RPS-BLAST 2.2.9 [May-01-2004]
Query= local sequence: lcl|tmpseq_0 unnamed protein product
         (257 letters)

Database: cdd.v2.00

	PSSMs producing significant alignments:		Score (bits)	E value
	gnl|CDD|24304	smart00563, PlsC, Phosphate acyltransferases; Function in phos...	91.2	1e-19
	gnl|CDD|25778	pfam01553, Acyltransferase, Acyltransferase. This family conta...	83.5	2e-17
	gnl|CDD|10079	COG0204, PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase ...	133	3e-32
	gnl|CDD|11829	COG2121, COG2121, Uncharacterized protein conserved in bacteri...	38.0	0.001

gnl|CDD|24304, smart00563, PlsC, Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.

             CD-Length = 118 residues,  98.3% aligned
             Score = 91.2 bits (226), Expect = 1e-19

Query:  76   CVILSKHQSTWETFFLSGFFEPLSQ----VLKRELLYVPFFGWALALLKPIAIDRSQPKL  131
Sbjct:  1    ALVVANHQSFLDPLVLSALLPRKLRRVRFVAKKELFYVPLLGWLLRLAGAIFIDRSRGRK  60

Query:  132  ALKQLAKQGDECLKKGAWVLIFPEGTRIPVGQMGKFSRGGTALAVNAGLPVLPIAHN  188
Sbjct:  61   DRAALREAV-RLLREGEWLLIFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR  116

---

gnl|CDD|25778, pfam01553, Acyltransferase, Acyltransferase. This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.

             CD-Length = 132 residues,  98.5% aligned
             Score = 83.5 bits (206), Expect = 2e-17

Query:  62   RYEVRGLENIPEK-PCVILSKHQSTWETFFLSGFF----EPLSQVLKRELLYVPFFGWAL  116
Sbjct:  1    RIRVHGLENLPEAGPAIVVANHQSWLDPLVLSLLLYKRPDRPVFIAKKILLTDPLLGPLM  60

Query:  117  ALLKPIAIDRSQPKLALKQLAKQGDECLKKGAWVLIFPEGTRIPVGQMGKFSRGGTALAV  176
Sbjct:  61   RLLGLIFIDRENKKRALEALREAVELLRKGELPVLIFPEGTRSRNGRLLPFKKGAFHLAV  120

Query:  177  NAGLPVLPIA  186
Sbjct:  121  QAGVPIVPVA  130

---

             CD-Length = 255 residues,  92.2% aligned
             Score =  133 bits (334), Expect = 3e-32

Query:  12   FYLLLSASAFVWGTLSFFIAPILPFRARYRFVVQNWCRFAIWLTRVVAGIRYEVRGLENI  71
Sbjct:  1    LRLALLLILVILFLLLPLPLALIALFRLRRPVLRRWLRFLVLLLLLLFGLRVEVEGLENL  60

Query:  72   PE-KPCVILSKHQSTWETFFLSGFF---EPLSQVLKRELLYVPFFGWALALLKPIAIDRS  127
Sbjct:  61   PKGGPALVVANHQSFLDPLLLSLALPRRGPVRFVAKKELFKVPLLGWLLRLLGAIPVDRE  120

Query:  128  QPKLALKQLAKQGDECLKKGAWVLIFPEGTRIPVGQ-MGKFSRGGTALAVNAGLPVLPIA  186
Sbjct:  121  NPDDETLRAAVA--RLKAGGRSLVIFPEGTRSRGGEELLPFKRGAARLALEAGVPIVPVA  178

Query:  187  HNAGQYWPKAGWAKYPGTIQVVIGPAMHAEGEGPRAIAELNQRAEAWVSETMAEISPIQQ  246
Sbjct:  179  IVGAE---ELFPSLKKGKVKVRIGPPIDISALPEPLLPELAEAVEQLARPILLELLPRYA  235

             CD-Length = 214 residues,  96.7% aligned
             Score = 38.0 bits (88), Expect = 0.001

Query:  33   ILPFRARYRFVVQNWCRFAIWLTRVV-AGIRYEVRGLENIP---EKPCVILSKHQSTWET  88
Sbjct:  1    LKKFLKNSKFVISILTSLLYGYLRLVYLTSRWKAGGADNNALANEKPGIVAFWHGQ----  56

Query:  89   FFLSGFFEP--------LSQVLKRELLYVPFFGWALALLKPIAIDRSQPKLALKQLAKQG  140
Sbjct:  57   LALGPFAFPKGKKIYAMVSPSRDGELIARL-----LEKFGLRVIRGSSNKGGISAL-RAL  110

Query:  141  DECLKKGAWVLIFPEGTRIPVGQMGKFSRGGTALAVNAGLPVLPIAHNAGQYWPKAGWAK  200
Sbjct:  111  LKALKQGKSIAITPDGPKGPVHKIGD---GIIALAQKSGVPIIPVGVATSRCWRLKTWDK  167

Query:  201  YP-----GTIQVVIGPAMHAEGEGPRAIAELNQRAEAWVSETMAE  240
Sbjct:  168  TIIPLPFGKIKIVLGEPIEVDAD-----KDKEELEEKRQEVSLAL  207