ViewGene
Locus Name:
GeneID:
Location:

GeneID:1042
TrivialName: PA14_22620
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_22620
PAO1 Ortholog Locus:PA3217
Sequence Length:1392
Protein Length:463
Start: 1968262
Stop: 1966871
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06605.1|AE004745_2 (AE004745) probable adenylate cyclase [Pseudomonas aeruginosa PAO1]
Identities = 462/463 (99%), Positives = 462/463 (99%)
Sequence:
ATGAAGCCTACCCTCCCCGACCGCTCGCCGACGAGCCGGTCCGTCGCGTCCATGCGTGAATACTATTCGCGC
GTGCTGGCCTATATCGCCTGTGGCGCCAGCATCGCGGCGGGAACCTACACCCAGTATTTCAGCTACGGCATC
CTCTGGATGGTGCCCTATGCGCTGCTCTACCCGCACCTGGCGTACCACCTCGGCCAGCGCTTCCGCCAGCAC
GACCCGCGCAAGGTGACCCGCGCCCTGCTCGCGGTCGACGCCGTGCACTGTGGCCTGGGCATGGCGCTGCTC
GGCTTCTCCGTGGTGCCCAGCCTGATGTTCCTGCTGGTGCTGAGCTTCACCGCGCTGGTCATCGGCGGCCTG
CGCCTGCTCGGCATGGCCCTGCTGGTATCGGCCAGCAGCGCCCTGCTGGTCGCCGTGCTCGTCGCCCCGCCG
CTGCTGGGCAATACCTCGGTCGAGGTGGCCGCGGTCAGCATCCTGTTCTGCGGACTGTACATCTGCATCACC
GCCTTCTTCGGCCACCAGCAGGGCCTGCGCCTGGCCCAGGTGCGCCAGGAGATCGCCCGCGAGCAGGAAAAG
GCCGCGCGGCTCGCGCGCAACCTGGCCAAGTACCTGTCGCCGCAGGTCTGGGAAATGATCTTCAGCGGCAAG
AAGAGCGTGCGCCTGGAAACCCAGCGCAAGAAGCTCACCGTGTTCTTCTCCGACATCCGCGGCTTCACCGAG
CTATCCGAGGAGCTGGAAGCCGAGGCCCTGACCGACCTGCTCAACAACTACCTCAACGAGATGTCGAAGATC
GCCCTCAAGTACGGCGGCACCATCGACAAGTTCGTCGGCGACTGCGTCATGGTGTTCTTCGGCGACCCCAGC
ACCCAGGGCGCGAAGAAGGACGCGGTGGCTGCGGTATCGATGGGCATCGCCATGCGCAAGCACATGAAGGTG
CTGCGCCAGCAGTGGCGGGCCCAGGGCATCACCAAGCCGCTGGAAATCCGCATGGGCATCAACACCGGCTAT
TGCACGGTGGGTAACTTCGGCGCCGACACGCGCATGGACTACACCATCATCGGCCGCGAGGTGAACCTCGCC
AGCCGCCTGGAAAGCGCCTCGGAAGCCGGCGAAATCCTCATTTCCCACGAGACCTACTCGCTGATCAAGGAC
GTGATCATGTGCCGCGACAAGGGCCAGATCGCGGTCAAGGGCTTCAGCCGCCCGGTGCAGATCTACCAGGTG
GTGGACTCGCGCCGCGACCTCGGCGCCGCGCCCAGCTACGTCGAGCACGAATTGCCCGGCTTCTCCATGTAC
CTGGACACCAACAACATCCAGAACTACGACAAGGAACGGGTCATCCAGGCCCTGCAACAGGCCGCCGAGCGC
CTACGCGACAAGGTCATCCTCTGA
Translation:
MKPTLPDRSPTSRSVASMREYYSRVLAYIACGASIAAGTYTQYFSYGILWMVPYALLYPHLAYHLGQRFRQH
DPRKVTRALLAVDAVHCGLGMALLGFSVVPSLMFLLVLSFTALVIGGLRLLGMALLVSASSALLVAVLVAPP
LLGNTSVEVAAVSILFCGLYICITAFFGHQQGLRLAQVRQEIAREQEKAARLARNLAKYLSPQVWEMIFSGK
KSVRLETQRKKLTVFFSDIRGFTELSEELEAEALTDLLNNYLNEMSKIALKYGGTIDKFVGDCVMVFFGDPS
TQGAKKDAVAAVSMGIAMRKHMKVLRQQWRAQGITKPLEIRMGINTGYCTVGNFGADTRMDYTIIGREVNLA
SRLESASEAGEILISHETYSLIKDVIMCRDKGQIAVKGFSRPVQIYQVVDSRRDLGAAPSYVEHELPGFSMY
LDTNNIQNYDKERVIQALQQAAERLRDKVIL*
AnnotationID:1051GeneID:1042
AnnotatorUID: danlee
Modification Date/Time: 2006-01-27 15:03:52
Gene Name:cyaB
Confidence Code:1
GeneProduct:CyaB
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(20) Putative enzymes
Alternate Gene Product Name:putative Adenylate/Guanylate cyclase
Functional Category Confidence Code:5
COGs:smart00044,pfam00211,COG2114
Secondary Functional Category(ies):signal transduction mechanism
EC Number:4.6.1.2
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAK64961.1| (AE007222) adenylate cyclase, putative [Sinorhizobium meliloti]
          Length = 809

 Score =  278 bits (711), Expect = 5e-74
 Identities = 134/280 (47%), Positives = 198/280 (70%)








