ViewGene
Locus Name:
GeneID:
Location:

GeneID:1129
TrivialName: PA14_56830
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_56830
PAO1 Ortholog Locus:PA4370
Sequence Length:1341
Protein Length:446
Start: 5061745
Stop: 5063085
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07758.1|AE004853_1 (AE004853) Insulin-cleaving metalloproteinase outer membrane protein precursor [Pseudomonas aeruginosa PAO1]
Identities = 445/446 (99%), Positives = 445/446 (99%)
Sequence:
ATGACTCGTATGCCCCTGGCCACCGCCAGTCTGCTGGCCCTCGCCATCTCCCTCGCCGGCTGCGGCGACGAC
AAGAAAGCCGAAGCGCCCGCAACACCGGCGGCCAGTACGCAGCCCGCCGCGCCCGCCGCCGCCCCGGCCACC
AAGGTCGACGAGGCCGCCGCCAAGGCGGTGATCAAGAACTACGCGGACCTCGCCGAAGCCACCTTCGCCGAT
GCCCTGAGCACCGCCAAGGACCTGCAGAAAGCCATCGACGCGTTCCTCGCCAAGCCTGACGCGGAGACCCTG
AAAGCCGCCAAGGAAGCCTGGTTCGCCGCTCGTACCCCCTACTCCCAGAGCGAAGCCTTCCGCTTCGGCAAC
GCGATCATCGACGACTGGGAAGGACAGGTTAACGCCTGGCCGCTGGACGAAGGCCTGATCGACTATGTCGCC
AAGGACTACCAGCACGCCCTGGGCAACCCCGGCGCCACCGCCAACATCGTCGCCAACACCGAGATCCAGGTC
GGCGAAGACAAGATCGACGTCAAGGAAATCACCGGCGAGAAACTGGCCAGCCTGAACGAGTTGGGCGGTTCC
GAAGCCAACGTCGCCACCGGCTACCACGCCATCGAGTTCCTCCTCTGGGGCCAGGACCTGAACGGCACCGGT
CCGGGCGCCGGCAACCGTCCCGCCACCGACTATGCCCAGGGCAAGGACTGCACCGGCGGCCATTGCGACCGT
CGCGCCGCCTACCTGAAGGCCGTCACCGACCTGCTGGTCAGCGACCTCGAATACATGGCCGGACAGTGGAAA
GCCGGCGTCGCCGACAACTACCGCGCCAAGCTGGAGGCCGAACCGGTGGATACCGGCCTGCGCAAGATGTTC
TTCGGCATGGGCAGCCTGTCCCTCGGCGAACTGGCCGGCGAGCGCATGAAGGTCGCGCTGGAGGCCAACTCC
ACCGAAGACGAGCACGACTGCTTCAGCGACGACACCCACCACACCCTGTTCTTCAACGGCAAGAGCATCCGC
AACATCTACCTCGGCGAGTACAAGCGCATCGACGGCAGCGTGGTCAAGGGCCCGAGCCTGGCCGACCTGGTC
GCCAAGGCCGACGCCGCCGCCAACGACACCCTGAAGGCCGACCTGGCCGACACCGAGGCCAAGCTGCAGGCC
ATCGTCGACAGCGCCGAGAAGGATGGCGTGCACTTCGACCAGATGATCGCTCCGGACAACAAGGACGGCCAG
CAGAAGATCCGCGACGCCATCGCCGCCCTGGTCAAGCAGACCGGCGCCATCGAGCAGGCCGCGGGCAAGCTG
GGTATCCAGGACCTGAAGCCGGACAACGCCGACCACGAGTTCTGA
Translation:
MTRMPLATASLLALAISLAGCGDDKKAEAPATPAASTQPAAPAAAPATKVDEAAAKAVIKNYADLAEATFAD
ALSTAKDLQKAIDAFLAKPDAETLKAAKEAWFAARTPYSQSEAFRFGNAIIDDWEGQVNAWPLDEGLIDYVA
KDYQHALGNPGATANIVANTEIQVGEDKIDVKEITGEKLASLNELGGSEANVATGYHAIEFLLWGQDLNGTG
PGAGNRPATDYAQGKDCTGGHCDRRAAYLKAVTDLLVSDLEYMAGQWKAGVADNYRAKLEAEPVDTGLRKMF
FGMGSLSLGELAGERMKVALEANSTEDEHDCFSDDTHHTLFFNGKSIRNIYLGEYKRIDGSVVKGPSLADLV
AKADAAANDTLKADLADTEAKLQAIVDSAEKDGVHFDQMIAPDNKDGQQKIRDAIAALVKQTGAIEQAAGKL
GIQDLKPDNADHEF*
AnnotationID:1138GeneID:1129
AnnotatorUID: diggins
Modification Date/Time: 2005-05-02 06:06:36
Gene Name:icmP
Confidence Code:1
GeneProduct:Insulin-cleaving metalloproteinase outer membrane
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(15) Membrane proteins
Alternate Gene Product Name:iron-regulated protein A
Functional Category Confidence Code:5
COGs:COG3487
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO57816.1| (AE016871) iron-regulated protein A, putative [Pseudomonas syringae
           pv. tomato str. DC3000]
          Length = 452

 Score =  677 bits (1748), Expect = 0.0
 Identities = 346/453 (76%), Positives = 376/453 (83%), Gaps = 8/453 (1%)

>gb|AAF94423.1| (AE004205) iron-regulated protein A, putative [Vibrio cholerae]
          Length = 435

 Score =  504 bits (1299), Expect = e-142
 Identities = 256/410 (62%), Positives = 300/410 (73%), Gaps = 7/410 (1%)






 
Structural Features:
COG3487, IrpA, Uncharacterized iron-regulated protein 
[Inorganic ion transport and metabolism]
CD-Length = 446 residues,  99.8% aligned
Score =  615 bits (1587), Expect = 8e-177
Identities = 290/451 (64%), Positives = 327/451 (72%), Gaps = 14/451 (3%)






   
Genomic Context:






   
Comment:


















    ReferenceID:2261




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17119




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1129_cdd.html


    		




 
URL:

















    ReferenceID:19403




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32686




  
Author/Investigator(s):
        Fricke B, Parchmann O, Kruse K, Rucknagel P, Schierhorn A, Menge S.





