RPS-BLAST 2.2.9 [May-01-2004]
Query= local sequence: lcl|tmpseq_0 unnamed protein product
         (105 letters)

Database: cdd.v2.00

	PSSMs producing significant alignments:		Score (bits)	E value
	gnl|CDD|5390	cd00189, TPR, Tetratricopeptide repeat domain; typically conta...	40.1	6e-05
	gnl|CDD|13919	COG4783, COG4783, Putative Zn-dependent protease, contains TPR...	46.9	6e-07
	gnl|CDD|12402	COG3063, PilF, Tfp pilus assembly protein PilF [Cell motility ...	43.8	4e-06
	gnl|CDD|14107	COG4976, COG4976, Predicted methyltransferase (contains TPR re...	35.3	0.002
	gnl|CDD|14140	COG5010, TadD, Flp pilus assembly protein TadD, contains TPR r...	33.8	0.005

gnl|CDD|5390, cd00189, TPR, Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here

             CD-Length = 100 residues,  77.0% aligned
             Score = 40.1 bits (93), Expect = 6e-05

Query:  3    IEGLEKMLAKGVDNALLRFGLGKGYLDAGDAERATEHLQRCVEQDPTYSAGWKLLGKARQ  62
Sbjct:  20   LEYYEKALELDPDNADAYYNLAAAYYKLGKYEEALEDYEKALELDPDNAKAYYNLGLAYY  79

Query:  63   AAGDLAGARQAWEQGLA  79
Sbjct:  80   KLGKYEEALEAYEKALE  96

---

             CD-Length = 484 residues, only  19.6% aligned
             Score = 46.9 bits (111), Expect = 6e-07

Query:  3    IEGLEKMLAKGVDNALLRFGLGKGYLDAGDAERATEHLQRCVEQDPTYSAGWKLLGKARQ  62
Sbjct:  360  IERLKKALALDPNSPLLQLNLAQALLKGGKPQEAIRILNRYLFNDPEDPNGWDLLAQAYA  419

Query:  63   AAGDLAGARQAWEQGLAAAATHGDKQAEKEMTVFLRKL  100
Sbjct:  420  ELGNRAEALLARAEGYALA---GRLEQAIIFLMRASQQ  454

             CD-Length = 250 residues, only  26.8% aligned
             Score = 43.8 bits (103), Expect = 4e-06

Query:  20   RFGLGKGYLDAGDAERATEHLQRCVEQDPTYSAGWKLLGKARQAAGDLAGARQAWEQGLA  79
Sbjct:  38   RLQLALGYLQQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALS  97

Query:  80   AAATHGD  86
Sbjct:  98   LAPNNGD  104

             CD-Length = 287 residues, only  19.2% aligned
             Score = 35.3 bits (81), Expect = 0.002

Query:  28   LDAGDAERATEHLQRCVEQDPTYSAGWKLLGKARQAAGDLAGARQAWEQGLAAAA  82
Sbjct:  6    AESGDAEAAAELYNQALELAPEWAAGWFRLGEYTEKAGEFDAAAAAYEEVLELDP  60

             CD-Length = 257 residues, only  28.0% aligned
             Score = 33.8 bits (77), Expect = 0.005

Query:  10   LAKGVDNALLRFGLGKGYLDAGDAERATEHLQRCVEQDPTYSAGWKLLGKARQAAGDLAG  69
Sbjct:  94   IAYPKDRELLA-AQGKNQIRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGRFDE  152

Query:  70   ARQAWEQGLAAAA  82
Sbjct:  153  ARRAYRQALELAP  165