ViewGene
Locus Name:
GeneID:
Location:

GeneID:1072
TrivialName: PA14_64110
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_64110
PAO1 Ortholog Locus:PA4848
Sequence Length:1350
Protein Length:449
Start: 5713444
Stop: 5714793
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08233.1|AE004898_4 (AE004898) biotin carboxylase [Pseudomonas aeruginosa PAO1]
Identities = 449/449 (100%), Positives = 449/449 (100%)
Sequence:
ATGTTGGAAAAAGTGCTGATCGCCAACCGCGGCGAAATCGCCTTGCGCATCCTTCGCGCATGCAAGGAGCTG
GGGATCAAGACGGTGGCGGTACACTCCACCGCCGACCGCGAGTTGATGCACCTGTCGCTCGCCGACGAATCG
GTGTGCATCGGTCCGGCCCCGGCCACCCAGTCGTACCTGCAGATCCCGGCGATCATCGCCGCGGCCGAGGTC
ACCGGCGCCACCGCGATCCACCCCGGCTACGGCTTCCTCGCCGAGAACGCCGACTTCGCCGAGCAGATCGAA
CGCTCCGGCTTCACCTTCGTCGGCCCGACCGCCGAGGTGATCCGCCTGATGGGCGACAAGGTCTCGGCCAAG
GACGCCATGAAGCGCGCCGGCGTCCCCACCGTGCCGGGCTCCGACGGCCCGCTGCCGGAAGATGAAGAGACC
GCCCTGGCGATCGCCCGCGAGGTCGGCTACCCGGTGATCATCAAGGCCGCCGGCGGCGGCGGTGGGCGCGGC
ATGCGCGTGGTCTACGACGAGTCCGAGCTGATCAAGTCGGCCAAGCTGACCCGCACCGAGGCCGGCGCGGCG
TTCGGCAACCCGATGGTCTACCTGGAGAAGTTCCTGACCAACCCGCGCCACGTGGAAGTCCAGGTGCTTTCC
GACGGCCAGGGCAACGCCATCCACCTCGGCGACCGCGACTGCTCCCTGCAGCGCCGCCACCAGAAGGTGATC
GAAGAGGCGCCGGCCCCCGGCATCGACGAGAAGGCCCGCCAGGAAGTCTTCGCCCGCTGCGTCCAGGCCTGC
ATCGAGATCGGCTACCGCGGCGCCGGCACCTTCGAGTTCCTCTACGAGAACGGCCGCTTCTACTTCATCGAG
ATGAACACTCGCGTGCAGGTGGAGCACCCGGTATCGGAGATGGTCACCGGTGTCGACATCGTCAAGGAGATG
CTGCGCATCGCCTCCGGCGAGAAGCTCTCGATCCGCCAGGAGGACGTGGTCATCCGCGGCCATGCGCTGGAA
TGCCGGATCAACGCCGAAGACCCGAAGACCTTCATGCCCAGCCCGGGCAAGGTCAAGCACTTCCACGCCCCC
GGCGGCAACGGCGTGCGCGTCGACTCGCACCTCTACAGCGGCTACAGCGTACCGCCGAACTACGACTCGCTG
GTCGGCAAGGTCATCACCTACGGTGCCGACCGCGACGAGGCGCTGGCGCGGATGCGCAATGCCCTAGACGAG
TTGATCGTCGACGGTATCAAGACCAATACCGAACTGCACAAGGACCTGGTGCGCGACGCCGCCTTCTGCAAG
GGCGGGGTGAACATCCACTACCTGGAGAAGAAACTGGGTATGGACAAGCACTGA
Translation:
MLEKVLIANRGEIALRILRACKELGIKTVAVHSTADRELMHLSLADESVCIGPAPATQSYLQIPAIIAAAEV
TGATAIHPGYGFLAENADFAEQIERSGFTFVGPTAEVIRLMGDKVSAKDAMKRAGVPTVPGSDGPLPEDEET
ALAIAREVGYPVIIKAAGGGGGRGMRVVYDESELIKSAKLTRTEAGAAFGNPMVYLEKFLTNPRHVEVQVLS
DGQGNAIHLGDRDCSLQRRHQKVIEEAPAPGIDEKARQEVFARCVQACIEIGYRGAGTFEFLYENGRFYFIE
MNTRVQVEHPVSEMVTGVDIVKEMLRIASGEKLSIRQEDVVIRGHALECRINAEDPKTFMPSPGKVKHFHAP
GGNGVRVDSHLYSGYSVPPNYDSLVGKVITYGADRDEALARMRNALDELIVDGIKTNTELHKDLVRDAAFCK
GGVNIHYLEKKLGMDKH*
AnnotationID:1081GeneID:1072
AnnotatorUID: diggins
Modification Date/Time: 2005-04-26 06:06:13
Gene Name:accC
Confidence Code:1
GeneProduct:biotin carboxylase
Cell Localization:()
Synonyms:fabG
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:acetyl-CoA carboxylase
Functional Category Confidence Code:5
COGs:COG0439,pfam02786
Secondary Functional Category(ies):
EC Number:6.3.4.14
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66185.1|AE016246_2 (AE016776) acetyl-CoA carboxylase, biotin carboxylase [Pseudomonas
           putida KT2440]
          Length = 451

