Score E
Sequences producing significant alignments: (bits) Value
gnl|CDD|10116 COG0241, HisB, Histidinol phosphatase and rel... 199 3e-52
gnl|CDD|10417 COG0546, Gph, Predicted phosphatases [General... 59 5e-10
gnl|CDD|25595 pfam00702, Hydrolase, haloacid dehalogenase-l... 50 5e-07
gnl|CDD|10431 COG0560, SerB, Phosphoserine phosphatase [Ami... 36 0.005
gnl|CDD|10517 COG0647, NagD, Predicted sugar phosphatases o... 36 0.006
gnl|CDD|19063 KOG1274, KOG1274, WD40 repeat protein [Genera... 35 0.013
gnl|CDD|10740 COG1011, COG1011, Predicted hydrolase (HAD su... 33 0.050
gnl|CDD|20668 KOG2882, KOG2882, p-Nitrophenyl phosphatase [... 31 0.17
gnl|CDD|13479 COG4229, COG4229, Predicted enolase-phosphata... 30 0.28
gnl|CDD|20894 KOG3109, KOG3109, Haloacid dehalogenase-like ... 30 0.41
gnl|CDD|6485 pfam01526, Transposase_7, Transposase. This fa... 28 1.0
gnl|CDD|10432 COG0561, Cof, Predicted hydrolases of the HAD... 28 1.8
gnl|CDD|20062 KOG2276, KOG2276, Metalloexopeptidases [Amino... 27 2.4
gnl|CDD|20825 KOG3040, KOG3040, Predicted sugar phosphatase... 27 2.7
gnl|CDD|10507 COG0637, COG0637, Predicted phosphatase/phosp... 27 3.0
gnl|CDD|20416 KOG2630, KOG2630, Enolase-phosphatase E-1 [Am... 26 3.5
gnl|CDD|12331 COG2987, HutU, Urocanate hydratase [Amino aci... 26 6.1
gnl|CDD|23845 pfam05621, TniB, Bacterial TniB protein. This... 26 6.3
gnl|CDD|15656 pfam04358, DsrC, DsrC like protein. One famil... 26 6.4
gnl|CDD|21332 KOG3549, KOG3549, Syntrophins (type gamma) [E... 26 7.2
gnl|CDD|18615 KOG0822, KOG0822, Protein kinase inhibitor [C... 25 7.8
>gnl|CDD|10116 COG0241, HisB, Histidinol phosphatase and related phosphatases [Amino
acid transport and metabolism]
Length = 181
Score = 199 bits (507), Expect = 3e-52
Identities = 79/173 (45%), Positives = 108/173 (62%), Gaps = 2/173 (1%)
Query: 1 MSRSLLILDRDGVINLDSDDYIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARG 60
Sbjct: 3 KDQKALFLDRDGTINIDKGDYVDSLDDFQFIPGVIPALLKLQRAGYKLVVVTNQSGIGRG 62
Query: 61 YYDLAVLEAMHARLRELVAEQGGEVGLIVYCPHGPDDGCDCRKPKPGMLRQIGKHYGVDL 120
Sbjct: 63 YFTEADFDKLHNKMLKILASQGVKIDGILYCPHHPEDNCDCRKPKPGMLLSALKEYNIDL 122
Query: 121 SGIWFVGDSIGDLEAARAVDCQPVLVKTGKGVRTLGKPLPEGTLIFDDLAAVA 173
Sbjct: 123 SRSYVVGDRLTDLQAAENAGIKGVLVLTGIGVTTDGA--GRAKWVFDSLAEFA 173
>gnl|CDD|10417 COG0546, Gph, Predicted phosphatases [General function prediction
only]
Length = 220
Score = 59.4 bits (143), Expect = 5e-10
Identities = 36/161 (22%), Positives = 56/161 (34%), Gaps = 21/161 (13%)
Query: 19 DDYIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARGYYDLAVLEAMHARLRELV 78
Sbjct: 79 LTAYAELLESRLFPGVKELLAALKSAGYKLGIVTNKP---------------ERELDILL 123
Query: 79 AEQG-GEVGLIVYCPHGPDDGCDCRKPKPGMLRQIGKHYGVDLSGIWFVGDSIGDLEAAR 137
Sbjct: 124 KALGLADYFDVIVG----GDDVPPPKPDPEPLLLLLEKLGLDPEEALMVGDSLNDILAAK 179
Query: 138 AVDCQPVLVKTGKGVRTLGKPLPEGTLIFDDLAAVASALLQ 178
Sbjct: 180 AAGVPAVGVTWGYNSREELAQA-GADVVIDSLAELLALLAE 219
>gnl|CDD|25595 pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This
family are structurally different from the alpha/ beta
hydrolase family (pfam00561). This family includes
L-2-haloacid dehalogenase, epoxide hydrolases and
phosphatases. The structure of the family consists of two
domains. One is an inserted four helix bundle, which is
the least well conserved region of the alignment. The
