Score E
Sequences producing significant alignments: (bits) Value
gnl|CDD|10044 COG0169, AroE, Shikimate 5-dehydrogenase [Ami... 270 3e-73
gnl|CDD|16974 pfam01488, Shikimate_DH, Shikimate / quinate ... 258 1e-69
gnl|CDD|17595 pfam05200, GlutR_NAD_bind, Glutamyl-tRNAGlu r... 43 7e-05
gnl|CDD|20029 KOG2243, KOG2243, Ca2+ release channel (ryano... 27 4.6
gnl|CDD|10808 COG1086, COG1086, Predicted nucleoside-diphos... 27 4.6
gnl|CDD|16039 pfam04742, DUF611, Protein of unknown functio... 27 5.8
gnl|CDD|11142 COG1428, COG1428, Deoxynucleoside kinases [Nu... 26 9.4
>gnl|CDD|10044 COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and
metabolism]
Length = 283
Score = 270 bits (691), Expect = 3e-73
Identities = 119/277 (42%), Positives = 150/277 (54%), Gaps = 7/277 (2%)
Query: 1 MDRYCVFGNPIGHSKSPLIHRLFAEQTGEALVYDAQLAPLDDFPGFARRFFEQG-KGANV 59
Sbjct: 6 TKLFGVIGNPISHSLSPRMHNAAFRALGLDYVYLAFEVPPEDLPEAVSGIRALGFRGLNV 65
Query: 60 TVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLT-ANAGVELR 118
Sbjct: 66 TIPFKEAALPLLDELSPRARLIGAVNTLVREDDGKLRGYNTDGIGFLRALKEFGLPVDVT 125
Query: 119 GKRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLG-AVRGCGFAEV 177
Sbjct: 126 GKRVLILGAGGAARAVAFALAEAGAKRITVVNRTRERAEELADLFGELGAAVEAAALADL 185
Query: 178 EG--PFDLVVNGTSASLAGD-VPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAAR 234
Sbjct: 186 EGLEEADLLINATPVGMAGPEGDSPVPAELLPKGAIVYDVVYNPLETPLLREARAQG-AK 244
Query: 235 TLDGLGMLVEQAAEAFFLWRGVRPASAPVLETLRRQL 271
Sbjct: 245 TIDGLGMLVHQAAEAFELWTGVEPPVDVMKEALIEAL 281
>gnl|CDD|16974 pfam01488, Shikimate_DH, Shikimate / quinate 5-dehydrogenase. This
family contains both shikimate and quinate
dehydrogenases. Shikimate 5-dehydrogenase catalyses the
conversion of shikimate to 5-dehydroshikimate. This
reaction is part of the shikimate pathway which is
involved in the biosynthesis of aromatic amino acids.
Quinate 5-dehydrogenase catalyses the conversion of
quinate to 5-dehydroquinate. This reaction is part of the
quinate pathway where quinic acid is exploited as a
source of carbon in prokaryotes and microbial eukaryotes.