 Score =  808 bits (2087), Expect = 0.0
 Identities = 397/443 (89%), Positives = 418/443 (94%)

>gb|AAO58290.1| (AE016873) acetyl-CoA carboxylase, biotin carboxylase [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 447

 Score =  759 bits (1961), Expect = 0.0
 Identities = 374/444 (84%), Positives = 403/444 (90%)

>gb|AAF93469.1| (AE004117) acetyl-CoA carboxylase, biotin carboxylase [Vibrio
           cholerae]
          Length = 447

 Score =  684 bits (1766), Expect = 0.0
 Identities = 330/446 (73%), Positives = 388/446 (86%)






 
Structural Features:
COG0439, AccC, Biotin carboxylase [Lipid metabolism]
CD-Length = 449 residues,  99.6% aligned
Score =  624 bits (1610), Expect = 8e-180
Identities = 292/448 (65%), Positives = 360/448 (80%), Gaps = 3/448 (0%)

pfam02786, CPSase_L_D2, Carbamoyl-phosphate synthase L chain, 
ATP binding domain.
CD-Length = 236 residues,  92.4% aligned
Score =  281 bits (719), Expect = 1e-76
Identities = 108/222 (48%), Positives = 137/222 (61%), Gaps = 6/222 (2%)







   
Genomic Context:






   
Comment:


















    ReferenceID:2147




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19289




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:35212




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1072_cdd.html


    		




 
URL:

















    ReferenceID:35978




  
Author/Investigator(s):
        J Bacteriol. 1993 Nov;175(21):6881-9.





  
Title:
        Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.




  
PubMed:
        7693652


MedLine:
        




    
Source:
J Bacteriol. 1993 Nov;175(21):6881-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7693652









           
Homologs By Global Alignment 

           

       



     
Gene ID:1072
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1928
                           PA4848_tr
                           translation of PA4848
                           449
                           99.99
                           99.99
                           0
                           2310.0
     

     
     
66494
                           gb|AAA16041.1|
                           (L14612) biotin carboxylase [Pseudomonas aeruginosa]
                           449
                           99.99
                           99.99
                           0
                           2310.0
     

     
     
66493
                           gb|AAG08233.1|AE004898_4
                           (AE004898) biotin carboxylase [Pseudomonas aeruginosa PAO1]
                           449
                           99.99
                           99.99
                           0
                           2310.0
     

     
     