rest of the fold is composed of the core alpha/beta
domain
Length = 197
Score = 49.6 bits (117), Expect = 5e-07
Identities = 26/120 (21%), Positives = 39/120 (32%), Gaps = 18/120 (15%)
Query: 30 PIPSSIEAIARLSQAGWTVAVATNQSGIARGYYDLAVLEAMHARLRELVAEQGGEVGLIV 89
Sbjct: 96 LYPGAREALKALKERGIKLAILTNGDRA-------------NAEAVLELLGLADLFDVIV 142
Query: 90 YCPHGPDDGCDCRKPKPGMLRQIGKHYGVDLSGIWFVGDSIGDLEAARAVDCQPVLVKTG 149
Sbjct: 143 DS-----DDVGPVKPKPEIFLLALERLGVKPEEVLMVGDGVNDAPALAAAGVGVAMVNGG 197
>gnl|CDD|10431 COG0560, SerB, Phosphoserine phosphatase [Amino acid transport and
metabolism]
Length = 212
Score = 36.1 bits (83), Expect = 0.005
Identities = 32/145 (22%), Positives = 54/145 (37%), Gaps = 12/145 (8%)
Query: 15 NLDSDDYIKTLDEWIPI-PSSIEAIARLSQAGWTVAVAT-NQSGIARGYYDLAVLEAMHA 72
Sbjct: 62 GLPVEVLEEVREEFLRLTPGAEELVAALKAAGAKVVIISGGFTFLVEPIAER--LGIDYV 119
Query: 73 RLRELVAEQGGEVGLIVYCPHGPDDGCDCRKPKPGMLRQIGKHYGVDLSGIWFVGDSIGD 132
Sbjct: 120 VANELEIDDGKLTGRVVGPI------CD-GEGKAKALRELAAELGIPLEETVAYGDSAND 172
Query: 133 LEAARAVDCQPVLVKTGKGVRTLGK 157
Sbjct: 173 LPMLEAAG-LPIAVNPKPKLRALAD 196
>gnl|CDD|10517 COG0647, NagD, Predicted sugar phosphatases of the HAD superfamily
[Carbohydrate transport and metabolism]
Length = 269
Score = 36.0 bits (83), Expect = 0.006
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 103 KPKPGMLRQIGKHYGVDLSGIWFVGDSI-GDLEAARAVDCQPVLVKTGK-GVRTLGKPLP 160
Sbjct: 190 KPSPAIYEAALEKLGLDRSEVLMVGDRLDTDILGAKAAGLDTLLVLTGVSSAEDLDRAEV 249
Query: 161 EGTLIFDDLAAVASAL 176
Sbjct: 250 KPTYVVDSLAELITAL 265
Score = 31.7 bits (72), Expect = 0.10
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 18/71 (25%)
Query: 7 ILDRDGVINLDSDDYIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARGYYDLAV 66
Sbjct: 12 LFDLDGVLYRGNE----------AIPGAAEALKRLKAAGKPVIFLTNNSTRSR------- 54
Query: 67 LEAMHARLREL 77
Sbjct: 55 -EVVAARLSSL 64
>gnl|CDD|19063 KOG1274, KOG1274, WD40 repeat protein [General function prediction
only]
Length = 933
Score = 34.6 bits (79), Expect = 0.013
Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 3/51 (5%)
Query: 4 SLLILDRDGVINLDSDDYIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQ 54
Sbjct: 630 DPCIYDSEGTLLVLSRWRGNK---WIPILDTNKEIRKKSDHYWPVGLAYQQ 677
>gnl|CDD|10740 COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General
function prediction only]
Length = 229
Score = 32.6 bits (73), Expect = 0.050
Identities = 20/81 (24%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 97 DGCDCRKPKPGMLRQIGKHYGVDLSGIWFVGDSIG-DLEAARAVDCQPVLVKTGKGVRTL 155
Sbjct: 148 EDVGVAKPDPEIFEYALEKLGVPPEEALFVGDSLENDILGARALGMKTVWINRGGKPLPD 207
Query: 156 GKPLPEGTLIFDDLAAVASAL 176
Sbjct: 208 ALEAP--DYEISSLAELLDLL 226
>gnl|CDD|20668 KOG2882, KOG2882, p-Nitrophenyl phosphatase [Inorganic ion transport
and metabolism]
Length = 306
Score = 31.0 bits (70), Expect = 0.17
Identities = 12/48 (25%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 103 KPKPGMLRQIGKHYGVDLSGIWFVGDSIG-DLEAARAVDCQPVLVKTG 149
Sbjct: 224 KPSTFMFEYLLEKFNIDPSRTCMVGDRLDTDILFGKNCGFKTLLVLSG 271
Score = 29.5 bits (66), Expect = 0.51
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 10/56 (17%)
Query: 7 ILDRDGVINLDSDDYIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARGYY 62
Sbjct: 26 IFDCDGVLWLGE----------KPIPGSPEALNLLKSLGKQIIFVTNNSTKSREQY 71
