ViewGene
Locus Name:
GeneID:
Location:

GeneID:1081
TrivialName: PA14_29360
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_29360
PAO1 Ortholog Locus:PA2687
Sequence Length:1341
Protein Length:446
Start: 2543109
Stop: 2541769
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06075.1|AE004696_9 (AE004696) two-component sensor PfeS [Pseudomonas aeruginosa PAO1]
Identities = 441/446 (98%), Positives = 442/446 (99%)
Sequence:
ATGCGCAGGCACCCGCTGTTATGGAAACTGGCGCTGCTGCAGGTCGGCTTCTGCCTGCTGCTGACCTGGCTG
ATCTACACCTGGGGCCTGTCGGTGGAGCGCAGCACCTACTTCCTCGCCCCGGCCGACCGCAGCTACCTGGCG
GACTACGCGCGGCAGGCGGAGGATGCCTGGCGCAGCGAGGGCGCCGCGGGCGCCGAACGCTTCCGCAAGGAA
CTGTCGGCGAAGGAAGATACCTGGGTGGCGCTGGTCGGACCGCACCTGGAAAGCCTCGGCAGCATGCCGCTG
AGCGCCGAAGAGTCGAGCCACCTGACCTTCATGCGCAAGCTCGACTGGCCGATGAGCCGGCGCCTGCAGGAC
GAACTGCCGTACGTCAGCATCGAGTTCCCCGGACATCCCGAGCAGGGCCGGCTGGTAATCCAGTTACCGGAG
CGCCTGCTGCCCGGCGGACTGACCCCCTGGACCCACCTGGTCACCCACGGCATAGTCCCGACCCTGCTGGCC
GCCCTGCTCGGCCTGCTGCTCTACCGCCACCTGGTGGTGCCGCTGAACCGCTTGCGCGATCGCGCCGACGCC
CTGCGCGCCGACGAACTGGAAAGCACTCCCCTCGCCGCACCGCTGGCGGCCCGCCGCGACGAACTCGGCGAG
CTGGCCCAGGCCCTGGAGCACATGGCCGAGCGCCTGAGCCTGAGTCTCGCCCAGCAGCGCCTGCTGCTGCGC
ACCCTGTCCCACGAACTGCGCACGCCGCTGGCGCGCTTGCGCATCGCCCACGACAGCGAGCTACCGCCGGAA
CAGTTGCGCCAGCGCCTGGATCGCGAAATCGGCGACATGCAACGACTGCTGGAAGACACCCTCGACCTCGCC
TGGATGGACACCGAGCGCCCGCAACTGCCCACCGAGCCGGTGCTGGCGCTGTCGGTGTGGGAAGCGCTGCGC
GAGGACGCCTGTTTCGAAAGCGGCTGGGACCCGGCGCGGCTACCCTGCCGCTTGGGCGTCGACTGTCGCGTC
GAGGTCCACCTGGACAGCCTGGCCCAGGCCATGGAAAACCTCCTGCGCAACGCCATCCGTCACTCGCCCGAG
GACGGCACGGTCAGCCTCGACGGCGAGCGCGAGGGCGACTTCTGGCACCTGCGCCTGCAGGACCAGGGCCCT
GGCGTGGCGGAAGACCAGTTGGAACGCATCTTCCTCCCCTACCAGCGCCTGGACGATAGCGCCGGCGAAGGT
TTCGGCCTCGGCCTGGCGATCGCCCGGCGCGCCATCGAGCTACAGGGCGGCCGGCTCTGGGCCAGCAACGGC
AAGCCCGGATTGTGCCTGCACCTGTGGCTGCCGGCAGCCGCCTGA
Translation:
MRRHPLLWKLALLQVGFCLLLTWLIYTWGLSVERSTYFLAPADRSYLADYARQAEDAWRSEGAAGAERFRKE
LSAKEDTWVALVGPHLESLGSMPLSAEESSHLTFMRKLDWPMSRRLQDELPYVSIEFPGHPEQGRLVIQLPE
RLLPGGLTPWTHLVTHGIVPTLLAALLGLLLYRHLVVPLNRLRDRADALRADELESTPLAAPLAARRDELGE
LAQALEHMAERLSLSLAQQRLLLRTLSHELRTPLARLRIAHDSELPPEQLRQRLDREIGDMQRLLEDTLDLA
WMDTERPQLPTEPVLALSVWEALREDACFESGWDPARLPCRLGVDCRVEVHLDSLAQAMENLLRNAIRHSPE
DGTVSLDGEREGDFWHLRLQDQGPGVAEDQLERIFLPYQRLDDSAGEGFGLGLAIARRAIELQGGRLWASNG
KPGLCLHLWLPAAA*
AnnotationID:1090GeneID:1081
AnnotatorUID: diggins
Modification Date/Time: 2005-04-04 19:07:22
Gene Name:pfeS
Confidence Code:1
GeneProduct:two-component sensor PfeS
Cell Localization:()
Synonyms:pirS
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(28) Two-component regulatory systems
Alternate Gene Product Name:sensor histidine kinase
Functional Category Confidence Code:5
COGs:COG0642,smart00387,cd00075
Secondary Functional Category(ies):signal transduction mechanism
EC Number:2.7.3.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66160.1|AE016244_1 (AE016776) sensor protein PfeS [Pseudomonas putida KT2440]
          Length = 442

 Score =  719 bits (1855), Expect = 0.0
 Identities = 356/445 (80%), Positives = 386/445 (86%), Gaps = 3/445 (0%)