66495
                           gb|AAN66185.1|AE016246_2
                           (AE016776) acetyl-CoA carboxylase, biotin carboxylase [Pseudomonas putida KT2440]
                           452
                           87.83
                           92.69
                           4
                           2085.0
     

     
     
66496
                           gb|AAO58290.1|
                           (AE016873) acetyl-CoA carboxylase, biotin carboxylase [Pseudomonas syringae pv. tomato str. DC3000]
                           449
                           83.29
                           89.75
                           2
                           1959.0
     

     






      

          
GC ORFID: 44074How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4848Glimmer Score: 

          
Start: 4977124Stop: 4978473

          
Length: 1350


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4848 translation of PA4848Homolog Bit Score 894.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5770 (ORF: BLASTX 766.0), t_PA0494 (ORF: BLASTX 473.0), t_PA4848 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTTGGAAAAAGTGCTGATCGCCAACCGCGGCGAAATCGCCTTGCGCATCCTTCGCGCATGCAAGGAGCTG 
GGGATCAAGACGGTGGCGGTACACTCCACCGCCGACCGCGAGTTGATGCACCTGTCGCTCGCCGACGAATCG 
GTGTGCATCGGTCCGGCCCCGGCCACCCAGTCGTACCTGCAGATCCCGGCGATCATCGCCGCGGCCGAGGTC 
ACCGGCGCCACCGCGATCCACCCCGGCTACGGCTTCCTCGCCGAGAACGCCGACTTCGCCGAGCAGATCGAA 
CGCTCCGGCTTCACCTTCGTCGGCCCGACCGCCGAGGTGATCCGCCTGATGGGCGACAAGGTCTCGGCCAAG 
GACGCCATGAAGCGCGCCGGCGTCCCCACCGTGCCGGGCTCCGACGGCCCGCTGCCGGAAGATGAAGAGACC 
GCCCTGGCGATCGCCCGCGAGGTCGGCTACCCGGTGATCATCAAGGCCGCCGGCGGCGGCGGTGGGCGCGGC 
ATGCGCGTGGTCTACGACGAGTCCGAGCTGATCAAGTCGGCCAAGCTGACCCGCACCGAGGCCGGCGCGGCG 
TTCGGCAACCCGATGGTCTACCTGGAGAAGTTCCTGACCAACCCGCGCCACGTGGAAGTCCAGGTGCTTTCC 
GACGGCCAGGGCAACGCCATCCACCTCGGCGACCGCGACTGCTCCCTGCAGCGCCGCCACCAGAAGGTGATC 
GAAGAGGCGCCGGCCCCCGGCATCGACGAGAAGGCCCGCCAGGAAGTCTTCGCCCGCTGCGTCCAGGCCTGC 
ATCGAGATCGGCTACCGCGGCGCCGGCACCTTCGAGTTCCTCTACGAGAACGGCCGCTTCTACTTCATCGAG 
ATGAACACTCGCGTGCAGGTGGAGCACCCGGTATCGGAGATGGTCACCGGTGTCGACATCGTCAAGGAGATG 
CTGCGCATCGCCTCCGGCGAGAAGCTCTCGATCCGCCAGGAGGACGTGGTCATCCGCGGCCATGCGCTGGAA 
TGCCGGATCAACGCCGAAGACCCGAAGACCTTCATGCCCAGCCCGGGCAAGGTCAAGCACTTCCACGCCCCC 
GGCGGCAACGGCGTGCGCGTCGACTCGCACCTCTACAGCGGCTACAGCGTACCGCCGAACTACGACTCGCTG 
GTCGGCAAGGTCATCACCTACGGTGCCGACCGCGACGAGGCGCTGGCGCGGATGCGCAATGCCCTAGACGAG 
TTGATCGTCGACGGTATCAAGACCAATACCGAACTGCACAAGGACCTGGTGCGCGACGCCGCCTTCTGCAAG 
GGCGGGGTGAACATCCACTACCTGGAGAAGAAACTGGGTATGGACAAGCACTGA