>gnl|CDD|13479 COG4229, COG4229, Predicted enolase-phosphatase [Energy production
and conversion]
Length = 229
Score = 30.3 bits (68), Expect = 0.28
Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 111 QIGKHYGVDLSGIWFVGDSIGDLEAARAVDCQPVLVKTGKGVRTLGKPLP--EGTLIFDD 168
Sbjct: 168 KIAGDIGLPPAEILFLSDNPEELKAAAGVG-----LATGLAVRPGNAPVPDGQGFLVYKS 222
Query: 169 LA 170
Sbjct: 223 FE 224
>gnl|CDD|20894 KOG3109, KOG3109, Haloacid dehalogenase-like hydrolase [General
function prediction only]
Length = 244
Score = 29.9 bits (67), Expect = 0.41
Identities = 15/61 (24%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
Query: 88 IVYCPH-GPDDGCDCRKPKPGMLRQIGKHYGVDLSG-IWFVGDSIGDLEAARAVDCQPVL 145
Sbjct: 144 IICFETLNPIEKTVVCKPSEEAFEKAMKVAGIDSPRNTYFFDDSERNIQTAKEVGLKTVL 203
Query: 146 V 146
Sbjct: 204 V 204
>gnl|CDD|6485 pfam01526, Transposase_7, Transposase. This family includes
transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926
transposons from E-coli. The specific binding of the Tn3
transposase to DNA has been demonstrated. Sequence
analysis has suggested that the invariant triad of
Asp689, Asp765, Glu895 (numbering as in Tn3) may
correspond to the D-D-35-E motif previously implicated in
the catalysis of numerous transposases
Length = 968
Score = 28.3 bits (63), Expect = 1.0
Identities = 10/30 (33%), Positives = 12/30 (40%)
Query: 46 WTVAVATNQSGIARGYYDLAVLEAMHARLR 75
Sbjct: 442 WQRHVYDPDGGIDRRAYELCALFELRNALR 471
>gnl|CDD|10432 COG0561, Cof, Predicted hydrolases of the HAD superfamily [General
function prediction only]
Length = 264
Score = 27.8 bits (61), Expect = 1.8
Identities = 9/26 (34%), Positives = 15/26 (57%)
Query: 109 LRQIGKHYGVDLSGIWFVGDSIGDLE 134
Sbjct: 194 LQRLAKLLGIKLEEVIAFGDSTNDIE 219
>gnl|CDD|20062 KOG2276, KOG2276, Metalloexopeptidases [Amino acid transport and
metabolism]
Length = 473
Score = 27.2 bits (60), Expect = 2.4
Identities = 9/21 (42%), Positives = 14/21 (66%)
Query: 13 VINLDSDDYIKTLDEWIPIPS 33
Sbjct: 10 SIDLNKDEFINTLREAVAIQS 30
>gnl|CDD|20825 KOG3040, KOG3040, Predicted sugar phosphatase (HAD superfamily)
[General function prediction only]
Length = 262
Score = 26.8 bits (59), Expect = 2.7
Identities = 13/52 (25%), Positives = 22/52 (42%), Gaps = 8/52 (15%)
Query: 26 DEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARGYYDLAVLEAMHARLREL 77
Sbjct: 20 IEDAAVPGAVEALKRLRDQHVKVKFVTNTTKESK--------RNLHERLQRL 63
>gnl|CDD|10507 COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General
function prediction only]
Length = 221
Score = 27.0 bits (59), Expect = 3.0
Identities = 38/159 (23%), Positives = 56/159 (35%), Gaps = 19/159 (11%)
Query: 21 YIKTLDEWIPIPSSIEAIARLSQAGWTVAVATNQSGIARGYYDLAVLEAMHARLRELVAE 80
Sbjct: 78 EALELEGLKPIPGVVELLEQLKARGIPLAVASS--------SPRRAAERVLARLGLL--- 126
Query: 81 QGGEVGLIVYCPHGPDDGCDCRKPKPGMLRQIGKHYGVDLSGIWFVGDSIGDLEAARAVD 140
Sbjct: 127 --DYFDVIVTADDVAR-----GKPAPDIYLLAAERLGVDPEECVVVEDSPAGIQAAKAAG 179
Query: 141 CQPVLVKTGKGVRTLGKPLPEG-TLIFDDLAAVASALLQ 178
Sbjct: 180 MRVVGVPAGHDRPHLDPLDAHGADTVLLDLAELPALLEA 218
>gnl|CDD|20416 KOG2630, KOG2630, Enolase-phosphatase E-1 [Amino acid transport and
metabolism]
Length = 254
Score = 26.5 bits (58), Expect = 3.5
Identities = 17/61 (27%), Positives = 23/61 (37%), Gaps = 5/61 (8%)
Query: 102 RKPKPGMLRQIGKHYGVDLSGIWFVGDSIGDLEAARAVDCQPVLVKTGKGVRTLGKPLPE 161