Both the shikimate and quinate pathways share two common
pathway metabolites 3-dehydroquinate and dehydroshikimate
Length = 240
Score = 258 bits (661), Expect = 1e-69
Identities = 119/241 (49%), Positives = 141/241 (58%), Gaps = 5/241 (2%)
Query: 20 HRLFAEQTGEALVYDAQLAPLDDFPGFARRFFEQG-KGANVTVPFKEEAYRLVDELSERA 78
Sbjct: 1 HNAAFEQLGLNHVYLAFETPPDDLRGAVEGFFALGFKGANVTIPFKEEAMPLLDELTPRA 60
Query: 79 TRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVELRGKRVLLLGAGGAVRGVLEPF 138
Sbjct: 61 KLIGAVNTLIREGDGKLRGDNTDGIGIRAALEEGLGFVRKGKTALILGAGGAARAVAYAL 120
Query: 139 LGECPAELLIANRTARKAVDLAERFADLGAVRGCGFAEVEG-PFDLVVNGTSASLAG--D 195
Sbjct: 121 LKLGVAKIYIANRTVEKAEALAERFGRYGAISVVSVSDLEGQAFDIIINATSVGLEPEID 180
Query: 196 VPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTLDGLGMLVEQAAEAFFLWRG 255
Sbjct: 181 DPPLSLSLLFKEGGVVYDMVYNPLTTPLLREAQARG-WKVIDGLGMLVEQGAEQFELWTG 239
Query: 256 V 256
Sbjct: 240 V 240
>gnl|CDD|17595 pfam05200, GlutR_NAD_bind, Glutamyl-tRNAGlu reductase, NAD(P) binding
domain. This family use NADPH as a cofactor. This family
is related to other NADPH binding domains
Length = 155
Score = 43.3 bits (102), Expect = 7e-05
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 116 ELRGKRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVRGCGFA 175
Sbjct: 19 SLSDKKVLVIGAGEMGELVAKHLLAKGVKKITIANRTLERAQALAEKL----GGEALPLN 74
Query: 176 EVE---GPFDLVVNGTSAS 191
Sbjct: 75 ELNEYLAEADVVISATSAP 93
>gnl|CDD|20029 KOG2243, KOG2243, Ca2+ release channel (ryanodine receptor) [Signal
transduction mechanisms]
Length = 5019
Score = 27.3 bits (60), Expect = 4.6
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 4 YCVFGNPIGHSKSPLIHRLFAEQTGEALVYDAQLAPLDDFP 44
Sbjct: 3596 YCLVEHPL-RSKKAVWHKLLSKQRKRAVVACFRMAPLYNLP 3635
>gnl|CDD|10808 COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases
[Cell envelope biogenesis, outer membrane / Carbohydrate
transport and metabolism]
Length = 588
Score = 27.2 bits (60), Expect = 4.6
Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 110 TANAGVELRGKRVLLLGAGGAV-RGVLEPFLGECPAELLIANRTARKAVDLAERFAD 165
Sbjct: 241 TELIGAMLTGKTVLVTGGGGSIGSELCRQILKFNPKEIILFSRDEYKLYLIDMELRE 297
>gnl|CDD|16039 pfam04742, DUF611, Protein of unknown function, DUF611. This family
includes several uncharacterised Bacillus halodurans
proteins
Length = 820
Score = 26.8 bits (59), Expect = 5.8
Identities = 9/28 (32%), Positives = 14/28 (50%)
Query: 47 ARRFFEQGKGANVTVPFKEEAYRLVDEL 74
Sbjct: 465 AREIFEQLQNGNSSIPFLKFILYLPKQE 492
>gnl|CDD|11142 COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and
metabolism]
Length = 216
Score = 26.0 bits (57), Expect = 9.4
Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 6/52 (11%)
Query: 2 DRYCVFGNPIGHSKSPLIHRLFAEQTGEALVYDAQLAPLDDFPGFARRFFEQ 53
Sbjct: 4 AMVIVIEGMIGAGKSTLAQAL-AEHLGFKVFYE----LVEDNP-FLDLFYED 49
Lambda K H
0.321 0.139 0.412
Gapped
Lambda K H
0.267 0.0501 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 1100, Extension: 100
Number of Hits to DB: 4,483,736
Number of Sequences: 0
Number of extensions: 420646
Number of successful extensions: 157
Number of sequences better than 10.0: 1
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 150
length of query: 0
length of database: 5,506,404
effective HSP length: 92
effective length of query: -92
effective length of database: 3,846,816
effective search space: -353907072
effective search space used: 700120512
T: 11
A: 40
X1: 1600 (741.9 bits)
X2: 3800 (1463.8 bits)
X3: 6400 (2465.3 bits)
S1: 4100 (1904.1 bits)
S2: 59 (27.0 bits)