 
Structural Features:
smart00044, CYCc, Adenylyl- / guanylyl cyclase, catalytic domain
CD-Length = 194 residues,  95.4% aligned
Score =  123 bits (311), Expect = 4e-29
Identities = 66/195 (33%), Positives = 96/195 (49%), Gaps = 10/195 (5%)

pfam00211, Guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.
CD-Length = 186 residues,  95.2% aligned
Score =  136 bits (344), Expect = 5e-33
Identities = 57/185 (30%), Positives = 88/185 (47%), Gaps = 12/185 (6%)

COG2114, CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) 
[Signal transduction mechanisms]
CD-Length = 227 residues,  78.0% aligned
Score =  150 bits (379), Expect = 4e-37
Identities = 73/193 (37%), Positives = 115/193 (59%), Gaps = 18/193 (9%)






   
Genomic Context:






   
Comment:


















    ReferenceID:2087




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19229




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32328




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:1042_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:1042
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1879
                           PA3217_tr
                           translation of PA3217
                           463
                           99.78
                           99.78
                           0
                           2333.0
     

     
     
65009
                           gb|AAG06605.1|AE004745_2
                           (AE004745) probable adenylate cyclase [Pseudomonas aeruginosa PAO1]
                           463
                           99.78
                           99.78
                           0
                           2333.0
     

     
     
65011
                           emb|CAE27237.1|
                           (BX572598) putative Adenylate/Guanylate cyclase [Rhodopseudomonas palustris CGA009]
                           559
                           31.66
                           45.43
                           131
                           676.0
     

     
     
65012
                           dbj|BAC52889.1|
                           (AP005962) bll7624 [Bradyrhizobium japonicum USDA 110]
                           587
                           28.96
                           43.10
                           157
                           651.0
     

     
     
65010
                           gb|AAK64961.1|
                           (AE007222) adenylate cyclase, putative [Sinorhizobium meliloti]
                           820
                           23.90
                           35.85
                           368
                           677.0
     

     






      

          
GC ORFID: 44044How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3217Glimmer Score: 

          
Start: 2985669Stop: 2987060

          
Length: 1392


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3217 translation of PA3217Homolog Bit Score 903.0

          
Other Homologs:  t_PA3217 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAAGCCTACCCTCCCCGACCGCTCGCCGACGAGCCGGTCCGTCGCGTCCATGCGTGAATACTATTCGCGC 
GTGCTGGCCTATATCGCCTGTGGCGCCAGCATCGCGGCGGGAACCTACACCCAGTATTTCAGCTACGGCATC 
CTCTGGATGGTGCCCTATGCGCTGCTCTACCCGCACCTGGCGTACCACCTCGGCCAGCGCTTCCGCCAGCAC 
GACCCGCGCAAGGTGACCCGCGCCCTGCTCGCGGTCGACGCCGTGCACTGTGGCCTGGGCATGGCGCTGCTC 
GGCTTCTCCGTGGTGCCCAGCCTGATGTTCCTGCTGGTGCTGAGCTTCACCGCGCTGGTCATCGGCGGCCTG 
CGCCTGCTCGGCATGGCCCTGCTGGTATCGGCCAGCAGCGCCCTGCTGGTCGCCGTGCTCGTCGCCCCGCCG 
CTGCTGGGCAATACCTCGGTCGAGGTGGCCGCGGTCAGCATCCTGTTCTGCGGACTGTACATCTGCATCACC 
GCCTTCTTCGGCCACCAGCAGGGCCTGCGCCTGGCCCAGGTGCGCCAGGAGATCGCCCGCGAGCAGGAAAAG 
GCCGCGCGGCTCGCGCGCAACCTGGCCAAGTACCTGTCGCCGCAGGTCTGGGAAATGATCTTCAGCGGCAAG 
AAGAGCGTGCGCCTGGAAACCCAGCGCAAGAAGCTCACCGTGTTCTTCTCCGACATCCGCGGCTTCACCGAG 
CTATCCGAGGAGCTGGAAGCCGAGGCCCTGACCGACCTGCTCAACAACTACCTCAACGAGATGTCGAAGATC 
GCCCTCAAGTACGGCGGCACCATCGACAAGTTCGTCGGCGACTGCGTCATGGTGTTCTTCGGCGACCCCAGC 
ACCCAGGGCGCGAAGAAGGACGCGGTGGCTGCGGTATCGATGGGCATCGCCATGCGCAAGCACATGAAGGTG 
CTGCGCCAGCAGTGGCGGGCCCAGGGCATCACCAAGCCGCTGGAAATCCGCATGGGCATCAACACCGGCTAT 
TGCACGGTGGGTAACTTCGGCGCCGACACGCGCATGGACTACACCATCATCGGCCGCGAGGTGAACCTCGCC 
AGCCGCCTGGAAAGCGCCTCGGAAGCCGGCGAAATCCTCATTTCCCACGAGACCTACTCGCTGATCAAGGAC 
GTGATCATGTGCCGCGACAAGGGCCAGATCGCGGTCAAGGGCTTCAGCCGCCCGGTGCAGATCTACCAGGTG 
GTGGACTCGCGCCGCGACCTCGGCGCCGCGCCCAGCTACGTCGAGCACGAATTGCCCGGCTTCTCCATGTAC 
CTGGACACCAACAACATCCAGAACTACGACAAGGAACGGGTCATCCAGGCCCTGCAACAGGCCGCCGAGCGC 
CTACGCGACAAGGTCATCCTCTGA