Sbjct: 179 LKVESQSYKKIGHLIGKSPREILFLTDVPREAAAARKAGLQAGLV-----SRPGNAPLPD 233
Query: 162 G 162
Sbjct: 234 D 234
>gnl|CDD|12331 COG2987, HutU, Urocanate hydratase [Amino acid transport and
metabolism]
Length = 561
Score = 26.0 bits (57), Expect = 6.1
Identities = 11/39 (28%), Positives = 17/39 (43%), Gaps = 5/39 (12%)
Query: 114 KHYGVDLSGIWFVGDSIGDLEAARAVDCQPVLVKTGKGV 152
Sbjct: 159 QHFGGDLKGKWVLTAGLGGMGGA-----QPLAATMAGAV 192
>gnl|CDD|23845 pfam05621, TniB, Bacterial TniB protein. This family consists of
several bacterial TniB NTP-binding proteins. TniB is a
probable ATP-binding protein, which is involved in Tn5053
mercury resistance transposition
Length = 302
Score = 25.9 bits (56), Expect = 6.3
Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 4 SLLILDRDGVINLDSDDYIKTL--DEWIPIPSSIEAIARL 41
Sbjct: 10 SHLLPAAQGLARLPADERIQRIRADRWIGYPRAVEALNRL 49
>gnl|CDD|15656 pfam04358, DsrC, DsrC like protein. One family member has been
observed to co-purify with Desulfovibrio vulgaris
dissimilatory sulfite reductase, and many members of this
family are annotated as the third (gamma) subunit of
dissimilatory sulphite reductase. However, this protein
appears to be only loosely associated to the sulfite
reductase, which suggests that DsrC may not be an
integral part of the dissimilatory sulphite reductase.
Members of this family are found in organisms such as E.
coli and H. influenzae which do not contain dissimilatory
sulphite reductases but can synthesise assimilatory
sirohaem sulphite and nitrite reductases. It is
speculated that DsrC may be involved in the assembly,
folding or stabilisation of sirohaem proteins. The
strictly conserved cysteine in the C terminus suggests
that DsrC may have a catalytic function in the metabolism
of sulphur compounds
Length = 109
Score = 25.6 bits (56), Expect = 6.4
Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 7/40 (17%)
Query: 14 INLDSDDYIKTLDEWIPIPSSIEAIAR-----LSQAGWTV 48
Sbjct: 9 IELDEDGYLLDLDDW--DEEVAEALAKQEGIELTEEHWKI 46
>gnl|CDD|21332 KOG3549, KOG3549, Syntrophins (type gamma) [Extracellular structures]
Length = 505
Score = 25.8 bits (56), Expect = 7.2
Identities = 10/25 (40%), Positives = 16/25 (64%)
Query: 106 PGMLRQIGKHYGVDLSGIWFVGDSI 130
Sbjct: 81 PVVISKIYKDQAADITGQLFVGDAI 105
>gnl|CDD|18615 KOG0822, KOG0822, Protein kinase inhibitor [Cell cycle control, cell
division, chromosome partitioning]
Length = 649
Score = 25.3 bits (55), Expect = 7.8
Identities = 11/43 (25%), Positives = 15/43 (34%), Gaps = 3/43 (6%)
Query: 5 LLILDRDGVINLDSDD---YIKTLDEWIPIPSSIEAIARLSQA 44
Sbjct: 72 LQPICIPDVKLSGSDWNSKVVGKLSSWIELDSEDPKIRDLSEE 114
Lambda K H
0.320 0.141 0.426
Gapped
Lambda K H
0.267 0.0503 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 1100, Extension: 100
Number of Hits to DB: 2,999,465
Number of Sequences: 0
Number of extensions: 273427
Number of successful extensions: 131
Number of sequences better than 10.0: 1
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 128
length of query: 0
length of database: 5,506,404
effective HSP length: 87
effective length of query: -87
effective length of database: 3,937,011
effective search space: -342519957
effective search space used: 358268001
T: 11
A: 40
X1: 1600 (738.7 bits)
X2: 3800 (1463.8 bits)
X3: 6400 (2465.3 bits)
S1: 4100 (1895.7 bits)
S2: 61 (27.8 bits)