
[Cell envelope biogenesis, outer membrane]
CD-Length = 414 residues, 100.0% aligned
Score =  446 bits (1150), Expect = 2e-126
Identities = 155/434 (35%), Positives = 238/434 (54%), Gaps = 28/434 (6%)






   
Genomic Context:






   
Comment:


















    ReferenceID:2391




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19533




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32024




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1194_cdd.html


    		




 
URL:

















    ReferenceID:34126




  
Author/Investigator(s):
        Deretic V, Gill JF, Chakrabarty AM.





  
Title:
        Pseudomonas aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional regulation of the algD gene.




  
PubMed:
        3108855


MedLine:
        




    
Source:
Nucleic Acids Res. 1987 Jun 11;15(11):4567-81.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=3108855









           
Homologs By Global Alignment 

           

       



     
Gene ID:1194
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2151
                           PA3540_tr
                           translation of PA3540
                           436
                           99.99
                           99.99
                           0
                           2240.0
     

     
     
71852
                           gb|AAG06928.1|AE004774_6
                           (AE004774) GDP-mannose 6-dehydrogenase AlgD [Pseudomonas aeruginosa PAO1]
                           436
                           99.99
                           99.99
                           0
                           2240.0
     

     
     
71853
                           emb|CAA68425.1|
                           (Y00337) unnamed protein product [Pseudomonas aeruginosa]
                           436
                           99.77
                           99.77
                           0
                           2236.0
     

     
     
71854
                           gb|AAB58939.1|
                           (AF001555) GDP mannose dehydrogenase [Pseudomonas syringae pv. phaseolicola] [Pseudomonas savastanoi pv. phaseolicola]
                           438
                           78.99
                           89.04
                           2
                           1834.0
     

     
     
71858
                           gb|AAN66912.1|AE016319_8
                           (AE016778) GDP-mannose 6-dehydrogenase [Pseudomonas putida KT2440]
                           438
                           78.76
                           88.35
                           2
                           1804.0
     

     






      

          
GC ORFID: 44196How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3540Glimmer Score: 

          
Start: 3358626Stop: 3359936

          
Length: 1311


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA3540 translation of PA3540Homolog Bit Score 867.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4991 (ORF: BLASTX 710.0), t_PA3540 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGAATCAGCATCTTTGGTTTGGGCTATGTCGGTGCAGTATGTGCTGGCTGCCTGTCGGCACGCGGTCAT 
GAAGTCATTGGTGTGGATGTCTCCAGCACCAAGATCGACCTGATCAACCAGGGCAAGTCGCCCATCGTCGAA 
CCGGGCCTGGAAGCGTTGTTGCAGCAAGGCCGGCAGACCGGACGGCTGTCGGGCACCACCGATTTCAAGAAG 
GCCGTGCTGGACTCCGACGTATCGTTCATCTGCGTCGGCACGCCGAGCAAGAAGAACGGCGACCTGGACCTG 
GGCTACATCGAGACCGTCTGCCGCGAGATCGGCTTCGCCATCCGCGAGAAGTCCGAACGCCACACCGTGGTG 
GTGCGCAGCACCGTACTGCCGGGCACCGTCAACAACGTGGTGATCCCGCTGATCGAGGACTGCTCGGGCAAG 
AAGGCCGGGGTCGACTTCGGCGTCGGCACCAACCCCGAATTCCTCCGCGAGAGCACCGCGATCAAGGACTAC 
GACTTCCCGCCGATGACCGTGATCGGCGAACTGGACAAGCAGACCGGCGACCTTCTCGAGGAAATCTACCGC 
GAGCTGGACGCGCCGATCATCCGCAAGACCGTCGAGGTCGCCGAGATGATCAAGTACACCTGCAACGTCTGG 
CACGCCGCCAAGGTCACCTTCGCCAACGAGATCGGCAACATCGCCAAGGCGGTCGGCGTCGACGGCCGCGAG 
GTGATGGACGTGATCTGCCAGGACCACAAGCTCAACCTGTCGCGCTACTACATGCGTCCCGGCTTCGCCTTC 
GGCGGCTCCTGCCTGCCCAAGGATGTACGCGCCCTCACCTATCGCGCCAGCCAGCTGGACGTCGAGCACCCG 
ATGCTCGGTTCGTTGATGCGCAGCAACTCCAACCAGGTGCAGAAGGCCTTCGATCTCATCACCAGCCACGAC 
ACCCGCAAGGTCGGCCTGCTCGGCCTGTCGTTCAAGGCCGGCACCGACGATTTGCGCGAAAGCCCGCTGGTG 
GAGCTGGCCGAGATGCTCATCGGCAAGGGCTACGAGTTGCGCATCTTCGACCGCAACGTCGAATACGCGCGT 
GTCCACGGGGCCAACAAGGAATACATCGAGTCGAAGATCCCGCACGTCTCCTCACTGCTGGTCTCCGACCTC 
GACGAAGTGGTGGCGAGTTCCGATGTGCTGGTGCTGGGCAATGGCGACGAGCTGTTCGTCGACCTGGTGAAC 
AAGACCCCGAGCGGCAAGAAGCTGGTCGACCTGGTGGGCTTCATGCCGCACACCACCACTGCCCAGGCCGAG 
GGCATCTGCTGGTAG