 
Structural Features:
COG0642, BaeS, Signal transduction histidine kinase 
[Signal transduction mechanisms]
CD-Length = 336 residues,  98.5% aligned
Score =  125 bits (314), Expect = 8e-30
Identities = 103/338 (30%), Positives = 154/338 (45%), Gaps = 15/338 (4%)

smart00387, HATPase_c, Histidine kinase-like ATPase
CD-Length = 112 residues,  96.4% aligned
Score =  101 bits (254), Expect = 1e-22
Identities = 41/108 (37%), Positives = 62/108 (57%), Gaps = 3/108 (2%)

cd00075, HATPase_c, Histidine kinase-like ATPase
CD-Length = 103 residues, 100.0% aligned
Score = 94.2 bits (234), Expect = 3e-20
Identities = 43/103 (41%), Positives = 62/103 (60%), Gaps = 3/103 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:2165




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19307




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36338




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1081_cdd.html


    		




 
URL:

















    ReferenceID:36362




  
Author/Investigator(s):
        Dean CR, Poole K.





  
Title:
        Expression of the ferric enterobactin receptor (PfeA) of Pseudomonas aeruginosa: involvement of a two-component regulatory system.




  
PubMed:
        8361354


MedLine:
        




    
Source:
Mol Microbiol. 1993 Jun;8(6):1095-103.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8361354









           
Homologs By Global Alignment 

           

       



     
Gene ID:1081
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1947
                           PA2687_tr
                           translation of PA2687
                           446
                           98.87
                           99.10
                           0
                           2304.0
     

     
     
66967
                           gb|AAG06075.1|AE004696_9
                           (AE004696) two-component sensor PfeS [Pseudomonas aeruginosa PAO1]
                           446
                           98.87
                           99.10
                           0
                           2304.0
     

     
     
66968
                           gb|AAA25930.1|
                           (L07739) putative [Pseudomonas aeruginosa]
                           446
                           98.65
                           98.87
                           0
                           2299.0
     

     
     
66969
                           gb|AAN66160.1|AE016244_1
                           (AE016776) sensor protein PfeS [Pseudomonas putida KT2440]
                           446
                           79.82
                           86.54
                           4
                           1859.0
     

     
     
1948
                           PA0930_tr
                           translation of PA0930
                           448
                           53.34
                           68.75
                           5
                           1173.0
     

     






      

          
GC ORFID: 44083How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2687Glimmer Score: 

          
Start: 2410817Stop: 2412157

          
Length: 1341


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2687 translation of PA2687Homolog Bit Score 892.0

          
Other Homologs:  t_PA0930 (ORF: BLASTX 454.0), t_PA2687 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGCAGGCACCCGCTGTTATGGAAACTGGCGCTGCTGCAGGTCGGCTTCTGCCTGCTGCTGACCTGGCTG 
ATCTACACCTGGGGCCTGTCGGTGGAGCGCAGCACCTACTTCCTCGCCCCGGCCGACCGCAGCTACCTGGCG 
GACTACGCGCGGCAGGCGGAGGATGCCTGGCGCAGCGAGGGCGCCGCGGGCGCCGAACGCTTCCGCAAGGAA 
CTGTCGGCGAAGGAAGATACCTGGGTGGCGCTGGTCGGACCGCACCTGGAAAGCCTCGGCAGCATGCCGCTG 
AGCGCCGAAGAGTCGAGCCACCTGACCTTCATGCGCAAGCTCGACTGGCCGATGAGCCGGCGCCTGCAGGAC 
GAACTGCCGTACGTCAGCATCGAGTTCCCCGGACATCCCGAGCAGGGCCGGCTGGTAATCCAGTTACCGGAG 
CGCCTGCTGCCCGGCGGACTGACCCCCTGGACCCACCTGGTCACCCACGGCATAGTCCCGACCCTGCTGGCC 
GCCCTGCTCGGCCTGCTGCTCTACCGCCACCTGGTGGTGCCGCTGAACCGCTTGCGCGATCGCGCCGACGCC 
CTGCGCGCCGACGAACTGGAAAGCACTCCCCTCGCCGCACCGCTGGCGGCCCGCCGCGACGAACTCGGCGAG 
CTGGCCCAGGCCCTGGAGCACATGGCCGAGCGCCTGAGCCTGAGTCTCGCCCAGCAGCGCCTGCTGCTGCGC 
ACCCTGTCCCACGAACTGCGCACGCCGCTGGCGCGCTTGCGCATCGCCCACGACAGCGAGCTACCGCCGGAA 
CAGTTGCGCCAGCGCCTGGATCGCGAAATCGGCGACATGCAACGACTGCTGGAAGACACCCTCGACCTCGCC 
TGGATGGACACCGAGCGCCCGCAACTGCCCACCGAGCCGGTGCTGGCGCTGTCGGTGTGGGAAGCGCTGCGC 
GAGGACGCCTGTTTCGAAAGCGGCTGGGACCCGGCGCGGCTACCCTGCCGCTTGGGCGTCGACTGTCGCGTC 
GAGGTCCACCTGGACAGCCTGGCCCAGGCCATGGAAAACCTCCTGCGCAACGCCATCCGTCACTCGCCCGAG 
GACGGCACGGTCAGCCTCGACGGCGAGCGCGAGGGCGACTTCTGGCACCTGCGCCTGCAGGACCAGGGCCCT 
GGCGTGGCGGAAGACCAGTTGGAACGCATCTTCCTCCCCTACCAGCGCCTGGACGATAGCGCCGGCGAAGGT 
TTCGGCCTCGGCCTGGCGATCGCCCGGCGCGCCATCGAGCTACAGGGCGGCCGGCTCTGGGCCAGCAACGGC 
AAGCCCGGATTGTGCCTGCACCTGTGGCTGCCGGCAGCCGCCTGA