  
Title:
        Characterization and purification of an outer membrane metalloproteinase from Pseudomonas aeruginosa with fibrinogenolytic activity.




  
PubMed:
        10452958


MedLine:
        




    
Source:
Biochim Biophys Acta. 1999 Aug 30;1454(3):236-50.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10452958









           
Homologs By Global Alignment 

           

       



     
Gene ID:1129
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
2025
                           PA4370_tr
                           translation of PA4370
                           446
                           99.77
                           99.77
                           0
                           2282.0
     

     
     
68374
                           gb|AAG07758.1|AE004853_1
                           (AE004853) Insulin-cleaving metalloproteinase outer membrane protein precursor [Pseudomonas aeruginosa PAO1]
                           446
                           99.77
                           99.77
                           0
                           2282.0
     

     
     
68375
                           gb|AAO57816.1|
                           (AE016871) iron-regulated protein A, putative [Pseudomonas syringae pv. tomato str. DC3000]
                           456
                           76.97
                           83.55
                           14
                           1757.0
     

     
     
68376
                           gb|AAN66538.1|AE016282_6
                           (AE016777) conserved hypothetical protein [Pseudomonas putida KT2440]
                           446
                           74.43
                           83.40
                           3
                           1686.0
     

     
     
68377
                           gb|AAF94423.1|
                           (AE004205) iron-regulated protein A, putative [Vibrio cholerae O1 biovar eltor str. N16961]
                           461
                           56.39
                           67.67
                           41
                           1297.0
     

     






      

          
GC ORFID: 44131How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4370Glimmer Score: 

          
Start: 4325421Stop: 4326761

          
Length: 1341


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4370 translation of PA4370Homolog Bit Score 883.0

          
Other Homologs:  psyr_15may02_Scaffold12_revised_gene1978 (ORF: BLASTX 679.0), t_PA4370 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACTCGTATGCCCCTGGCCACCGCCAGTCTGCTGGCCCTCGCCATCTCCCTCGCCGGCTGCGGCGACGAC 
AAGAAAGCCGAAGCGCCCGCAACACCGGCGGCCAGTACGCAGCCCGCCGCGCCCGCCGCCGCCCCGGCCACC 
AAGGTCGACGAGGCCGCCGCCAAGGCGGTGATCAAGAACTACGCGGACCTCGCCGAAGCCACCTTCGCCGAT 
GCCCTGAGCACCGCCAAGGACCTGCAGAAAGCCATCGACGCGTTCCTCGCCAAGCCTGACGCGGAGACCCTG 
AAAGCCGCCAAGGAAGCCTGGTTCGCCGCTCGTACCCCCTACTCCCAGAGCGAAGCCTTCCGCTTCGGCAAC 
GCGATCATCGACGACTGGGAAGGACAGGTTAACGCCTGGCCGCTGGACGAAGGCCTGATCGACTATGTCGCC 
AAGGACTACCAGCACGCCCTGGGCAACCCCGGCGCCACCGCCAACATCGTCGCCAACACCGAGATCCAGGTC 
GGCGAAGACAAGATCGACGTCAAGGAAATCACCGGCGAGAAACTGGCCAGCCTGAACGAGTTGGGCGGTTCC 
GAAGCCAACGTCGCCACCGGCTACCACGCCATCGAGTTCCTCCTCTGGGGCCAGGACCTGAACGGCACCGGT 
CCGGGCGCCGGCAACCGTCCCGCCACCGACTATGCCCAGGGCAAGGACTGCACCGGCGGCCATTGCGACCGT 
CGCGCCGCCTACCTGAAGGCCGTCACCGACCTGCTGGTCAGCGACCTCGAATACATGGCCGGACAGTGGAAA 
GCCGGCGTCGCCGACAACTACCGCGCCAAGCTGGAGGCCGAACCGGTGGATACCGGCCTGCGCAAGATGTTC 
TTCGGCATGGGCAGCCTGTCCCTCGGCGAACTGGCCGGCGAGCGCATGAAGGTCGCGCTGGAGGCCAACTCC 
ACCGAAGACGAGCACGACTGCTTCAGCGACGACACCCACCACACCCTGTTCTTCAACGGCAAGAGCATCCGC 
AACATCTACCTCGGCGAGTACAAGCGCATCGACGGCAGCGTGGTCAAGGGCCCGAGCCTGGCCGACCTGGTC 
GCCAAGGCCGACGCCGCCGCCAACGACACCCTGAAGGCCGACCTGGCCGACACCGAGGCCAAGCTGCAGGCC 
ATCGTCGACAGCGCCGAGAAGGATGGCGTGCACTTCGACCAGATGATCGCTCCGGACAACAAGGACGGCCAG 
CAGAAGATCCGCGACGCCATCGCCGCCCTGGTCAAGCAGACCGGCGCCATCGAGCAGGCCGCGGGCAAGCTG 
GGTATCCAGGACCTGAAGCCGGACAACGCCGACCACGAGTTCTGA